Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Annaik Quemard"'
Autor:
Shiva Kumar Angala, Ana Carreras-Gonzalez, Emilie Huc-Claustre, Itxaso Anso, Devinder Kaur, Victoria Jones, Zuzana Palčeková, Juan M. Belardinelli, Célia de Sousa-d’Auria, Libin Shi, Nawel Slama, Christine Houssin, Annaïk Quémard, Michael McNeil, Marcelo E. Guerin, Mary Jackson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract We report on the existence of two phosphatidic acid biosynthetic pathways in mycobacteria, a classical one wherein the acylation of the sn-1 position of glycerol-3-phosphate (G3P) precedes that of sn-2 and another wherein acylations proceed
Externí odkaz:
https://doaj.org/article/e654bf1aa0a4424ea44490ddc8479d50
Autor:
Cécile Bon, Stéphanie Cabantous, Sylviane Julien, Valérie Guillet, Christian Chalut, Julie Rima, Yoann Brison, Wladimir Malaga, Angelique Sanchez-Dafun, Sabine Gavalda, Annaïk Quémard, Julien Marcoux, Geoffrey S. Waldo, Christophe Guilhot, Lionel Mourey
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Type I polyketide synthases (PKSs) are multifunctional enzymes responsible for the biosynthesis of a group of diverse natural compounds with biotechnological and pharmaceutical interest called polyketides. The diversity of polyket
Externí odkaz:
https://doaj.org/article/ce957ac87b34489ba429e3036d0705f9
Autor:
Bernardo Bazet Lyonnet, Lautaro Diacovich, Matías Cabruja, Fabienne Bardou, Annaïk Quémard, Gabriela Gago, Hugo Gramajo
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242528 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0099853.].
Externí odkaz:
https://doaj.org/article/dc649760b61b48348c1a0da53ea505cf
Autor:
Stevie Jamet, Nawel Slama, Joana Domingues, Françoise Laval, Pauline Texier, Nathalie Eynard, Annaik Quémard, Antonio Peixoto, Anne Lemassu, Mamadou Daffé, Kaymeuang Cam
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145883 (2015)
Gram positive mycobacteria with a high GC content, such as the etiological agent of tuberculosis Mycobacterium tuberculosis, possess an outer membrane mainly composed of mycolic acids (MAs), the so-called mycomembrane, which is essential for the cell
Externí odkaz:
https://doaj.org/article/a649a82760504c7e8d970333dd4ab4ef
Autor:
Bernardo Bazet Lyonnet, Lautaro Diacovich, Matías Cabruja, Fabienne Bardou, Annaïk Quémard, Gabriela Gago, Hugo Gramajo
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99853 (2014)
Mycobacteria contain a large variety of fatty acids which are used for the biosynthesis of several complex cell wall lipids that have been implicated in the ability of the organism to resist host defenses. The building blocks for the biosynthesis of
Externí odkaz:
https://doaj.org/article/fad22443856349268430e97b7cf34152
Publikováno v:
Science. 267:1638-1641
Resistance to isoniazid in Mycobacterium tuberculosis can be mediated by substitution of alanine for serine 94 in the InhA protein, the drug's primary target. InhA was shown to catalyze the beta-nicotinamide adenine dinucleotide (NADH)-specific reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7468199bf5a4efece64fe9308af9b86c
https://doi.org/10.1126/science.7886450
https://doi.org/10.1126/science.7886450
Autor:
Asesh Banerjee, G.W. de Lisle, V. Balasubramanian, Annaik Quemard, E. Dubnau, Kyung Sun Um, Desmond M. Collins, T. Wilson, William R. Jacobs
Publikováno v:
Science. 263:227-230
Isoniazid (isonicotinic acid hydrazide, INH) is one of the most widely used antituberculosis drugs, yet its precise target of action on Mycobacterium tuberculosis is unknown. A missense mutation within the mycobacterial inhA gene was shown to confer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96235b7c862ae049525d55ef2f370c8d
https://doi.org/10.1126/science.8284673
https://doi.org/10.1126/science.8284673
Autor:
William R. Jacobs, Jr.,‡,§, John S. Blanchard, Andréa Dessen, Annaik Quemard, Michelle Sugantino, and James C. Sacchettini
Publikováno v:
Journal of the American Chemical Society. 118:1561-1562
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c0fddb78be3e7bd7665aa70e7b1c371
https://doi.org/10.1021/ja950998b
https://doi.org/10.1021/ja950998b