Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population

Autor: Bing Yu, Claudia Flexeder, Robert W. McGarrah, Annah Wyss, Alanna C. Morrison, Kari E. North, Eric Boerwinkle, Gabi Kastenmüller, Christian Gieger, Karsten Suhre, Stefan Karrasch, Annette Peters, Gregory R. Wagner, Gregory A. Michelotti, Robert P. Mohney, Holger Schulz, Stephanie J. London

Publikováno v: Metabolites, Vol 9, Iss 4, p 61 (2019)

Determination of metabolomic signatures of pulmonary function and chronic obstructive pulmonary disease (COPD) in the general population could aid in identification and understanding of early disease processes. Metabolome measurements were performed

Externí odkaz: https://doaj.org/article/21171aff068a46f0914e383bec213e19

Data from Association of Marijuana Smoking with Oropharyngeal and Oral Tongue Cancers: Pooled Analysis from the INHANCE Consortium

Autor: Gypsyamber D'Souza, Mia Hashibe, Yuan-Chin Amy Lee, Paolo Boffetta, Marshall Posner, Leticia Fernandez, Alexander W. Daudt, Ana Menezes, Elena Matos, Sergio Koifman, Maria Paula Curado, Victor Wunsch-Filho, Thomas L. Vaughan, Chu Chen, Michael McClean, Philip Lazarus, Joshua Muscat, Hal Morgenstern, Zuo-Feng Zhang, Erich M. Sturgis, Qingyi Wei, Andrew F. Olshan, Paul Brennan, Annah Wyss, Elaine Smith, Stephen M. Schwartz, Julien Berthiller, Kurt Straif, Karl Kelsey, Anil K. Chaturvedi, Morgan A. Marks

Background: The incidence of oropharyngeal and oral tongue cancers has increased over the last 20 years which parallels increased use of marijuana among individuals born after 1950.Methods: A pooled analysis was conducted comprising individual-level

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01212a5aa0b4a65b1c4c9631de593804
https://doi.org/10.1158/1055-9965.c.6516394

Association of Marijuana Smoking with Oropharyngeal and Oral Tongue Cancers: Pooled Analysis from the INHANCE Consortium

Autor: Chu Chen, Maria Paula Curado, Zuo-Feng Zhang, Julien Berthiller, Alexander W. Daudt, Hal Morgenstern, Kurt Straif, Morgan A. Marks, Anil K. Chaturvedi, Michael D. McClean, Elaine M. Smith, Paul Brennan, Stephen M. Schwartz, Karl T. Kelsey, Gypsyamber D'Souza, Qingyi Wei, Erich M. Sturgis, Marshall Posner, Victor Wünsch-Filho, Mia Hashibe, Yuan Chin Amy Lee, Elena Matos, Andrew F. Olshan, Leticia Fernandez, Philip Lazarus, Paolo Boffetta, Thomas L. Vaughan, Ana M. B. Menezes, Annah Wyss, Joshua E. Muscat, Sergio Koifman

Publikováno v: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol 23, iss 1

Background: The incidence of oropharyngeal and oral tongue cancers has increased over the last 20 years which parallels increased use of marijuana among individuals born after 1950. Methods: A pooled analysis was conducted comprising individual-level

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1c965595703ce17d7b69362e22665c
https://doi.org/10.1158/1055-9965.epi-13-0181

Single nucleotide polymorphisms in nucleotide excision repair genes, cancer treatment, and head and neck cancer survival

Autor: Andrew F. Olshan, Annah Wyss, Mark C. Weissler, Jeannette T. Bensen, Christy L. Avery, Jill S. Barnholtz-Sloan, William K. Funkhouser, Amy H. Herring

Head and neck cancers (HNC) are commonly treated with radiation and platinum-based chemotherapy, which produce bulky DNA adducts to eradicate cancerous cells. Because nucleotide excision repair (NER) enzymes remove adducts, variants in NER genes may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8424554763fafb7bc3f69c7ff2c5d9

Single-Nucleotide Polymorphisms in Nucleotide Excision Repair Genes, Cigarette Smoking, and the Risk of Head and Neck Cancer

Autor: Annah Wyss, Mark C. Weissler, Amy H. Herring, Christy L. Avery, Jill S. Barnholtz-Sloan, William K. Funkhouser, Jeannette T. Bensen, Andrew F. Olshan

Background: Cigarette smoking is associated with increased head and neck cancer (HNC) risk. Tobacco-related carcinogens are known to cause bulky DNA adducts. Nucleotide excision repair (NER) genes encode enzymes that remove adducts and may be indepen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c48dca8c53892e1a09b777d2e71b36