Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Annabelle Hartt"'
Autor:
Andrew Poole, Vijaykumar Karuppiah, Annabelle Hartt, Jaafar N. Haidar, Sylvie Moureau, Tomasz Dobrzycki, Conor Hayes, Christopher Rowley, Jorge Dias, Stephen Harper, Keir Barnbrook, Miriam Hock, Charlotte Coles, Wei Yang, Milos Aleksic, Aimee Bence Lin, Ross Robinson, Joe D. Dukes, Nathaniel Liddy, Marc Van der Kamp, Gregory D. Plowman, Annelise Vuidepot, David K. Cole, Andrew D. Whale, Chandramouli Chillakuri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Cancers often harbor mutations in genes encoding important regulatory proteins, but therapeutic targeting of these molecules proves difficult due to their high structural similarity to their non-mutated counterpart. Here authors show the engineering
Externí odkaz:
https://doaj.org/article/d2f84672e7fe4eb3b7df368784cf9d36
Autor:
David Cole, Annelise Vuidepot, Andrew Whale, Andrew Poole, Vijaykumar Karuppiah, Annabelle Hartt, Jaafar Haidar, Sylvie Moureau, Aimee Bence Lin, Marc Van der Kamp, Gregory Plowman, Chandramouli Chillakuri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/f88c19af0c8e4b699fedf005b648101c
Autor:
Andrew, Poole, Vijaykumar, Karuppiah, Annabelle, Hartt, Jaafar N, Haidar, Sylvie, Moureau, Tomasz, Dobrzycki, Conor, Hayes, Christopher, Rowley, Jorge, Dias, Stephen, Harper, Keir, Barnbrook, Miriam, Hock, Charlotte, Coles, Wei, Yang, Milos, Aleksic, Aimee Bence, Lin, Ross, Robinson, Joe D, Dukes, Nathaniel, Liddy, Marc, Van der Kamp, Gregory D, Plowman, Annelise, Vuidepot, David K, Cole, Andrew D, Whale, Chandramouli, Chillakuri
Publikováno v:
Nature communications. 13(1)
Neoantigens derived from somatic mutations are specific to cancer cells and are ideal targets for cancer immunotherapy. KRAS is the most frequently mutated oncogene and drives the pathogenesis of several cancers. Here we show the identification and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09b6f49fe5f2b3f9dd982b4e6d4e47e8
https://pubmed.ncbi.nlm.nih.gov/36088370
https://pubmed.ncbi.nlm.nih.gov/36088370
Autor:
Annabelle Hartt, Andrew Whale, Jaafar N. Haidar, Gregory D. Plowman, Aimee Bence Lin, Andrew Poole, Marc W. van der Kamp, Annelise Vuidepot, Vijaykumar Karuppiah, David K. Cole, Sylvie Moureau, Chandramouli Chillakuri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundKRAS is the most frequently mutated oncogene, yet mutant KRAS has historically been a challenging target for conventional small molecule drug development. Tumour specific neoantigen peptides derived from KRAS are presented by cell surface h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ba4352c6c5f6c891c8975e1809ddab
https://doi.org/10.1136/jitc-2021-sitc2021.882
https://doi.org/10.1136/jitc-2021-sitc2021.882