Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Annabelle Friedrich"'
Autor:
Judith Neuwahl, Chantal A. Neumann, Annika C. Fitz, Anica D. Biermann, Maja Magel, Annabelle Friedrich, Lorenz Sellin, Björn Stork, Roland P. Piekorz, Peter Proksch, Wilfried Budach, Reiner U. Jänicke, Dennis Sohn
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-14 (2024)
Abstract The targeted elimination of radio- or chemotherapy-induced senescent cells by so-called senolytic substances represents a promising approach to reduce tumor relapse as well as therapeutic side effects such as fibrosis. We screened an in-hous
Externí odkaz:
https://doaj.org/article/e1d558cf63a94e08b3b6bbd7624c9ad0
Autor:
Lena Berning, Thomas Lenz, Ann Kathrin Bergmann, Gereon Poschmann, Hannah U. C. Brass, David Schlütermann, Annabelle Friedrich, María José Mendiburo, Céline David, Seda Akgün, Jörg Pietruszka, Kai Stühler, Björn Stork
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-24 (2023)
Abstract Background The bacterial secondary metabolite prodigiosin has been shown to exert anticancer, antimalarial, antibacterial and immunomodulatory properties. With regard to cancer, it has been reported to affect cancer cells but not non-maligna
Externí odkaz:
https://doaj.org/article/7ecfe60b57124e5b8a217be3a9ae7907
Autor:
Yadong Sun, Niklas Berleth, Wenxian Wu, David Schlütermann, Jana Deitersen, Fabian Stuhldreier, Lena Berning, Annabelle Friedrich, Seda Akgün, María José Mendiburo, Sebastian Wesselborg, Marcus Conrad, Carsten Berndt, Björn Stork
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-14 (2021)
Abstract Ferroptosis is a form of regulated cell death that emerges to be relevant for therapy-resistant and dedifferentiating cancers. Although several lines of evidence suggest that ferroptosis is a type of autophagy-dependent cell death, the under
Externí odkaz:
https://doaj.org/article/7bca77462e6c49c99c7636951cca1cac
Autor:
David Schlütermann, Niklas Berleth, Jana Deitersen, Nora Wallot-Hieke, Olena Friesen, Wenxian Wu, Fabian Stuhldreier, Yadong Sun, Lena Berning, Annabelle Friedrich, María José Mendiburo, Christoph Peter, Constanze Wiek, Helmut Hanenberg, Anja Stefanski, Kai Stühler, Björn Stork
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The protein kinase TBK1 is a central regulator of innate immune responses and autophagy, and ablation of either function has been linked to neuroinflammatory or degenerative diseases. Autophagy is an intracellular process that recycles old o
Externí odkaz:
https://doaj.org/article/6972ad6fb1594ad394a0391385e1a71d
Autor:
Jana Deitersen, Lena Berning, Fabian Stuhldreier, Sara Ceccacci, David Schlütermann, Annabelle Friedrich, Wenxian Wu, Yadong Sun, Philip Böhler, Niklas Berleth, María José Mendiburo, Sabine Seggewiß, Ruchika Anand, Andreas S. Reichert, Maria Chiara Monti, Peter Proksch, Björn Stork
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-18 (2021)
Abstract Autophagy is an intracellular recycling pathway with implications for intracellular homeostasis and cell survival. Its pharmacological modulation can aid chemotherapy by sensitizing cancer cells toward approved drugs and overcoming chemoresi
Externí odkaz:
https://doaj.org/article/b65cf7fd707d4b28b29b94e366981677
Autor:
Lena Berning, David Schlütermann, Annabelle Friedrich, Niklas Berleth, Yadong Sun, Wenxian Wu, María José Mendiburo, Jana Deitersen, Hannah U. C. Brass, Margaretha A. Skowron, Michèle J. Hoffmann, Günter Niegisch, Jörg Pietruszka, Björn Stork
Publikováno v:
Molecules, Vol 26, Iss 5, p 1294 (2021)
Cisplatin-based treatment is the standard of care therapy for urothelial carcinomas. However, complex cisplatin resistance mechanisms limit the success of this approach. Both apoptosis and autophagy have been shown to contribute to this resistance. P
Externí odkaz:
https://doaj.org/article/14a3d2f23be8408f9da609e017ad8f1a
Autor:
Anh Nguyen, Francesca Lugarini, Céline David, Pouya Hosnani, Çağla Alagöz, Annabelle Friedrich, David Schlütermann, Barbora Knotkova, Anoshi Patel, Iwan Parfentev, Henning Urlaub, Michael Meinecke, Björn Stork, Alex C. Faesen
Publikováno v:
Molecular Cell
Autophagy is a conserved intracellular degradation pathway that generates de novo double-membrane autophagosomes to target a wide range of material for lysosomal degradation. In multicellular organisms, autophagy initiation requires the timely assemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8a8058f25c3ca17781ff6f2e84c762
https://hdl.handle.net/21.11116/0000-000D-592A-121.11116/0000-000D-592C-F
https://hdl.handle.net/21.11116/0000-000D-592A-121.11116/0000-000D-592C-F
Autor:
Anh Nguyen, Francesca Lugarini, Céline David, Pouya Hosnani, Barbora Knotkova, Anoshi Patel, Iwan Parfentev, Annabelle Friedrich, Henning Urlaub, Michael Meinecke, Björn Stork, Alex C. Faesen
Autophagy is a conserved intracellular degradation pathway that uses de novo doublemembrane vesicle (autophagosome) formation to target a wide range of cytoplasmic material for lysosomal degradation. In multicellular organisms, autophagy initiation r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b01abd7a6af9f1446a4e68ff1ed9bea4
https://doi.org/10.1101/2022.09.21.508836
https://doi.org/10.1101/2022.09.21.508836
Autor:
Jörg Pietruszka, Margaretha A. Skowron, Günter Niegisch, Yadong Sun, Lena Berning, Jana Deitersen, Niklas Berleth, Annabelle Friedrich, Wenxian Wu, Michèle J. Hoffmann, Björn Stork, Hannah U. C. Brass, David Schlütermann, María José Mendiburo
Publikováno v:
Molecules
Molecules 26(5), 1294-(2021). doi:10.3390/molecules26051294
Volume 26
Issue 5
Molecules, Vol 26, Iss 1294, p 1294 (2021)
Molecules 26(5), 1294-(2021). doi:10.3390/molecules26051294
Volume 26
Issue 5
Molecules, Vol 26, Iss 1294, p 1294 (2021)
Cisplatin-based treatment is the standard of care therapy for urothelial carcinomas. However, complex cisplatin resistance mechanisms limit the success of this approach. Both apoptosis and autophagy have been shown to contribute to this resistance. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06d5eda58a37d38fe2c1d52cad65d80
https://pubmed.ncbi.nlm.nih.gov/33673611
https://pubmed.ncbi.nlm.nih.gov/33673611
Autor:
Thomas Kurz, Finn K. Hansen, Matthias U. Kassack, Lena Schumacher, Gerhard Fritz, Annabelle Friedrich, Marc Pflieger, Wynand P. Roos, Jana van Stuijvenberg, Ann-Sophie Assmann, Wolfgang A. Schulz
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 13
International Journal of Molecular Sciences, Vol 21, Iss 4747, p 4747 (2020)
Volume 21
Issue 13
International Journal of Molecular Sciences, Vol 21, Iss 4747, p 4747 (2020)
Histone deacetylase inhibitors (HDACi) are already approved for the therapy of leukemias. Since they are also emerging candidate compounds for the treatment of non-malignant diseases, HDACi with a wide therapeutic window and low hazard potential are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2c84ff331382059cb4dc4559e390ec