Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Annabelle B. Blum"'
Autor:
Haiyin Liu, Kayla R. Wilson, Ashley M. Firth, Christophe Macri, Patrick Schriek, Annabelle B. Blum, Javiera Villar, Samuel Wormald, Mitch Shambrook, Bangyan Xu, Hui Jing Lim, Hamish E. G. McWilliam, Andrew F. Hill, Laura E. Edgington-Mitchell, Irina Caminschi, Mireille H. Lahoud, Elodie Segura, Marco J. Herold, Jose A. Villadangos, Justine D. Mintern
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Regulated trafficking of major histocompatibility complex class II and CD86 is a prerequisite of antigen presenting cell functionality. Authors show here that ubiquitin-like protein 3 is critically involved in the ubiquitination process that controls
Externí odkaz:
https://doaj.org/article/e0c1150585254283885c639c972afad3
Autor:
F Victor Makota, Haiyin Liu, Jose A Villadangos, Kayla R. Wilson, Satoshi Ishido, Mireille H. Lahoud, Annabelle B. Blum, Christophe Macri, Scott N. Mueller, Justine D. Mintern, Devi Jenika, Patrick Schriek, Bangyan Xu, Irina Caminschi, Dominik Schienstock, Laura E Edgington-Mitchell, Lauren Francis
Publikováno v:
The Journal of Immunology. 207:2255-2264
MHC class II (MHC II) Ag presentation by dendritic cells (DCs) is critical for CD4+ T cell immunity. Cell surface levels of MHC II loaded with peptide is controlled by ubiquitination. In this study, we have examined how MHC II ubiquitination impacts
Autor:
Lauren Francis, Annabelle B. Blum, Kayla R. Wilson, Champa Nataraja, Daniel H.D. Gray, Melanie Heinlein, Haiyin Liu, Justine D. Mintern, Jose A Villadangos, Christophe Macri, Patrick Schriek, James Harris, Sarah Jones
Publikováno v:
The Journal of Immunology. 205:1207-1216
MHC class II (MHC II) displays peptides at the cell surface, a process critical for CD4+ T cell development and priming. Ubiquitination is a mechanism that dictates surface MHC II with the attachment of a polyubiquitin chain to peptide-loaded MHC II,