Výsledky vyhledávání - "Annabelle, Hurtier"

Genetically-encoded BRET probes shed light on ligand bias–induced variable ion selectivity in TRPV1 and P2X5/7

Autor: Yann Loïck Chappe, Sandra Pierredon, Alexandre Joushomme, Pablo Molle, André Garenne, Anne Canovi, Solène Barbeau, Florence Poulletier De Gannes, Annabelle Hurtier, Isabelle Lagroye, Thomas Ducret, Jean-François Quignard, Vincent Compan, Yann Percherancier

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (46), pp.e2205207119. ⟨10.1073/pnas.2205207119⟩

Whether ion channels experience ligand-dependent dynamic ion selectivity remains of critical importance since this could support ion channel functional bias. Tracking selective ion permeability through ion channels, however, remains challenging even

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8c94dfcd1beb84469e47a4650ab064
https://hal.science/hal-03847529/file/pnas.2205207119.pdf

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Genetically-encoded BRET probes enlight ligand bias-induced variable ion selectivity in TRPV1 and P2X5/7

Autor: Yann Chappe, Sandra Pierredon, Alexandre Joushomme, Pablo Molle, André Garenne, Anne Canovi, Solène Barbeau, Florence Poulletier De Gannes, Annabelle Hurtier, Isabelle Lagroye, Thomas Ducret, Jean-François Quignard, Vincent Compan, Yann Percherancier

Publikováno v: Biophysical Journal. 122:320a-321a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae6bb18ed81d261a4f5cf8e3aa64b662
https://doi.org/10.1016/j.bpj.2022.11.1796

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Label-Free Study of the Global Cell Behavior during Exposure to Environmental Radiofrequency Fields in the Presence or Absence of Pro-Apoptotic or Pro-Autophagic Treatments

Autor: Alexandre Joushomme, André Garenne, Mélody Dufossée, Rémy Renom, Hermanus Johannes Ruigrok, Yann Loick Chappe, Anne Canovi, Lorenza Patrignoni, Annabelle Hurtier, Florence Poulletier de Gannes, Isabelle Lagroye, Philippe Lévêque, Noëlle Lewis, Muriel Priault, Delia Arnaud-Cormos, Yann Percherancier

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 658, p 658 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Medicine and Advanced Sciences
International Journal of Molecular Medicine and Advanced Sciences, 2022, 23 (2), pp.658. ⟨10.3390/ijms23020658⟩
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 658

International audience; It remains controversial whether exposure to environmental radiofrequency signals (RF) impacts cell status or response to cellular stress such as apoptosis or autophagy. We used two label-free techniques, cellular impedancemet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2a2c9236023824e2e1e7ec1988ac67
https://www.mdpi.com/1422-0067/23/2/658

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High-Throughput Screening of TRPV1 Ligands in the Light of the Bioluminescence Resonance Energy Transfer Technique

Autor: Christelle Franchet, Pauline Michel, Vincent Compan, Thomas Ducret, Solène Barbeau, Alexandre Joushomme, Florence Poulletier de Gannes, Stanislas Mayer, Sandra Pierredon, André Garenne, Yann Chappe, Annabelle Hurtier, Jean-François Quignard, Isabelle Lagroye, Y. Percherancier, Luc Baron

Publikováno v: Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2021, 100 (3), pp.237-257. ⟨10.1124/molpharm.121.000271⟩

International audience; Ion channels are attractive drug targets for many therapeutic applications. However, high-throughput screening (HTS) of drug candidates is difficult and remains very expensive. We thus assessed the suitability of the biolumine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c29b88c9bf57b40568b5053b212a2c1
https://hal.archives-ouvertes.fr/hal-03428370

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High-Throughput Screening of Transient Receptor Potential Channel 1 Ligands in the Light of the Bioluminescence Resonance Energy Transfer Technique

Autor: Yann, Chappe, Pauline, Michel, Alexandre, Joushomme, Solène, Barbeau, Sandra, Pierredon, Luc, Baron, André, Garenne, Florence, Poulletier De Gannes, Annabelle, Hurtier, Stanislas, Mayer, Isabelle, Lagroye, Jean-François, Quignard, Thomas, Ducret, Vincent, Compan, Christelle, Franchet, Yann, Percherancier

Publikováno v: Molecular pharmacology. 100(3)

Ion channels are attractive drug targets for many therapeutic applications. However, high-throughput screening (HTS) of drug candidates is difficult and remains very expensive. We thus assessed the suitability of the bioluminescence resonance energy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6b8c3c6ba4ae494f7942727c643bc815
https://pubmed.ncbi.nlm.nih.gov/34548322

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Effects of radiofrequency field exposure on proteotoxic-induced and heat-induced HSF1 response in live cells using the bioluminescence resonance energy transfer technique

Autor: Isabelle Lagroye, Denis Habauzit, Delia Arnaud-Cormos, Annabelle Hurtier, Yann Chappe, Yves Le Dréan, Catherine Martin, Hermanus J. Ruigrok, André Garenne, Emmanuelle Poque, Yann Percherancier, Philippe Lévêque, Florence Poulletier de Gannes

Publikováno v: Cell Stress and Chaperones
Cell Stress and Chaperones, 2021, 26 (1), pp.241-251. ⟨10.1007/s12192-020-01172-3⟩
Cell Stress and Chaperones, Springer Verlag, 2021, 26 (1), pp.241-251. ⟨10.1007/s12192-020-01172-3⟩
Cell Stress Chaperones

As of today, only acute effects of RF fields have been confirmed to represent a potential health hazard and they are attributed to non-specific heating (≥ 1 °C) under high-level exposure. Yet, the possibility that environmental RF impact living ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3280633da1e67cc2607504178ef87c5
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02996055/document

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