Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Annabelle, Chow"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Triple negative breast cancer (TNBC) is an aggressive malignancy with poor prognosis, in part because of the current lack of any approved molecularly targeted therapy. We evaluated various combinations of three different drugs: ni
Externí odkaz:
https://doaj.org/article/03b6d244b7c24be2ba561f6b2a274258
Autor:
Robert S. Kerbel, Paul M. Krzyzanowski, Jessica K. Miller, Yogi Sundaravadanam, Shan Man, Ping Xu, Annabelle Chow, Janna Krueger, Elizabeth A. Kuczynski
A recurring historic finding in cancer drug development is encouraging antitumor effects observed in tumor-bearing mice that fail to translate into the clinic. An intriguing exception to this pattern is immune checkpoint therapy, as the sustained tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baee568ced6be1d2f9250d3b9c574f4a
https://doi.org/10.1158/1535-7163.c.6539352.v1
https://doi.org/10.1158/1535-7163.c.6539352.v1
Autor:
Robert S. Kerbel, Paul M. Krzyzanowski, Jessica K. Miller, Yogi Sundaravadanam, Shan Man, Ping Xu, Annabelle Chow, Janna Krueger, Elizabeth A. Kuczynski
Supplementary Table S1 lists missense mutations in mutagenized EMT-6/P variant cells. Supplementary Table S2 lists driver mutations in mutagenized EMT-6/P variant cells. Supplementary Table S3 lists the results of functional annotation clustering of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162a56b986da2267586f55fbb33b65ef
https://doi.org/10.1158/1535-7163.22509624
https://doi.org/10.1158/1535-7163.22509624
Autor:
Robert S. Kerbel, Paul M. Krzyzanowski, Jessica K. Miller, Yogi Sundaravadanam, Shan Man, Ping Xu, Annabelle Chow, Janna Krueger, Elizabeth A. Kuczynski
Supplementary Figure S1 shows the gating strategy used to identify tumor-infiltrating immune cells. Supplementary Figure S2 shows in vitro survival and viability of tumor cell variants following mutagen treatment and after their recovery, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6619a1cdd2f93be720ea2c81bfe7c126
https://doi.org/10.1158/1535-7163.22509627
https://doi.org/10.1158/1535-7163.22509627
Autor:
Robert S. Kerbel, Paul M. Krzyzanowski, Jessica K. Miller, Yogi Sundaravadanam, Shan Man, Ping Xu, Annabelle Chow, Janna Krueger, Elizabeth A. Kuczynski
Supplementary materials and methods and legends for Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473965427a9af0fff6e75ae8f6959256
https://doi.org/10.1158/1535-7163.22509621.v1
https://doi.org/10.1158/1535-7163.22509621.v1
Autor:
Robert S. Kerbel, F. Stuart Foster, Scott Eliasof, Douglas Lazarus, Annabelle Chow, Ellen Rohde, Lata Jayaraman, Shan Man, Ping Xu, Donna Brown, Christina R. Lee, Christian G. Peters, Melissa Yin, Elizabeth Pham
VEGF pathway–targeting antiangiogenic drugs, such as bevacizumab, when combined with chemotherapy have changed clinical practice for the treatment of a broad spectrum of human cancers. However, adaptive resistance often develops, and one major mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8326e19cc9586d17287f85a14d80afba
https://doi.org/10.1158/0008-5472.c.6508295.v1
https://doi.org/10.1158/0008-5472.c.6508295.v1
Autor:
Robert S. Kerbel, Urban Emmenegger, Steven R. Pirie-Shepherd, Christina R. Lee, Marta Paez-Ribes, Annabelle Chow, Ping Xu, Shan Man, Florence T.H. Wu
Supplemental Figure S1. Primary LM2-4luc16 breast tumors treated with CVX-2000, vehicle only, sunitinib, CVX-060, or sunitinib plus CVX-060. Supplemental Figure S2. Direct inhibitory effects of sunitinib and regorafenib on endothelial Tie2 vs. VEGFR2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50965c341b66780611b413169ae8ef80
https://doi.org/10.1158/0008-5472.22413203
https://doi.org/10.1158/0008-5472.22413203
Autor:
Robert S. Kerbel, F. Stuart Foster, Scott Eliasof, Douglas Lazarus, Annabelle Chow, Ellen Rohde, Lata Jayaraman, Shan Man, Ping Xu, Donna Brown, Christina R. Lee, Christian G. Peters, Melissa Yin, Elizabeth Pham
Description of additional methods and procedures used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c81d37323519ca66c2f3c1b5eb841b0
https://doi.org/10.1158/0008-5472.22411781
https://doi.org/10.1158/0008-5472.22411781
Autor:
Robert S. Kerbel, Urban Emmenegger, Steven R. Pirie-Shepherd, Christina R. Lee, Marta Paez-Ribes, Annabelle Chow, Ping Xu, Shan Man, Florence T.H. Wu
Supplemental Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d421541d9d62570585bc502b242b19
https://doi.org/10.1158/0008-5472.22413200.v1
https://doi.org/10.1158/0008-5472.22413200.v1
Autor:
Robert S. Kerbel, F. Stuart Foster, Scott Eliasof, Douglas Lazarus, Annabelle Chow, Ellen Rohde, Lata Jayaraman, Shan Man, Ping Xu, Donna Brown, Christina R. Lee, Christian G. Peters, Melissa Yin, Elizabeth Pham
Bioluminescence imaging of mice bearing primary LM2-4 tumors (S1); Assessment of MVD, HIF-1α, and tumoral drug accumulation in PDX primary tumors (S2); Immunohistochemistry staining for CD31, CAIX, caspase 3, Ki67, and HIF-1α, as well as in vitro V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173d464fc496bfd3274a5bef741dced1
https://doi.org/10.1158/0008-5472.22411784
https://doi.org/10.1158/0008-5472.22411784