Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Annabell, Bachem"'
Autor:
Ariane Renita Lee, Kayla Roberta Wilson, Michele Clarke, Sven Engel, David C. Tscharke, Thomas Gebhardt, Sammy Bedoui, Annabell Bachem
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Naïve CD8+ T cells need to undergo a complex and coordinated differentiation program to gain the capacity to control virus infections. This not only involves the acquisition of effector functions, but also regulates the development of a subset of ef
Externí odkaz:
https://doaj.org/article/2877a29d80cc47ed971eff0a6165bbc2
Autor:
Georgia Deliyannis, Chinn Yi Wong, Hayley A. McQuilten, Annabell Bachem, Michele Clarke, Xiaoxiao Jia, Kylie Horrocks, Weiguang Zeng, Jason Girkin, Nichollas E. Scott, Sarah L. Londrigan, Patrick C. Reading, Nathan W. Bartlett, Katherine Kedzierska, Lorena E. Brown, Francesca Mercuri, Christophe Demaison, David C. Jackson, Brendon Y. Chua
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
The impact of respiratory virus infections on global health is felt not just during a pandemic, but endemic seasonal infections pose an equal and ongoing risk of severe disease. Moreover, vaccines and antiviral drugs are not always effective or avail
Externí odkaz:
https://doaj.org/article/4dfcfe2f932a406887c4b13f84a6c4e2
Autor:
M Isabel G Lopez Sanchez, Mark Ziemann, Annabell Bachem, Rahul Makam, Jonathan G Crowston, Carl A Pinkert, Matthew McKenzie, Sammy Bedoui, Ian A Trounce
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239804 (2020)
Mitochondrial OXPHOS generates most of the energy required for cellular function. OXPHOS biogenesis requires the coordinated expression of the nuclear and mitochondrial genomes. This represents a unique challenge that highlights the importance of nuc
Externí odkaz:
https://doaj.org/article/2cced9624dea4914a6324b4c271febea
Autor:
Sven Engel, Annabell Bachem, Richard A Strugnell, Andreas Strasser, Marco J Herold, Sammy Bedoui
Publikováno v:
Current Opinion in Immunology. 83:102343
Autor:
Marie Greyer, Paul G. Whitney, Angus T. Stock, Gayle M. Davey, Christina Tebartz, Annabell Bachem, Justine D. Mintern, Richard A. Strugnell, Stephen J. Turner, Thomas Gebhardt, Meredith O’Keeffe, William R. Heath, Sammy Bedoui
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 586-597 (2016)
DCs often require stimulation from CD4+ T cells to propagate CD8+ T cell responses, but precisely how T cell help optimizes the priming capacity of DCs and why this appears to differ between varying types of CD8+ T cell immunity remains unclear. We s
Externí odkaz:
https://doaj.org/article/be08f708f5dd41d3bc8b76a55427c369
Autor:
Elise Gressier, Jonas Schulte-Schrepping, Lev Petrov, Sophia Brumhard, Paula Stubbemann, Anna Hiller, Benedikt Obermayer, Jasper Spitzer, Tomislav Kostevc, Paul G. Whitney, Annabell Bachem, Alexandru Odainic, Carolien van de Sandt, Thi H. O. Nguyen, Thomas Ashhurst, Kayla Wilson, Clare V. L. Oates, Linden. J. Gearing, Tina Meischel, Katharina Hochheiser, Marie Greyer, Michele Clarke, Maike Kreutzenbeck, Sarah S. Gabriel, Wolfgang Kastenmüller, Christian Kurts, Sarah L. Londrigan, Axel Kallies, Katherine Kedzierska, Paul J. Hertzog, Eicke Latz, Yu-Chen E. Chen, Kristen J. Radford, Michael Chopin, Jan Schroeder, Florian Kurth, Thomas Gebhardt, Leif E. Sander, Birgit Sawitzki, Joachim L. Schultze, Susanne V. Schmidt, Sammy Bedoui
Publikováno v:
Nature immunology 24(6), 979-990 (2023). doi:10.1038/s41590-023-01517-x
Antiviral CD8+ T cell immunity depends on the integration of various contextual cues, but how antigen-presenting cells (APCs) consolidate these signals for decoding by T cells remains unclear. Here, we describe gradual interferon-α/interferon-β (IF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fa2efef3db05d38b32977cd1c0284b
Autor:
Andrew S Brown, Chao Yang, Ka Yee Fung, Annabell Bachem, Dorothée Bourges, Sammy Bedoui, Elizabeth L Hartland, Ian R van Driel
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005691 (2016)
Legionella pneumophila is the causative agent of Legionnaires' disease, a potentially fatal lung infection. Alveolar macrophages support intracellular replication of L. pneumophila, however the contributions of other immune cell types to bacterial ki
Externí odkaz:
https://doaj.org/article/462e61b3197d46818e1ddcf884236d0b
Autor:
Andreas Strasser, Sammy Bedoui, Annabell Bachem, Sven Engel, Marcel Doerflinger, Marco J Herold, Ariane R Lee
Publikováno v:
Cell Death Differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d710c035e7c529bf773e5ebae3d7fb
https://europepmc.org/articles/PMC8629988/
https://europepmc.org/articles/PMC8629988/
Autor:
Gayle M. Davey, Asolina Braun, Ian A. Parish, Simone Nüssing, Simone L Park, Elise Gressier, David Freestone, Emma Grace Bawden, Teagan Wagner, Tony Tiganis, Annabell Bachem, David E. Gyorki, Moshe Olshansky, Brendan E. Russ, Robyn McConville, Claerwen M. Jones, Sammy Bedoui, David C. Tscharke, Stephen J. Turner, Katharina Hochheiser, Thomas Gebhardt, Marco J Herold, Florian Wiede, Matthias H. Enders
Publikováno v:
The Journal of Experimental Medicine
Hochheiser et al. identify Ptpn2 and KLRG1 as new regulators of CD103+ CD8+ TRM cells in mouse skin. While KLRG1 inhibits TRM formation, genetic Ptpn2 deficiency increases the protective function of TRM cells in infection but aggravates TRM-dependent
Autor:
David C. Jackson, Weiguang Zeng, Xiaoxiao Jia, Jason Girkin, Kylie J. Horrocks, Chinn Yi Wong, Patrick C. Reading, Nathan W. Bartlett, Michele V Clarke, Hayley A McQuilten, Georgia Deliyannis, Christophe Demaison, Sarah L. Londrigan, Lorena E. Brown, Francesca A. Mercuri, Katherine Kedzierska, Nichollas E. Scott, Brendon Y. Chua, Annabell Bachem
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
JCI Insight
JCI Insight
The impact of respiratory virus infections on global health is felt not just during a pandemic, but endemic seasonal infections pose an equal and ongoing risk of severe disease. Moreover, vaccines and antiviral drugs are not always effective or avail