Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Annabel Krappitz"'
Autor:
Regina Nacken, Nigel W. Bunnett, Jane E. Murphy, Silke Haerteis, Hyunjae Chung, Christoph Korbmacher, Matteus Krappitz, Morley D. Hollenberg, Annabel Krappitz, Wolfgang Knecht, Marko Bertog, Bettina Krueger
Publikováno v:
The Journal of biological chemistry. 289(27)
Proteolytic activation is a unique feature of the epithelial sodium channel (ENaC). However, the underlying molecular mechanisms and the physiologically relevant proteases remain to be identified. The serine protease trypsin I can activate ENaC in vi
Autor:
Wolfgang Knecht, Annabel Krappitz, Jane E. Murphy, Silke Haerteis, Christoph Korbmacher, Matteus Krappitz, Nigel W. Bunnett
Publikováno v:
The FASEB Journal. 28
Proteolytic channel activation is a unique feature of the epithelial sodium channel (ENaC) but is not yet fully understood. The serine protease trypsin is known to activate ENaC in vitro but may no...
Autor:
Alexei Diakov, Silke Haerteis, Christoph Korbmacher, Matteus Krappitz, Annabel Krappitz, Robert Rauh
Publikováno v:
The Journal of General Physiology
Proteolytic activation of the epithelial sodium channel (ENaC) involves cleavage of its γ subunit in a critical region targeted by several proteases. Our aim was to identify cleavage sites in this region that are functionally important for activatio
Autor:
Nigel W. Bunnett, Erik Lindström, Silke Haerteis, Annabel Krappitz, Christoph Korbmacher, Matteus Krappitz, Jane E. Murphy, Ian Henderson, Marko Bertog, Vera Baraznenok
Publikováno v:
Pflugers Archiv
Proteolytic processing of the amiloride-sensitive epithelial sodium channel (ENaC) by serine proteases is known to be important for channel activation. Inappropriate ENaC activation by proteases may contribute to the pathophysiology of cystic fibrosi