Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Anna-Lisa Doebley"'
Autor:
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Nucleosome profiling from cell-free DNA (cfDNA) represents a potential approach for cancer detection and classification. Here, the authors develop Griffin, a computational framework for tumour subtype classification based on cfDNA nucleosome profilin
Externí odkaz:
https://doaj.org/article/a2aa19ff06af40648abe298b2dc9bb6b
Autor:
Samuel Terkper Ahuno, Anna-Lisa Doebley, Thomas U. Ahearn, Joel Yarney, Nicholas Titiloye, Nancy Hamel, Ernest Adjei, Joe-Nat Clegg-Lamptey, Lawrence Edusei, Baffour Awuah, Xiaoyu Song, Verna Vanderpuye, Mustapha Abubakar, Maire Duggan, Daniel G. Stover, Kofi Nyarko, John M. S. Bartlett, Francis Aitpillah, Daniel Ansong, Kevin L. Gardner, Felix Andy Boateng, Anne M. Bowcock, Carlos Caldas, William D. Foulkes, Seth Wiafe, Beatrice Wiafe-Addai, Montserrat Garcia-Closas, Alexander Kwarteng, Gavin Ha, Jonine D. Figueroa, Paz Polak, the Ghana Breast Health Study Team
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Abstract Circulating tumor DNA (ctDNA) sequencing studies could provide novel insights into the molecular pathology of cancer in sub-Saharan Africa. In 15 patient plasma samples collected at the time of diagnosis as part of the Ghana Breast Health St
Externí odkaz:
https://doaj.org/article/0fd72a4af12c4bc4bb78096b172d0185
Autor:
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/0c649e0ae1ad4fdc955cfa5df22bd466
Autor:
Katherine Kretovich Billmyre, Anna-Lisa Doebley, Maya Spichal, Bree Heestand, Tony Belicard, Aya Sato-Carlton, Stephane Flibotte, Matt Simon, Megan Gnazzo, Ahna Skop, Donald Moerman, Peter Mark Carlton, Peter Sarkies, Shawn Ahmed
Publikováno v:
PLoS Genetics, Vol 15, Iss 3, p e1008004 (2019)
Germ cell immortality, or transgenerational maintenance of the germ line, could be promoted by mechanisms that could occur in either mitotic or meiotic germ cells. Here we report for the first time that the GSP-2 PP1/Glc7 phosphatase promotes germ ce
Externí odkaz:
https://doaj.org/article/46b4042dfcd148619e663021990ba73b
Autor:
Sarah Aileen Lewis, Tetsuya Takimoto, Shima Mehrvar, Hitoshi Higuchi, Anna-Lisa Doebley, Giangela Stokes, Nader Sheibani, Sakae Ikeda, Mahsa Ranji, Akihiro Ikeda
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201986 (2018)
Tissues with high-energy demand including the heart are rich in the energy-producing organelles, mitochondria, and sensitive to mitochondrial dysfunction. While alterations in mitochondrial function are increasingly recognized in cardiovascular disea
Externí odkaz:
https://doaj.org/article/ff1953c15c2c46ea8bd53a439651a14a
Autor:
Matt Simon, Peter Sarkies, Kohta Ikegami, Anna-Lisa Doebley, Leonard D. Goldstein, Jacinth Mitchell, Aisa Sakaguchi, Eric A. Miska, Shawn Ahmed
Publikováno v:
Cell Reports, Vol 7, Iss 3, Pp 762-773 (2014)
Defects in the Piwi/piRNA pathway lead to transposon desilencing and immediate sterility in many organisms. We found that the C. elegans Piwi mutant prg-1 became sterile after growth for many generations. This phenotype did not occur for RNAi mutants
Externí odkaz:
https://doaj.org/article/e0834568d6a14e72bd3bd0eebf8b5aee
Autor:
Gavin Ha, Peter S. Nelson, Steven Henikoff, Eva Corey, R. Bruce Montgomery, Michael C. Haffner, Kami Ahmad, Matthew L. Freedman, Jacob E. Berchuck, Sylvan C. Baca, Atish D. Choudhury, Colm Morrissey, Michael T. Schweizer, Colin C. Pritchard, Heather M. McClure, Holly M. Nguyen, Talina A. Nunez, Jared M. Lucas, Ruth F. Dumpit, Arnab Bose, Ilsa M. Coleman, Lisa S. Ang, Derek H. Janssens, Michael P. Meers, Sandipan Brahma, Minjeong Ko, Jay F. Sarthy, Adam J. Kreitzman, Mohamed Adil, Brian Hanratty, Anna-Lisa Doebley, Robert D. Patton, Navonil De Sarkar
Feature-region combination AUCs and benchmarking Sheet 1: Log2 fold-change, p-value, and q-value between ARPC and NEPC lines for central mean coverage in all queried (338) TFs (two tailed Mann-Whitney U test, Benjamini-Hochberg adjusted). Sheet 2: 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131f41ff743e41934b8e4242f49253ae
https://doi.org/10.1158/2159-8290.22674256
https://doi.org/10.1158/2159-8290.22674256
Autor:
Gavin Ha, Peter S. Nelson, Steven Henikoff, Eva Corey, R. Bruce Montgomery, Michael C. Haffner, Kami Ahmad, Matthew L. Freedman, Jacob E. Berchuck, Sylvan C. Baca, Atish D. Choudhury, Colm Morrissey, Michael T. Schweizer, Colin C. Pritchard, Heather M. McClure, Holly M. Nguyen, Talina A. Nunez, Jared M. Lucas, Ruth F. Dumpit, Arnab Bose, Ilsa M. Coleman, Lisa S. Ang, Derek H. Janssens, Michael P. Meers, Sandipan Brahma, Minjeong Ko, Jay F. Sarthy, Adam J. Kreitzman, Mohamed Adil, Brian Hanratty, Anna-Lisa Doebley, Robert D. Patton, Navonil De Sarkar
Supplementary Figures S1-S18 and Supplementary Table legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a676746f9874d80588b96e87e41d0812
https://doi.org/10.1158/2159-8290.22674268.v1
https://doi.org/10.1158/2159-8290.22674268.v1
Autor:
Navonil De Sarkar, Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J. Kreitzman, Jay F. Sarthy, Minjeong Ko, Sandipan Brahma, Michael P. Meers, Derek H. Janssens, Lisa S. Ang, Ilsa M. Coleman, Arnab Bose, Ruth F. Dumpit, Jared M. Lucas, Talina A. Nunez, Holly M. Nguyen, Heather M. McClure, Colin C. Pritchard, Michael T. Schweizer, Colm Morrissey, Atish D. Choudhury, Sylvan C. Baca, Jacob E. Berchuck, Matthew L. Freedman, Kami Ahmad, Michael C. Haffner, R. Bruce Montgomery, Eva Corey, Steven Henikoff, Peter S. Nelson, Gavin Ha
Publikováno v:
Cancer discovery.
Advanced prostate cancers comprise distinct phenotypes, but tumor classification remains clinically challenging. Here, we harnessed circulating tumor DNA (ctDNA) to study tumor phenotypes by ascertaining nucleosome positioning patterns associated wit
Autor:
Mohamed Adil, Brian Hanratty, Pallabi Mustafi, Ilsa Coleman, Radhika Patel, Anna-Lisa Doebley, Robert Patton, Eden Cruikshank, Patricia Galipeau, Ruth Dumpit, Martine Roudier, Jin-Yih Low, Navonil De Sarkar, Robert Montgomery, Eva Corey, Colm Morrissey, Peter Nelson, Gavin Ha, Michael Haffner
Publikováno v:
Cancer Research. 83:LB298-LB298
Introduction: Metastatic castration-resistant prostate cancer (mCRPC) is a heterogeneous disease which can be classified into clinically relevant subtypes based on the expression of transcription factors (TF), such as the androgen receptor (AR) and n