Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Anna-Lena Scherr"'
Autor:
Nathalie Tisch, Carolin Mogler, Ana Stojanovic, Robert Luck, Emilia A Korhonen, Alexander Ellerkmann, Heike Adler, Mahak Singhal, Géza Schermann, Lena Erkert, Jay V Patankar, Andromachi Karakatsani, Anna‐Lena Scherr, Yaron Fuchs, Adelheid Cerwenka, Stefan Wirtz, Bruno Christian Köhler, Hellmut G Augustin, Christoph Becker, Thomas Schmidt, Carmen Ruiz de Almodóvar
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 6, Pp 1-21 (2022)
Abstract The gut has a specific vascular barrier that controls trafficking of antigens and microbiota into the bloodstream. However, the molecular mechanisms regulating the maintenance of this vascular barrier remain elusive. Here, we identified Casp
Externí odkaz:
https://doaj.org/article/9ef135c33a444c41ab1845d57c762be3
Autor:
Benjamin Sobol, Osama Azzam Nieto, Emily Lara Eberlein, Anna-Lena Scherr, Lars Ismail, Annika Kessler, Luisa Nader, Maximilian Schwab, Paula Hoffmeister, Nathalie Schmitt, Dirk Jäger, Stefan Welte, Katharina Seidensaal, Petros Christopoulos, Christoph Heilig, Katharina Kriegsmann, Stefan Fröhling, Mark Kriegsmann, Jochen Hess, Bruno Christian Köhler
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7850 (2022)
Avoidance of therapy-induced apoptosis is a hallmark of acquired resistance towards radiotherapy. Thus, breaking resistance still challenges modern cancer therapy. The Bcl-2 protein family is known for its regulatory role in apoptosis signaling, maki
Externí odkaz:
https://doaj.org/article/351421059448483faefafa495a63ef08
Autor:
Paula Hoffmeister‐Wittmann, Andreas Mock, Federico Nichetti, Felix Korell, Christoph E. Heilig, Anna‐Lena Scherr, Michael Günther, Thomas Albrecht, Eblina Kelmendi, Kaiyu Xu, Luisa Nader, Annika Kessler, Nathalie Schmitt, Sarah Fritzsche, Sofia Weiler, Benjamin Sobol, Albrecht Stenzinger, Stefan Boeck, Christoph B. Westphalen, Klaus Schulze‐Osthoff, Jörg Trojan, Thomas Kindler, Wilko Weichert, Karsten Spiekermann, Michael Bitzer, Gunnar Folprecht, Anna L. Illert, Melanie Boerries, Frederick Klauschen, Sebastian Ochsenreither, Jens Siveke, Sebastian Bauer, Hanno Glimm, Benedikt Brors, Jennifer Hüllein, Daniel Hübschmann, Sebastian Uhrig, Peter Horak, Simon Kreutzfeldt, Jesus M. Banales, Christoph Springfeld, Dirk Jäger, Peter Schirmacher, Stephanie Roessler, Steffen Ormanns, Benjamin Goeppert, Stefan Fröhling, Bruno C. Köhler
Publikováno v:
Liver International. 42:2855-2870
Intrahepatic, perihilar, and distal cholangiocarcinoma (iCCA, pCCA, dCCA) are highly malignant tumours with increasing mortality rates due to therapy resistances. Among the mechanisms mediating resistance, overexpression of anti-apoptotic Bcl-2 prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4e69096e2225653be02a227e6063dd
https://doi.org/10.1111/liv.15392
https://doi.org/10.1111/liv.15392
Autor:
Anna-Lena Scherr, Adam Jassowicz, Anna Pató, Christin Elssner, Lars Ismail, Nathalie Schmitt, Paula Hoffmeister, Lasse Neukirch, Georg Gdynia, Benjamin Goeppert, Henning Schulze-Bergkamen, Dirk Jäger, Bruno Christian Köhler
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1099 (2020)
Autophagy is a catabolic process that enables cells to degrade obsolete content and refuel energy depots. In colorectal cancer (CRC) autophagy has been shown to promote tumorigenesis through energy delivery in the condition of uncontrolled proliferat
Externí odkaz:
https://doaj.org/article/184b2af9530144e6940b3baf501aaa9e
Autor:
Paula, Hoffmeister-Wittmann, Andreas, Mock, Federico, Nichetti, Felix, Korell, Christoph E, Heilig, Anna-Lena, Scherr, Michael, Günther, Thomas, Albrecht, Eblina, Kelmendi, Kaiyu, Xu, Luisa, Nader, Annika, Kessler, Nathalie, Schmitt, Sarah, Fritzsche, Sofia, Weiler, Benjamin, Sobol, Albrecht, Stenzinger, Stefan, Boeck, Christoph B, Westphalen, Klaus, Schulze-Osthoff, Jörg, Trojan, Thomas, Kindler, Wilko, Weichert, Karsten, Spiekermann, Michael, Bitzer, Gunnar, Folprecht, Anna L, Illert, Melanie, Boerries, Frederick, Klauschen, Sebastian, Ochsenreither, Jens, Siveke, Sebastian, Bauer, Hanno, Glimm, Benedikt, Brors, Jennifer, Hüllein, Daniel, Hübschmann, Sebastian, Uhrig, Peter, Horak, Simon, Kreutzfeldt, Jesus M, Banales, Christoph, Springfeld, Dirk, Jäger, Peter, Schirmacher, Stephanie, Roessler, Steffen, Ormanns, Benjamin, Goeppert, Stefan, Fröhling, Bruno C, Köhler
Publikováno v:
Liver international : official journal of the International Association for the Study of the LiverREFERENCES. 42(12)
Intrahepatic, perihilar, and distal cholangiocarcinoma (iCCA, pCCA, dCCA) are highly malignant tumours with increasing mortality rates due to therapy resistances. Among the mechanisms mediating resistance, overexpression of anti-apoptotic Bcl-2 prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b7fa44cf02ea6112c9150a5f00b624f
https://pubmed.ncbi.nlm.nih.gov/35983950
https://pubmed.ncbi.nlm.nih.gov/35983950
Autor:
AnnikaSophia Keßler, Luisa Nader, Anna-Lena Scherr, Nathalie Schmitt, Kai Breuhahn, Sofia Weiler, Sarah Luiken, Stephanie Rössler, Ulrike Gärtner, Peter Schirmacher, Mathias Heikenwälder, Benjamin Goeppert, Dirk Jäger, BrunoChristian Köhler
Publikováno v:
Zeitschrift für Gastroenterologie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84d5125846335ee4ea0fe71d6c0bdab6
https://doi.org/10.1055/s-0041-1740770
https://doi.org/10.1055/s-0041-1740770
Autor:
Luisa Nader, Federico Nichetti, Anna-Lena Scherr, Christin Elssner, Dirk Ridder, Sarah Fritzsche, Sofia Weiler, Thomas Albrecht, Annika Kessler, Nathalie Schmitt, Felix Korell, Liangtao Ye, Toni Urbanik, Christoph Heilig, Mohammad Rahbari, Lydia Brandl, Christoph Springfeld, Thomas Longerich, Henning Schulze-Bergkamen, Dirk Jäger, Stefan Fröhling, Peter Schirmacher, Beate Straub, Achim Weber, Mathias Heikenwälder, Enrico de Toni, Benjamin Goeppert, Stephanie Roessler, Kai Breuhahn, Bruno Köhler
Publikováno v:
Journal of Hepatology. 77:S655-S656
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d521236ef5b2ae595d86124d17b3da82
https://doi.org/10.1016/s0168-8278(22)01628-2
https://doi.org/10.1016/s0168-8278(22)01628-2
Autor:
Bruno Christian Koehler, Anna-Lena Scherr, Stephan Lorenz, Christin Elssner, Nicole Kautz, Stefan Welte, Dirk Jaeger, Toni Urbanik, Henning Schulze-Bergkamen
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106571 (2014)
Despite the fact that new treatment regimes have improved overall survival of patients challenged by colorectal cancer (CRC), prognosis in the metastatic situation is still restricted. The Bcl-2 family of proteins has been identified as promising ant
Externí odkaz:
https://doaj.org/article/1f352e97a5ad487eb17326b147b8c202
Autor:
Bruno Christian Koehler, Anna-Lena Scherr, Stephan Lorenz, Toni Urbanik, Nicole Kautz, Christin Elssner, Stefan Welte, Justo Lorenzo Bermejo, Dirk Jäger, Henning Schulze-Bergkamen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76446 (2013)
Migration and invasion of malignant cells are prerequisites for cancer progression and metastasis. The Bcl-2 family of proteins consists of about 25 members and has been extensively studied in the context of apoptosis. Despite the fact that small mol
Externí odkaz:
https://doaj.org/article/a0299ed43f1f454c8794e21ee835a2df
Autor:
Henning Schulze-Bergkamen, Jens T. Siveke, Benedikt Brors, Dirk Jäger, Melanie Boerries, Oliver Waidmann, Philipp J. Jost, Benjamin Goeppert, Paula Hoffmeister, Peter Schirmacher, Klaus Schulze-Osthoff, Johanna Falkenhorst, Christoph E. Heilig, Stefan Fröhling, Jörg Trojan, Hanno Glimm, Michael Bitzer, Nathalie Schmitt, Andreas Mock, Klaus H. Metzeler, Bruno Köhler, Loredana Vecchione, Georg Gdynia, Tobias Gehrig, Ivan Jelas, Nisar P. Malek, Svetlana P Grekova, Anna Lena Illert, Praveen Rhadakrishnan, Felix Korell, Albrecht Stenzinger, Martin Schneider, Anna-Lena Scherr, Mathias Heikenwalder
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 10, Pp 1-16 (2020)
Cell Death and Disease, Vol 11, Iss 10, Pp 1-16 (2020)
Since metastatic colorectal cancer (CRC) is a leading cause of cancer-related death, therapeutic approaches overcoming primary and acquired therapy resistance are an urgent medical need. In this study, the efficacy and toxicity of high-affinity inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c028e0159dddff4eb087e5b9e4d8d01f
http://europepmc.org/articles/PMC7568722
http://europepmc.org/articles/PMC7568722