Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anna-Karin Johnsson"'
Autor:
Yitao Gong, Anna-Karin Johnsson, Jesper Säfholm, Mamdoh Al-Ameri, Erik Sachs, Kasra Vali, Gunnar Nilsson, Elin Rönnberg
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMast cells are critically involved in IgE-mediated diseases, e.g., allergies and asthma. Human mast cells are heterogeneous, and mast cells from different anatomical sites have been shown to respond differently to certain stimuli and drugs.
Externí odkaz:
https://doaj.org/article/61dd0c7e65ac475988e6a5ad6d7f8986
Autor:
Kirsti Hornigold, Martin J. Baker, Polly A. Machin, Stephen A. Chetwynd, Anna-Karin Johnsson, Chiara Pantarelli, Priota Islam, Melanie Stammers, Laraine Crossland, David Oxley, Hanneke Okkenhaug, Simon Walker, Rachael Walker, Anne Segonds-Pichon, Yoshinori Fukui, Angeliki Malliri, Heidi C. E. Welch
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Rac GTPases are required for neutrophil adhesion and migration, and for the neutrophil effector responses that kill pathogens. These Rac-dependent functions are impaired when neutrophils lack the activators of Rac, Rac-GEFs from the Prex, Vav, and Do
Externí odkaz:
https://doaj.org/article/63ffd6881b0f46df86c0a304a15b661a
Autor:
Vaishnavi Srinivasan Iyer, Sanjaykumar V. Boddul, Anna-Karin Johnsson, Bruno Raposo, Ravi K. Sharma, Yunbing Shen, Zsolt Kasza, Kah Wai Lim, Karine Chemin, Gunnar Nilsson, Vivianne Malmström, Anh Tuân Phan, Fredrik Wermeling
Publikováno v:
Journal of autoimmunity. 131
Dysregulated T-cell activation is a hallmark of several autoimmune diseases such as rheumatoid arthritis (RA) and multiple sclerosis (MS). The lymphocyte cytosolic protein 2 (LCP2), also known as SLP-76, is essential for the development and activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb3107c2d3c81f6c16fd42d7ed45c5b
https://pubmed.ncbi.nlm.nih.gov/35780036
https://pubmed.ncbi.nlm.nih.gov/35780036
Autor:
Craig E. Wheelock, Mikael Adner, Sven-Erik Dahlén, Anna-Karin Johnsson, Johan Kolmert, Javier Zurita, Jielu Liu, Gunnar Nilsson, Jesper Säfholm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07aae5995d21f9ade37287379388684c
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-454715
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-454715
Autor:
Johan Kolmert, Sven-Erik Dahlén, Gunnar Nilsson, Barbro Dahlén, David Fuchs, Mats Hamberg, Jeong-Hee Choi, Craig E. Wheelock, Elin Rönnberg, Anna-Karin Johnsson
Background The major mast cell prostanoid PGD(2) is targeted for therapy of asthma and other diseases, because the biological actions include bronchoconstriction, vasodilation and regulation of immune cells mediated by three different receptors. It i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0839c830974cf88ef069ab7247b72290
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-447453
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-447453
Autor:
Anna-Karin, Johnsson, Jeong-Hee, Choi, Elin, Rönnberg, David, Fuchs, Johan, Kolmert, Mats, Hamberg, Barbro, Dahlén, Craig E, Wheelock, Sven-Erik, Dahlén, Gunnar, Nilsson
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES. 51(4)
The major mast cell prostanoid PGDTo determine the biochemical consequences of inhibition of the hematopoietic prostaglandin D synthase (hPGDS) PGDFour human mast cell models, LAD2, cord blood derived mast cells (CBMC), peripheral blood derived mast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0665d278c1193b706acc4ff42a5f2c2c
https://pubmed.ncbi.nlm.nih.gov/33449404
https://pubmed.ncbi.nlm.nih.gov/33449404
Autor:
Barbro Dahlén, Sven-Erik Dahlén, Johan Kolmert, Gunnar Nilsson, Jeong-Hee Choi, David Fuchs, Mats Hamberg, Craig E. Wheelock, Elin Rönnberg, Anna-Karin Johnsson
Publikováno v:
Airway cell biology and immunopathology.
Background: The major mast cell prostanoid PGD2 is an interesting target for therapeutic intervention because of its influence on bronchoconstriction, vasodilation and eosinophilic recruitment. We investigated the biochemical impact of inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c59eff1692bf90d13ca9cc2496ac5353
https://doi.org/10.1183/13993003.congress-2020.627
https://doi.org/10.1183/13993003.congress-2020.627
Autor:
Mats Hamberg, David Fuchs, Anna-Karin Johnsson, Sven-Erik Dahlén, Xiao Tang, Craig E. Wheelock
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1865(4)
Trihydroxyoctadecenoic acids (TriHOMEs) are linoleic acid-derived lipid mediators reported to be dysregulated in obstructive lung disease. In contrast to many other oxylipins, TriHOME biosynthesis in humans is still poorly understood. The association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ded1c83c2da217fc58c5be14e43e99a
https://pubmed.ncbi.nlm.nih.gov/31918007
https://pubmed.ncbi.nlm.nih.gov/31918007
Autor:
Martijn L, Manson, Jesper, Säfholm, Anna, James, Anna-Karin, Johnsson, Per, Bergman, Mamdoh, Al-Ameri, Ann-Charlotte, Orre, Carina, Kärrman-Mårdh, Sven-Erik, Dahlén, Mikael, Adner
Publikováno v:
The Journal of allergy and clinical immunology. 145(3)
Specific inflammatory pathways are indicated to contribute to severe asthma, but their individual involvement in the development of airway hyperresponsiveness remains unexplored.This experimental study in human small bronchi aimed to provide insight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1518be51a3be65c5370459df5eee8f1e
https://pubmed.ncbi.nlm.nih.gov/31805312
https://pubmed.ncbi.nlm.nih.gov/31805312
Autor:
Elin Rönnberg, Gunnar Nilsson, Hans-Erik Claesson, Mats Hamberg, Johan Kolmert, Craig E. Wheelock, Anna-Karin Johnsson, Sven-Erik Dahlén, Jesper Säfholm, David Fuchs
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1866:158886
15-hydroxyeicosatetraenoic acid (15-HETE) is an arachidonic acid derived lipid mediator which can originate both from 15-lipoxygenase (15-LOX) activity and cyclooxygenase (COX) activity. The enzymatic source determines the enantiomeric profile of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87348d85f203463622b1a1d4fd362ae9
https://doi.org/10.1016/j.bbalip.2021.158886
https://doi.org/10.1016/j.bbalip.2021.158886