Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anna di Maio"'
Autor:
Alberto Imarisio, Isar Yahyavi, Clara Gasparri, Amber Hassan, Micol Avenali, Anna Di Maio, Gabriele Buongarzone, Caterina Galandra, Marta Picascia, Asia Filosa, Maria Cristina Monti, Claudio Pacchetti, Francesco Errico, Mariangela Rondanelli, Alessandro Usiello, Enza Maria Valente
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Frailty is a common age-related clinical syndrome characterized by a decline in the function of multiple organ systems, increased vulnerability to stressors, and a huge socio-economic burden. Despite recent research efforts, the physiopathol
Externí odkaz:
https://doaj.org/article/e4a0fd0eec5047e09feecd3b351ffc47
Autor:
Alberto Imarisio, Isar Yahyavi, Micol Avenali, Anna Di Maio, Gabriele Buongarzone, Caterina Galandra, Marta Picascia, Asia Filosa, Clara Gasparri, Maria Cristina Monti, Mariangela Rondanelli, Claudio Pacchetti, Francesco Errico, Enza Maria Valente, Alessandro Usiello
Publikováno v:
Neurobiology of Disease, Vol 192, Iss , Pp 106413- (2024)
We recently described increased D- and L-serine concentrations in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated monkeys, the post-mortem caudate-putamen of human Parkinson's disease (PD) brains and the cerebrospinal flui
Externí odkaz:
https://doaj.org/article/c2a75f8d8b7541e4b2e1c288a5fe93da
Autor:
Anna Di Maio, Tommaso Nuzzo, Luana Gilio, Marcello Serra, Fabio Buttari, Francesco Errico, Arianna De Rosa, Mario Stampanoni Bassi, Micaela Morelli, Jumpei Sasabe, David Sulzer, Manolo Carta, Diego Centonze, Alessandro Usiello
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106203- (2023)
L-serine generated in astrocytes plays a pivotal role in modulating essential neurometabolic processes, while its enantiomer, D-serine, specifically regulates NMDA receptor (NMDAR) signalling. Despite their physiological relevance in modulating cereb
Externí odkaz:
https://doaj.org/article/e7518a3495a0499ea6ecba49a65a421f
Autor:
Marcello Serra, Anna Di Maio, Valentina Bassareo, Tommaso Nuzzo, Francesco Errico, Federica Servillo, Mario Capasso, Pathik Parekh, Qin Li, Marie-Laure Thiolat, Erwan Bezard, Paolo Calabresi, David Sulzer, Manolo Carta, Micaela Morelli, Alessandro Usiello
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106226- (2023)
Loss of dopaminergic midbrain neurons perturbs l-serine and d-serine homeostasis in the post-mortem caudate putamen (CPu) of Parkinson's disease (PD) patients. However, it is unclear whether the severity of dopaminergic nigrostriatal degeneration pla
Externí odkaz:
https://doaj.org/article/32f6acc0b6824302a2510d94ba1684ce
Autor:
Barbara Lombardo, Marco Pagani, Arianna De Rosa, Marcella Nunziato, Sara Migliarini, Martina Garofalo, Marta Terrile, Valeria D’Argenio, Alberto Galbusera, Tommaso Nuzzo, Annaluisa Ranieri, Andrea Vitale, Eleonora Leggiero, Anna Di Maio, Noemi Barsotti, Ugo Borello, Francesco Napolitano, Alessandra Mandarino, Marco Carotenuto, Uriel Heresco-Levy, Massimo Pasqualetti, Paolo Malatesta, Alessandro Gozzi, Francesco Errico, Francesco Salvatore, Lucio Pastore, Alessandro Usiello
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The D-aspartate oxidase (DDO) gene encodes the enzyme responsible for the catabolism of D-aspartate, an atypical amino acid enriched in the mammalian brain and acting as an endogenous NMDA receptor agonist. Considering the key role of NMDA r
Externí odkaz:
https://doaj.org/article/7e8f008da6d942f7b332be344650f0ca
Autor:
Arianna De Rosa, Andrea Fontana, Tommaso Nuzzo, Martina Garofalo, Anna Di Maio, Daniela Punzo, Massimiliano Copetti, Alessandro Bertolino, Francesco Errico, Antonio Rampino, Andrea de Bartolomeis, Alessandro Usiello
Publikováno v:
npj Schizophrenia, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Schizophrenia is a disorder of synaptic plasticity and aberrant connectivity in which a major dysfunction in glutamate synapse has been suggested. However, a multi-level approach tackling diverse clusters of interacting molecules of the glut
Externí odkaz:
https://doaj.org/article/423273751e00441c99b6458e7c36ec5d
Autor:
Alessandra Santillo, Sara Falvo, Massimo Venditti, Anna Di Maio, Gabriella Chieffi Baccari, Francesco Errico, Alessandro Usiello, Sergio Minucci, Maria Maddalena Di Fiore
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 621 (2023)
High levels of free D-aspartate (D-Asp) are present in vertebrate testis during post-natal development, coinciding with the onset of testosterone production, which suggests that this atypical amino acid might participate in the regulation of hormone
Externí odkaz:
https://doaj.org/article/87889bd89c4f4d259ca20d2459e33c49
Autor:
Valeria Calabrese, Anna Di Maio, Gioia Marino, Antonella Cardinale, Giuseppina Natale, Arianna De Rosa, Federica Campanelli, Maria Mancini, Francesco Napolitano, Luigi Avallone, Paolo Calabresi, Alessandro Usiello, Veronica Ghiglieri, Barbara Picconi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Levodopa (L-DOPA) treatment is the main gold-standard therapy for Parkinson disease (PD). Besides good antiparkinsonian effects, prolonged use of this drug is associated to the development of involuntary movements known as L-DOPA-induced dyskinesia (
Externí odkaz:
https://doaj.org/article/a7602896de9f424fb37861e0572fc994
Autor:
Arianna De Rosa, Anna Di Maio, Silvia Torretta, Martina Garofalo, Valentina Giorgelli, Rita Masellis, Tommaso Nuzzo, Francesco Errico, Alessandro Bertolino, Srinivasa Subramaniam, Antonio Rampino, Alessandro Usiello
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 328 (2022)
Schizophrenia (SCZ) is a polygenic severe mental illness. Genome-wide association studies (GWAS) have detected genomic variants associated with this psychiatric disorder and pathway analyses have indicated immune system and dopamine signaling as core
Externí odkaz:
https://doaj.org/article/56af75136a2c4348a66b67646af0b06d
Autor:
Veronica Ghiglieri, Desiree Mineo, Anna Vannelli, Fabrizio Cacace, Maria Mancini, Valentina Pendolino, Francesco Napolitano, Anna di Maio, Manuela Mellone, Jennifer Stanic, Elisabetta Tronci, Camino Fidalgo, Roberto Stancampiano, Manolo Carta, Paolo Calabresi, Fabrizio Gardoni, Alessandro Usiello, Barbara Picconi
Publikováno v:
Neurobiology of Disease, Vol 86, Iss , Pp 140-153 (2016)
ABSTRACT: L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesias (LIDs) represent the main side effect of Parkinson's Disease (PD) therapy. Among the various pharmacological targets for novel therapeutic approaches, the serotonergic system represe
Externí odkaz:
https://doaj.org/article/0397c891116e432fb21a3efb279c3141