Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Anna Zakrzewicz"'
Autor:
Rüdiger Eming, Shafaq Riaz, Eliane J. Müller, Anna Zakrzewicz, Uwe Linne, Ritva Tikkanen, Christine Lea Zimmer, Christoph Hudemann
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPemphigus vulgaris (PV) is a life-threatening autoimmune blistering disease caused mainly by IgG autoantibodies (auto-abs) against the cadherin-type adhesion molecules desmoglein (Dsg) 1 and 3. Pathogenic anti-Dsg3 auto-abs bind to differen
Externí odkaz:
https://doaj.org/article/fc4c68ae268a4302bf6d374557b1fd0b
Autor:
Anna Zakrzewicz, Katrien Vanderheyden, Yad Galaly, Simon Feldhoff, Magdalena Sips, Maximilian Brinkhaus, Ritva Tikkanen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The neonatal Fc receptor (FcRn) is important for numerous cellular processes that involve antibody recycling and trafficking. A major function of FcRn is IgG recycling and half-life prolongation, and FcRn blockade results in a reduction of autoantibo
Externí odkaz:
https://doaj.org/article/d8db3bf2f6a64a55929016d2d491384e
Autor:
Katrin Richter, Nilay Asci, Vijay K. Singh, Sanaria Hawro Yakoob, Marion Meixner, Anna Zakrzewicz, Juliane Liese, Andreas Hecker, Sigrid Wilker, Sabine Stumpf, Klaus-Dieter Schlüter, Marius Rohde, Axel Gödecke, Winfried Padberg, Ivan Manzini, Günther Schmalzing, Veronika Grau
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveThe pro-inflammatory cytokine interleukin-1β (IL-1β) plays a central role in host defense against infections. High systemic IL-1β levels, however, promote the pathogenesis of inflammatory disorders. Therefore, mechanisms controlling IL-1
Externí odkaz:
https://doaj.org/article/fe2b859d229d40228c40c22e250675d2
Autor:
Anna Zakrzewicz, Celina Würth, Benedikt Beckert, Simon Feldhoff, Katrien Vanderheyden, Stian Foss, Jan Terje Andersen, Hans de Haard, Peter Verheesen, Vladimir Bobkov, Ritva Tikkanen
Publikováno v:
Cells, Vol 11, Iss 10, p 1700 (2022)
The authors wish to make the following changes to their paper [...]
Externí odkaz:
https://doaj.org/article/61896ac700a94631a0d52eeb793152df
Autor:
Anna Zakrzewicz, Celina Würth, Benedikt Beckert, Simon Feldhoff, Katrien Vanderheyden, Stian Foss, Jan Terje Andersen, Hans de Haard, Peter Verheesen, Vladimir Bobkov, Ritva Tikkanen
Publikováno v:
Cells, Vol 11, Iss 6, p 942 (2022)
Pemphigus vulgaris is an autoimmune blistering disease of the epidermis, caused by autoantibodies against desmosomal proteins, mainly desmogleins 1 and 3, which induce an impairment of desmosomal adhesion and blister formation. Recent findings have s
Externí odkaz:
https://doaj.org/article/94bff078217b4747b791e79e694256c3
Publikováno v:
Cells, Vol 10, Iss 5, p 1259 (2021)
Recombinant adeno-associated viruses (AAV) have emerged as an important tool for gene therapy for human diseases. A prerequisite for clinical approval is an in vitro potency assay that can measure the transduction efficiency of each virus lot produce
Externí odkaz:
https://doaj.org/article/bec499d86e1941a0a9d3a19f91cb3aae
Autor:
Sören Backhaus, Anna Zakrzewicz, Katrin Richter, Jelena Damm, Sigrid Wilker, Gabriele Fuchs-Moll, Mira Küllmar, Andreas Hecker, Ivan Manzini, Clemens Ruppert, J. Michael McIntosh, Winfried Padberg, Veronika Grau
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1055-1066 (2017)
Interleukin (IL)-1β is a potent pro-inflammatory cytokine of innate immunity involved in host defense. High systemic IL-1β levels, however, cause life-threatening inflammatory diseases, including systemic inflammatory response syndrome. In response
Externí odkaz:
https://doaj.org/article/5cc171bf15eb41cc99e34af7be83f92e
Autor:
Anna Zakrzewicz, Katrin Richter, Dariusz Zakrzewicz, Kathrin Siebers, Jelena Damm, Alisa Agné, Andreas Hecker, J. Michael McIntosh, Walee Chamulitrat, Gabriela Krasteva-Christ, Ivan Manzini, Ritva Tikkanen, Winfried Padberg, Sabina Janciauskiene, Veronika Grau
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Interleukin-1β (IL-1β) is a potent, pro-inflammatory cytokine of the innate immune system that plays an essential role in host defense against infection. However, elevated circulating levels of IL-1β can cause life-threatening systemic inflammatio
Externí odkaz:
https://doaj.org/article/33801e27ed7e46ef8dc4ae7bde9ee513
Autor:
Kathrin Siebers, Bijan Fink, Anna Zakrzewicz, Alisa Agné, Katrin Richter, Sebastian Konzok, Andreas Hecker, Sven Zukunft, Mira Küllmar, Jochen Klein, J. Michael McIntosh, Thomas Timm, Katherina Sewald, Winfried Padberg, Nupur Aggarwal, Walee Chamulitrat, Sentot Santoso, Wendy Xia, Sabina Janciauskiene, Veronika Grau
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
While interleukin (IL)-1β is a potent pro-inflammatory cytokine involved in host defense, high levels can cause life-threatening sterile inflammation including systemic inflammatory response syndrome. Hence, the control of IL-1β secretion is of out
Externí odkaz:
https://doaj.org/article/8aee939e5b6440529da192d7c266b918
Autor:
Anna Zakrzewicz, Katrin Richter, Alisa Agné, Sigrid Wilker, Kathrin Siebers, Bijan Fink, Gabriela Krasteva-Christ, Mike Althaus, Winfried Padberg, Arik J. Hone, J. Michael McIntosh, Veronika Grau
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Recently, we discovered a cholinergic mechanism that inhibits the adenosine triphosphate (ATP)-dependent release of interleukin-1β (IL-1β) by human monocytes via nicotinic acetylcholine receptors (nAChRs) composed of α7, α9 and/or α10 subunits.
Externí odkaz:
https://doaj.org/article/8e2a590967604fde86262405c8b26c54