Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Anna Z Mykytyn"'
Autor:
Maitrayee Chatterjee, Liane Z X Huang, Anna Z Mykytyn, Chunyan Wang, Mart M Lamers, Bart Westendorp, Richard W Wubbolts, Jos P M van Putten, Berend-Jan Bosch, Bart L Haagmans, Karin Strijbis
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011571 (2023)
Mucins play an essential role in protecting the respiratory tract against microbial infections while also acting as binding sites for bacterial and viral adhesins. The heavily O-glycosylated gel-forming mucins MUC5AC and MUC5B eliminate pathogens by
Externí odkaz:
https://doaj.org/article/5c8ab95199664948ba87d8d4e698b857
Autor:
Mart M Lamers, Anna Z Mykytyn, Tim I Breugem, Yiquan Wang, Douglas C Wu, Samra Riesebosch, Petra B van den Doel, Debby Schipper, Theo Bestebroer, Nicholas C Wu, Bart L Haagmans
Publikováno v:
eLife, Vol 10 (2021)
Virus propagation methods generally use transformed cell lines to grow viruses from clinical specimens, which may force viruses to rapidly adapt to cell culture conditions, a process facilitated by high viral mutation rates. Upon propagation in VeroE
Externí odkaz:
https://doaj.org/article/3d0c2b13478f4404ae22e956acd8b062
Autor:
Anna Z Mykytyn, Tim I Breugem, Samra Riesebosch, Debby Schipper, Petra B van den Doel, Robbert J Rottier, Mart M Lamers, Bart L Haagmans
Publikováno v:
eLife, Vol 10 (2021)
Coronavirus entry is mediated by the spike protein that binds the receptor and mediates fusion after cleavage by host proteases. The proteases that mediate entry differ between cell lines, and it is currently unclear which proteases are relevant in v
Externí odkaz:
https://doaj.org/article/bff5e7cfb4864de5a79908ccfb16e14b
Autor:
Tim I. Breugem, Samra Riesebosch, Debby Schipper, Anna Z. Mykytyn, Petra van den Doel, Joaquim Segalés, Mart M. Lamers, Bart L. Haagmans
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-8 (2024)
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects a variety of animal species. Susceptibility to SARS-CoV-2 is primarily determined by the utilization of the viral receptor, ACE2. SARS-CoV-2 can utilize a broad range o
Externí odkaz:
https://doaj.org/article/59da96f1d6094a34b9e2ae01117cd1fb
Autor:
Franziska K. Kaiser, Mariana Gonzalez Hernandez, Nadine Krüger, Ellinor Englund, Wenjuan Du, Anna Z. Mykytyn, Mathijs P. Raadsen, Mart M. Lamers, Francine Rodrigues Ianiski, Tatiana M. Shamorkina, Joost Snijder, Federico Armando, Georg Beythien, Malgorzata Ciurkiewicz, Tom Schreiner, Eva Gruber-Dujardin, Martina Bleyer, Olga Batura, Lena Erffmeier, Rabea Hinkel, Cheila Rocha, Monica Mirolo, Dubravka Drabek, Berend-Jan Bosch, Mark Emalfarb, Noelia Valbuena, Ronen Tchelet, Wolfgang Baumgärtner, Markku Saloheimo, Stefan Pöhlmann, Frank Grosveld, Bart L. Haagmans, Albert D.M.E. Osterhaus
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Monoclonal antibodies are an increasingly important tool for prophylaxis and treatment of acute virus infections like SARS-CoV-2 infection. However, their use is often restricted due to the time required for development, variable yields and
Externí odkaz:
https://doaj.org/article/98f6041d164849c48be914ce65c5b198
Autor:
Pau Ribó-Molina, Stefan van Nieuwkoop, Anna Z. Mykytyn, Peter van Run, Mart M. Lamers, Bart L. Haagmans, Ron A. M. Fouchier, Bernadette G. van den Hoogen
Publikováno v:
mSphere, Vol 9, Iss 2 (2024)
ABSTRACT Human metapneumovirus (HMPV), a member of the Pneumoviridae family, causes upper and lower respiratory tract infections in humans. In vitro studies with HMPV have mostly been performed in monolayers of undifferentiated epithelial cells. In v
Externí odkaz:
https://doaj.org/article/150b610fc37748a297daaac8a658e4b1
Autor:
Joep Beumer, Maarten H. Geurts, Mart M. Lamers, Jens Puschhof, Jingshu Zhang, Jelte van der Vaart, Anna Z. Mykytyn, Tim I. Breugem, Samra Riesebosch, Debby Schipper, Petra B. van den Doel, Wim de Lau, Cayetano Pleguezuelos-Manzano, Georg Busslinger, Bart L. Haagmans, Hans Clevers
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Rapid identification of host genes essential for virus replication may expedite the generation of therapeutic interventions. Here the authors generate mutant clonal intestinal organoids for 19 host genes previously implicated in coronavirus biology a
Externí odkaz:
https://doaj.org/article/1db487b66712463886d067b96ac47dba
Autor:
Anna Z. Mykytyn, Mart M. Lamers, Nisreen M. A. Okba, Tim I. Breugem, Debby Schipper, Petra B. van den Doel, Peter van Run, Geert van Amerongen, Leon de Waal, Marion P. G. Koopmans, Koert J. Stittelaar, Judith M. A. van den Brand, Bart L. Haagmans
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 1-7 (2021)
Transmission of severe acute respiratory coronavirus-2 (SARS-CoV-2) between livestock and humans is a potential public health concern. We demonstrate the susceptibility of rabbits to SARS-CoV-2, which excrete infectious virus from the nose and throat
Externí odkaz:
https://doaj.org/article/4b61bf5040ed4babadbf6f5822b71e13
Autor:
Anna Z Mykytyn, Miruna E Rosu, Adinda Kok, Melanie Rissmann, Geert van Amerongen, Corine Geurtsvankessel, Rory D de Vries, Bas B Oude Munnink, Derek J Smith, Marion P G Koopmans, Mart M Lamers, Ron A M Fouchier, Bart L Haagmans
Publikováno v:
The Lancet Microbe, 4(5), e294-e295. Elsevier Ltd.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814f4cc761c151b6e1b9f06b46728823
https://pure.eur.nl/en/publications/fd0d3626-b1aa-439f-be99-53e0a2b7aa48
https://pure.eur.nl/en/publications/fd0d3626-b1aa-439f-be99-53e0a2b7aa48
Autor:
Carlijn C E Jordans, Anna Z Mykytyn, Eric C. M. van Gorp, Mart M. Lamers, Corine H. GeurtsvanKessel, Matthijs P. Raadsen, Arvind Gharbharan, Bart J. A. Rijnders, Bart L. Haagmans, Johannes P. C. van den Akker, Petra B. van den Doel, Henrik Endeman, Marco Goeijenbier, Marion Koopmans, Casper Rokx
Publikováno v:
Journal of Clinical Immunology
Journal of Clinical Immunology, 42(2), 232-239. Springer New York
Journal of Clinical Immunology, 42(2), 232-239. Springer New York
Purpose To study the effect of interferon-α2 auto-antibodies (IFN-α2 Abs) on clinical and virological outcomes in critically ill COVID-19 patients and the risk of IFN-α2 Abs transfer during convalescent plasma treatment. Methods Sera from healthy