Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Anna Yu. Spivak"'
Autor:
Mikhail V. Dubinin, Darya A. Nedopekina, Anna I. Ilzorkina, Alena A. Semenova, Vyacheslav A. Sharapov, Eldar V. Davletshin, Natalia V. Mikina, Yuri P. Belsky, Anna Yu. Spivak, Vladimir S. Akatov, Natalia V. Belosludtseva, Jiankang Liu, Konstantin N. Belosludtsev
Publikováno v:
Membranes, Vol 13, Iss 6, p 563 (2023)
The present work shows the cytotoxic effects of novel conjugates of ursolic, oleanolic, maslinic, and corosolic acids with the penetrating cation F16 on cancer cells (lung adenocarcinoma A549 and H1299, breast cancer cell lines MCF-7 and BT474) and n
Externí odkaz:
https://doaj.org/article/e339fd2e58c7473da384490b7ffb9826
Autor:
Anna Yu. Spivak, Darya A. Nedopekina, Zulfiya R. Galimshina, Rezeda R. Khalitova, Zarema R. Sadretdinova, Rinat R. Gubaidullin, Victor N. Odinokov
Publikováno v:
ARKIVOC, Vol 2018, Iss 7, Pp 1-19 (2018)
Externí odkaz:
https://doaj.org/article/7725cf7e508a43a997f5e28c80e478b7
Autor:
Rinat R. Gubaidullin, Darina S. Yarmukhametova, Darya A. Nedopekina, Rezeda R. Khalitova, Anna Yu. Spivak
Publikováno v:
ARKIVOC, Vol 2017, Iss 5, Pp 100-116 (2017)
Externí odkaz:
https://doaj.org/article/5e50f6dad0f54f3e98fb64e09ee1ca34
Autor:
Mikhail V. Dubinin, Alena A. Semenova, Darya A. Nedopekina, Eldar V. Davletshin, Anna Yu. Spivak, Konstantin N. Belosludtsev
Publikováno v:
Membranes, Vol 11, Iss 5, p 352 (2021)
This work demonstrates the effects of a newly synthesized conjugate of the plant triterpenoid betulin and the penetrating cation F16 used for mitochondrial targeting. The resulting F16-betulin conjugate revealed a mitochondria-targeted effect, decrea
Externí odkaz:
https://doaj.org/article/858a1a5832f24a6fb636b50da2395e68
Publikováno v:
ARKIVOC, Vol 2011, Iss 8, Pp 67-75 (2011)
Externí odkaz:
https://doaj.org/article/f0b7a5f5d7cb48f6b8e7f78c0a2548d7
Autor:
Victor N. Odinokov, Anna Yu. Spivak, Gulnara A. Emelyanova, Marina I. Mallyabaeva, Oksana V. Nazarova, Usein M. Dzhemilev
Publikováno v:
ARKIVOC, Vol 2003, Iss 13, Pp 101-118 (2003)
Externí odkaz:
https://doaj.org/article/6f8d9116d57e46088c20ff6b9a6f54a8
Publikováno v:
ChemistrySelect. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f98f0debf81836e8d7919db4dfabd423
https://doi.org/10.1002/slct.202202241
https://doi.org/10.1002/slct.202202241
Autor:
Eldar V. Davletshin, A.A. Tukhbatullin, Rinat R. Gubaidullin, Anna Yu. Spivak, Lilya U. Dzhemileva, Darya A. Nedopekina, Vladimir A. D’yakonov, Milyausha M. Yunusbaeva, Usein M. Dzhemilev
Publikováno v:
Medicinal Chemistry Research. 30:940-951
The first representatives of F16-conjugated pentacyclic triterpenoids, betulin and betulinic, ursolic, oleanolic, and glycyrrhetic acid derivatives, were synthesized. The triterpene core was linked, at the С-3, С-28, or С-30 position, to one or tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05a9187a5ea984d4db22e1319eb2f4ca
https://doi.org/10.1007/s00044-021-02702-z
https://doi.org/10.1007/s00044-021-02702-z
Autor:
Konstantin N. Belosludtsev, Anna I. Ilzorkina, Natalia V. Belosludtseva, Vyacheslav A. Sharapov, Nikita V. Penkov, Dmitriy A. Serov, Maxim N. Karagyaur, Darya A. Nedopekina, Eldar V. Davletshin, Marina E. Solovieva, Anna Yu Spivak, Ulyana Sh. Kuzmina, Yulia V. Vakhitova, Vladimir S. Akatov, Mikhail V. Dubinin
Publikováno v:
Biomedicines; Volume 10; Issue 11; Pages: 2903
The present study evaluates the cytotoxicity of a previously synthesized conjugate of betulinic acid (BA) with the penetrating cation F16 on breast adenocarcinoma (MCF-7) and human fibroblast (HF) cell lines, and also shows the mechanism underlying i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a016ebdaf9365de66f68071f9e100f
https://doi.org/10.3390/biomedicines10112903
https://doi.org/10.3390/biomedicines10112903
Autor:
Anna I. Ilzorkina, Mikhail V. Dubinin, Eldar V. Davletshin, Nikita V. Penkov, Vyacheslav A. Sharapov, Konstantin N. Belosludtsev, Natalia V. Belosludtseva, Anna Yu. Spivak, Alena A. Semenova, E. I. Khoroshavina, Darya A. Nedopekina
Publikováno v:
Free radical biologymedicine. 168
The paper examines the molecular mechanisms of the cytotoxicity of conjugates of betulinic acid with the penetrating cation F16. The in vitro experiments on rat thymocytes revealed that all the obtained F16-betulinic acid derivatives showed more than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cb98c4afe29c49d51f307f4e953869
https://pubmed.ncbi.nlm.nih.gov/33812008
https://pubmed.ncbi.nlm.nih.gov/33812008