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Akademický článek

Cyanine 5.5 conjugated nanobubbles as a tumor selective contrast agent for dual ultrasound-fluorescence imaging in a mouse model.

Autor: Liyi Mai, Anna Yao, Jing Li, Qiong Wei, Ming Yuchi, Xiaoling He, Mingyue Ding, Qibing Zhou

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e61224 (2013)

Nanobubbles and microbubbles are non-invasive ultrasound imaging contrast agents that may potentially enhance diagnosis of tumors. However, to date, both nanobubbles and microbubbles display poor in vivo tumor-selectivity over non-targeted organs suc

Externí odkaz: https://doaj.org/article/7da913f31f61408d8d4d1793d1b4ced9

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Akademický článek

Design, synthesis, and in vitro and in vivo biological studies of a 3'-deoxythymidine conjugate that potentially kills cancer cells selectively.

Autor: Qiong Wei, Dejun Zhang, Anna Yao, Liyi Mai, Zhiwei Zhang, Qibing Zhou

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e52199 (2012)

Thymidine kinases (TKs) have been considered one of the potential targets for anticancer therapeutic because of their elevated expressions in cancer cells. However, nucleobase analogs targeting TKs have shown poor selective cytotoxicity in cancer cel

Externí odkaz: https://doaj.org/article/babd5b7f78bc4f668f82ab6fc25d3b7f

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