Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anna Y, Aksenova"'
Autor:
Anna S. Zhuk, Elena I. Stepchenkova, Irina V. Zotova, Olesya B. Belopolskaya, Youri I. Pavlov, Ivan I. Kostroma, Sergey V. Gritsaev, Anna Y. Aksenova
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5269 (2024)
Multiple myeloma (MM) is the second most common hematological malignancy, which remains incurable despite recent advances in treatment strategies. Like other forms of cancer, MM is characterized by genomic instability, caused by defects in DNA repair
Externí odkaz:
https://doaj.org/article/dc61a59ebfce44c3997b15f8968d0d59
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11960 (2023)
The yeast S. cerevisiae is a unique genetic object for which a wide range of relatively simple, inexpensive, and non-time-consuming methods have been developed that allow the performing of a wide variety of genome modifications. Among the latter, one
Externí odkaz:
https://doaj.org/article/acbdb5489c0c48dfb4d2753879889672
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13502 (2022)
SARS-CoV-2 is a rapidly evolving pathogen that has caused a global pandemic characterized by several consecutive waves. Based on epidemiological and NGS data, many different variants of SARS-CoV-2 were described and characterized since the original v
Externí odkaz:
https://doaj.org/article/ff5761c26e024d02af9513f43034a907
Autor:
Daniel V. Kachkin, Kirill V. Volkov, Julia V. Sopova, Alexander G. Bobylev, Sergei A. Fedotov, Sergei G. Inge-Vechtomov, Oxana V. Galzitskaya, Yury O. Chernoff, Aleksandr A. Rubel, Anna Y. Aksenova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11657 (2022)
RAD51 is a central protein of homologous recombination and DNA repair processes that maintains genome stability and ensures the accurate repair of double-stranded breaks (DSBs). In this work, we assessed amyloid properties of RAD51 in vitro and in th
Externí odkaz:
https://doaj.org/article/7fefa267ef5c45c699b4d307962d020f
Autor:
Ryan J. McGinty, Franco Puleo, Anna Y. Aksenova, Julia A. Hisey, Alexander A. Shishkin, Erika L. Pearson, Eric T. Wang, David E. Housman, Claire Moore, Sergei M. Mirkin
Publikováno v:
Cell Reports, Vol 20, Iss 10, Pp 2490-2500 (2017)
Expansions of microsatellite repeats are responsible for numerous hereditary diseases in humans, including myotonic dystrophy and Friedreich’s ataxia. Whereas the length of an expandable repeat is the main factor determining disease inheritance, re
Externí odkaz:
https://doaj.org/article/0dfcf17ded7242c7a59c4d6e7f1ea13e
Publikováno v:
Cell Reports, Vol 13, Iss 8, Pp 1545-1551 (2015)
Telomeric repeats located within chromosomes are called interstitial telomeric sequences (ITSs). They are polymorphic in length and are likely hotspots for initiation of chromosomal rearrangements that have been linked to human disease. Using our S.
Externí odkaz:
https://doaj.org/article/a31c71a4dcdf4b5da45f34562c496a10
Autor:
Elina A Radchenko, Anna Y Aksenova, Kirill V Volkov, Alexander A Shishkin, Youri I Pavlov, Sergei M Mirkin
Publikováno v:
PNAS nexus. 1(3)
In humans, telomeric repeats (TTAGGG)n are known to be present at internal chromosomal sites. These interstitial telomeric sequences (ITSs) are an important source of genomic instability, including repeat length polymorphism, but the molecular mechan
Autor:
Anna Y. Aksenova
Publikováno v:
Ecological genetics. 18:135-138
COVID-19 caused by the SARS-CoV-2 virus is a new type of infection which has caused an enormous social and economic burden across the world. While most people will develop a mild-to-moderate form of the disease or even stay asymptomatic, a certain pr
Autor:
Anna S. Zhuk, Irina V. Zotova, Youri I. Pavlov, Anna Y. Aksenova, Ivan Ivanovich Kostroma, Artem G. Lada, S.V. Gritsaev, Elena I. Stepchenkova
Publikováno v:
Cancers
Cancers, Vol 13, Iss 5949, p 5949 (2021)
Cancers, Vol 13, Iss 5949, p 5949 (2021)
Simple Summary Multiple myeloma is an incurable blood cancer caused by the malignant transformation of immunoglobulin-producing plasma cells. The mechanisms leading to the origin of cancerous cells and the evolution of myeloma disease are not underst
Autor:
Franco Puleo, Anna Y. Aksenova, Claire Moore, Julia A. Hisey, David E. Housman, Sergei M. Mirkin, Erika L. Pearson, Ryan J. McGinty, Eric T. Wang, Alexander A. Shishkin
Publikováno v:
Cell Reports, Vol 20, Iss 10, Pp 2490-2500 (2017)
Expansions of microsatellite repeats are responsible for numerous hereditary diseases in humans, including myotonic dystrophy and Friedreich’s ataxia. While the length of an expandable repeat is the main factor determining disease inheritance, rece