Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Anna Wilkaniec"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Parkinson’s disease (PD) and other synucleinopathies are characterized by the aggregation and deposition of alpha-synuclein (α-syn) in brain cells, forming insoluble inclusions such as Lewy bodies (LBs) and Lewy neurites (LNs). The aggregation of
Externí odkaz:
https://doaj.org/article/7f8789cf8e944d3cb3893e93a58ccfd1
Autor:
Grażyna Gromadzka, Anna Wilkaniec, Beata Tarnacka, Krzysztof Hadrian, Maria Bendykowska, Adam Przybyłkowski, Tomasz Litwin
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7545 (2024)
Wilson’s disease (WD) is inherited in an autosomal recessive manner and is caused by pathogenic variants of the ATP7B gene, which are responsible for impaired copper transport in the cell, inhibition of copper binding to apoceruloplasmin, and bilia
Externí odkaz:
https://doaj.org/article/eca39a27d80148e088d2760d0d0a26f9
Publikováno v:
Folia Neuropathologica, Vol 60, Iss 4, Pp 390-402 (2022)
Purinergic signalling is involved in the control of several processes related to brain development, such as neurogenesis and gliogenesis, migration and differentiation of neuronal precursors, synaptogenesis and synaptic elimination to achieve a fully
Externí odkaz:
https://doaj.org/article/218e33e0003e4630a2adc54eb9ae7308
Autor:
Lidia Babiec, Anna Wilkaniec, Marta Matuszewska, Ewelina Pałasz, Magdalena Cieślik, Agata Adamczyk
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 233 (2024)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/47fac4998ad34dc899677fe043cdf6bb
Autor:
Lidia Babiec, Anna Wilkaniec, Marta Matuszewska, Ewelina Pałasz, Magdalena Cieślik, Agata Adamczyk
Publikováno v:
Brain Sciences, Vol 13, Iss 7, p 1088 (2023)
Recent data suggest that defects in purinergic signalling are a common denominator of autism spectrum disorders (ASDs), though nothing is known about whether the disorder-related imbalance occurs at the receptor level. In this study, we investigated
Externí odkaz:
https://doaj.org/article/6dfce820fc0a4df4b900bbd19f52170d
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7243 (2023)
Maternal immune activation (MIA) is an important risk factor for neurodevelopmental disorders such as autism. The aim of the current study was to investigate the development-dependent changes in the mitochondrial function of MIA-exposed offspring, wh
Externí odkaz:
https://doaj.org/article/3b5db6f8d5d3410f805770a3f0be30fb
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6321 (2023)
Neurotrophic factors (NTFs) play an important role in maintaining homeostasis of the central nervous system (CNS) by regulating the survival, differentiation, maturation, and development of neurons and by participating in the regeneration of damaged
Externí odkaz:
https://doaj.org/article/21209df1e71044178c3a3c98fe2fe2c7
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 13 (2022)
The correct phagocytic activity of microglia is a prerequisite for maintaining homeostasis in the brain. In the analysis of mechanisms regulating microglial phagocytosis, we focused on the bromodomain and extraterminal domain (BET) proteins: Brd2, Br
Externí odkaz:
https://doaj.org/article/c0b7106a33e041e984afe2325924915f
Autor:
Anna Wilkaniec, Anna M. Lenkiewicz, Lidia Babiec, Emilia Murawska, Henryk M. Jęśko, Magdalena Cieślik, Carsten Culmsee, Agata Adamczyk
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Aberrant secretion and accumulation of α-synuclein (α-Syn) as well as the loss of parkin function are associated with the pathogenesis of Parkinson’s disease (PD). Our previous study suggested a functional interaction between those two proteins,
Externí odkaz:
https://doaj.org/article/7c827104395b46819f287f33340f635d
Autor:
Anna Wilkaniec, Magdalena Gąssowska-Dobrowolska, Marcin Strawski, Agata Adamczyk, Grzegorz A. Czapski
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-18 (2018)
Abstract Background Cyclin-dependent kinase 5 (Cdk5) belongs to the family of proline-directed serine/threonine kinases and plays a critical role in neuronal differentiation, migration, synaptogenesis, plasticity, neurotransmission and apoptosis. The
Externí odkaz:
https://doaj.org/article/ceab238d0c8240d09f3c8fd9287ca4d3