Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anna Vyborova"'
γ9δ2 T-Cell Expansion and Phenotypic Profile Are Reflected in the CDR3δ Repertoire of Healthy Adults
Autor:
Anna Vyborova, Anke Janssen, Lucrezia Gatti, Froso Karaiskaki, Austin Yonika, Sanne van Dooremalen, Jasper Sanders, Dennis X. Beringer, Trudy Straetemans, Zsolt Sebestyen, Jürgen Kuball
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
γ9δ2T cells fill a distinct niche in human immunity due to the unique physiology of the phosphoantigen-reactive γ9δ2TCR. Here, we highlight reproducible TCRδ complementarity-determining region 3 (CDR3δ) repertoire patterns associated with γ9δ
Externí odkaz:
https://doaj.org/article/dfb5fbd35a32484d8ceb964287caa82a
Autor:
Inez Johanna, Trudy Straetemans, Sabine Heijhuurs, Zsolt Sebestyen, Jürgen Kuball, Eline van Diest, Patricia Hernández López, Angelo D Meringa, Anna Vyborova, Froso Karaiskaki, Jan Gumathi Bormin, Sanne van Dooremalen, Mara J T Nicolasen, Lucrezia C D E Gatti, Dennis X Beringer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/de666a740e2143a1a08f52a3ccd29c36
Autor:
Anke Janssen, Eline van Diest, Anna Vyborova, Lenneke Schrier, Anke Bruns, Zsolt Sebestyen, Trudy Straetemans, Moniek de Witte, Jürgen Kuball
Publikováno v:
Viruses, Vol 14, Iss 1, p 117 (2022)
In the complex interplay between inflammation and graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (allo-HSCT), viral reactivations are often observed and cause substantial morbidity and mortality. As toxicity after allo-HS
Externí odkaz:
https://doaj.org/article/2322f1aa54704b9db02bce34b41fad08
Autor:
Zsolt Sebestyen, Wouter Scheper, Anna Vyborova, Siyi Gu, Zuzana Rychnavska, Marleen Schiffler, Astrid Cleven, Coraline Chéneau, Martje van Noorden, Cassie-Marie Peigné, Daniel Olive, Robert Jan Lebbink, Rimke Oostvogels, Tuna Mutis, Gerrit Jan Schuurhuis, Erin J. Adams, Emmanuel Scotet, Jürgen Kuball
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1973-1985 (2016)
Human Vγ9Vδ2 T cells respond to tumor cells by sensing elevated levels of phosphorylated intermediates of the dysregulated mevalonate pathway, which is translated into activating signals by the ubiquitously expressed butyrophilin A1 (BTN3A1) throug
Externí odkaz:
https://doaj.org/article/2db78a3619e04870be1de1e42066352c
Autor:
Maaike V. J. Braham, Monique C. Minnema, Tineke Aarts, Zsolt Sebestyen, Trudy Straetemans, Anna Vyborova, Jurgen Kuball, F. Cumhur Öner, Catherine Robin, Jacqueline Alblas
Publikováno v:
OncoImmunology, Vol 7, Iss 6 (2018)
Bone marrow niches support multiple myeloma, providing signals and cell-cell interactions essential for disease progression. A 3D bone marrow niche model was developed, in which supportive multipotent mesenchymal stromal cells and their osteogenic de
Externí odkaz:
https://doaj.org/article/d07485d338794a75bf4ea094870f2fa6
Autor:
Eline van Diest, Froso Karaiskaki, Dennis X. Beringer, Sanne van Dooremalen, Jürgen Kuball, Zsolt Sebestyén, Jan Gumathi Bormin, Lucrezia C D E Gatti, Trudy Straetemans, Inez Johanna, Anna Vyborova, Sabine Heijhuurs, Patricia Hernández López, Mara J T Nicolasen, Angelo D Meringa
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Backgroundγ9δ2 T cells hold great promise as cancer therapeutics because of their unique capability of reacting to metabolic changes with tumor cells. However, it has proven very difficult to translate this promise into clinical success.MethodsIn o
Autor:
Monique C. Minnema, Jacqueline Alblas, Catherine Robin, Jürgen Kuball, Tineke Aarts, Zsolt Sebestyén, Anna Vyborova, Maaike V.J. Braham, Trudy Straetemans, F. Cumhur Oner
Publikováno v:
Oncoimmunology
OncoImmunology, 7(6). Landes Bioscience
OncoImmunology, Vol 7, Iss 6 (2018)
OncoImmunology, 7(6). Landes Bioscience
OncoImmunology, Vol 7, Iss 6 (2018)
Bone marrow niches support multiple myeloma, providing signals and cell-cell interactions essential for disease progression. A 3D bone marrow niche model was developed, in which supportive multipotent mesenchymal stromal cells and their osteogenic de
Autor:
Sergei Tjulandin, Alexey Tryakin, Mikhail Fedyanin, Ilya Pokataev, Sergey Gordeev, Anna Vyborova, Vechaslav Aliev
Publikováno v:
Journal of Clinical Oncology. 32:e14643-e14643
e14643 Background: A role of maintenance chemotherapy (mCT) in patients (pts) with metastatic colorectal cancer (mCRC) is still controversial. The purpose of this retrospective study was to investi...