Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anna Vuorimaa"'
Autor:
Jussi Lehto, Marjo Nylund, Markus Matilainen, Marcus Sucksdorff, Anna Vuorimaa, Johan Rajander, Saara Wahlroos, Parisa Hariri, Laura Airas
Publikováno v:
European Journal of Neurology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bbbadc1c4d29e45a42d3373644c50cd
https://doi.org/10.1111/ene.15834
https://doi.org/10.1111/ene.15834
Autor:
Maija Saraste, Markus Matilainen, Anna Vuorimaa, Sini Laaksonen, Marcus Sucksdorff, David Leppert, Jens Kuhle, Laura Airas
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. :jnnp-2023
BackgroundTranslocator protein (TSPO)-PET and neurofilament light (NfL) both report on brain pathology, but their potential association has not yet been studied in multiple sclerosis (MS) in vivo. We aimed to evaluate the association between serum Nf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc849bef909fc0784a69951c7b84686
https://doi.org/10.1136/jnnp-2023-331051
https://doi.org/10.1136/jnnp-2023-331051
Autor:
Eero Polvinen, Eero Rissanen, Laura Airas, Marcus Sucksdorff, Jouni Tuisku, Markus Matilainen, Marjo Nylund, Anna Vuorimaa, Johanna Rokka
Publikováno v:
Brain
Sucksdorff et al. report that increased microglial and macrophage activation, as revealed by brain TSPO-PET, predicts multiple sclerosis progression independent of relapses during 4-year follow-up. Innate immune cell activation may thus contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a53bd328f46e9f79c7017788bf36ae
https://doi.org/10.1093/brain/awaa275
https://doi.org/10.1093/brain/awaa275
Autor:
Eero Rissanen, Laura Airas, Juha O. Rinne, Marcus Sucksdorff, Anna Vuorimaa, Sini Laaksonen, Svetlana Bezukladova, Virva Saunavaara, Mehrbod Mohammadian, Jouni Tuisku, Sarah Smith, Johanna Rokka, Markus Matilainen, Marjo Nylund
Objective To evaluate in vivo the co-occurrence of microglial activation and microstructural white matter damage in multiple sclerosis (MS) brain, and to examine their association with clinical disability. Methods 18-kDa translocator protein (TSPO) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbef9d97562647e7f543e4ae5b09331
Autor:
Markus Matilainen, Eero Rissanen, Laura Airas, Marjo Nylund, Anna Vuorimaa, Marcus Sucksdorff, Joonas Keitilä, Johanna Rokka, Juha O. Rinne, Sarah Smith, Riitta Parkkola, Jouni Tuisku
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
ObjectiveTo evaluate whether natalizumab treatment reduces microglial activation in MS.MethodsWe measured microglial activation using the 18-kDa translocator protein (TSPO)-binding radioligand [11C]PK11195 and PET imaging in 10 patients with MS befor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbad628f9a7496ad0c54f0af8028779
http://europepmc.org/articles/PMC6624093
http://europepmc.org/articles/PMC6624093
Autor:
Maija Saraste, Svetlana Bezukladova, Jens Kuhle, Sini Laaksonen, Jouni Tuisku, Eero Rissanen, Laura Airas, Markus Matilainen, David Leppert, Anna Vuorimaa, Marcus Sucksdorff
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveTo evaluate to which extent serum neurofilament light chain (NfL) increase is related to diffusion tensor imaging–MRI measurable diffuse normal-appearing white matter (NAWM) damage in MS.MethodsSeventy-nine patients with MS and 10 healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9245a7373879186113bb6df8562eaac9
https://doi.org/10.1212/nxi.0000000000000926
https://doi.org/10.1212/nxi.0000000000000926
Autor:
Eero Rissanen, Laura Airas, Mehrbod Mohammadian, Sini Laaksonen, Juha O. Rinne, Virva Saunavaara, Markus Matilainen, Svetlana Bezukladova, Marjo Nylund, Marcus Sucksdorff, Sarah Smith, Jouni Tuisku, Anna Vuorimaa, Johanna Rokka
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
ObjectiveTo evaluate in vivo the co-occurrence of microglial activation and microstructural white matter (WM) damage in the MS brain and to examine their association with clinical disability.Methods18-kDa translocator protein (TSPO) brain PET imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5465d364a19e836d1f5ff51a6861257
https://doi.org/10.1212/nxi.0000000000000691
https://doi.org/10.1212/nxi.0000000000000691
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 24(11)
Positron emission tomography (PET) gives an opportunity to quantitate the expression of specific molecular targets in vivo and longitudinally in brain and thus enhances our possibilities to understand and follow up multiple sclerosis (MS)-related pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83788da658170a83927c6a3310344fb
https://pubmed.ncbi.nlm.nih.gov/30091657
https://pubmed.ncbi.nlm.nih.gov/30091657
Publikováno v:
Contrast Media & Molecular Imaging
Contrast Media & Molecular Imaging, Vol 2017 (2017)
Contrast Media & Molecular Imaging, Vol 2017 (2017)
Adenosine receptors are G-protein coupled P1 purinergic receptors that are broadly expressed in the peripheral immune system, vasculature, and the central nervous system (CNS). Within the immune system, adenosine 2A (A2A) receptor-mediated signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4cf0e8b2a00f612a820bee3806421a
http://europepmc.org/articles/PMC5733838
http://europepmc.org/articles/PMC5733838