Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Anna Varizhuk"'
Autor:
Tatiana Vedekhina, Julia Svetlova, Iuliia Pavlova, Nikolay Barinov, Sabina Alieva, Elizaveta Malakhova, Pavel Rubtsov, Alina Shtork, Dmitry Klinov, Anna Varizhuk
Publikováno v:
Molecules, Vol 29, Iss 18, p 4369 (2024)
Abnormal intracellular phase transitions in mutant hnRNP A1 may underlie the development of several neurodegenerative diseases. The risk of these diseases increases upon C9Orf72 repeat expansion and the accumulation of the corresponding G-quadruplex
Externí odkaz:
https://doaj.org/article/b6d0d9acf0e74de0bafbd04a3d4c6600
Autor:
Ekaterina Knizhnik, Stepan Chumakov, Julia Svetlova, Iulia Pavlova, Yuri Khodarovich, Vladimir Brylev, Vjacheslav Severov, Rugiya Alieva, Liubov Kozlovskaya, Dmitry Andreev, Andrey Aralov, Anna Varizhuk
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1660 (2023)
Ribosomal frameshifting (RFS) at the slippery site of SARS-CoV-2 RNA is essential for the biosynthesis of the viral replication machinery. It requires the formation of a pseudoknot (PK) structure near the slippery site and can be inhibited by PK-disr
Externí odkaz:
https://doaj.org/article/5a4c58f2e2a34e5ea67bf152380c00dc
Autor:
Polina Kamzeeva, Nikolai Dagaev, Sofia Lizunova, Yuri Khodarovich, Anna Sogomonyan, Anastasia Kolchanova, Vadim Pokrovsky, Vera Alferova, Alexey Chistov, Artur Eshtukov-Shcheglov, Elizaveta Eshtukova-Shcheglova, Evgeny Belyaev, Dmitry Skvortsov, Anna Varizhuk, Andrey Aralov
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1669 (2023)
Azacarbazoles have attracted significant interest due to their valuable properties, such as anti-pathogenic and antitumor activity. In this study, a series of structurally related tricyclic benzo[4,5]- and tertacyclic naphtho[2′,1′:4,5]imidazo[1,
Externí odkaz:
https://doaj.org/article/2b0575bb2c3b480782aaab804d5581e3
Autor:
Egor Shitikov, Dmitry Bespiatykh, Maja Malakhova, Julia Bespyatykh, Ivan Bodoev, Tatiana Vedekhina, Marina Zaychikova, Vladimir Veselovsky, Ksenia Klimina, Elena Ilina, Anna Varizhuk
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
G-quadruplexes (G4s) are non-canonical DNA structures that could be considered as potential therapeutic targets for antimicrobial compounds, also known as G4-stabilizing ligands. While some of these ligands are shown in vitro to have a stabilizing ef
Externí odkaz:
https://doaj.org/article/e4933c1d8b044098a2f2162bc807b3d6
Autor:
Julia Galeeva, Vladislav Babenko, Ramiz Bakhtyev, Vladimir Baklaushev, Larisa Balykova, Pavel Bashkirov, Julia Bespyatykh, Anna Blagonravova, Daria Boldyreva, Dmitry Fedorov, Ilshat Gafurov, Raushaniya Gaifullina, Elena Galova, Alina Gospodaryk, Elena Ilina, Konstantin Ivanov, Daria Kharlampieva, Polina Khromova, Ksenia Klimina, Konstantin Kolontarev, Nadezhda Kolyshkina, Andrey Koritsky, Vyacheslav Kuropatkin, Vasily Lazarev, Alexander Manolov, Valentin Manuvera, Daria Matyushkina, Maxim Morozov, Ekaterina Moskaleva, Varvara Musarova, Oleg Ogarkov, Elizaveta Orlova, Alexander Pavlenko, Alla Petrova, Natalia Pozhenko, Dmitry Pushkar, Alexander Rumyantsev, Sergey Rumyantsev, Vladimir Rumyantsev, Lyubov Rychkova, Alexander Samoilov, Irina Shirokova, Vyacheslav Sinkov, Svetlana Solovieva, Elizaveta Starikova, Polina Tikhonova, Galina Trifonova, Alexander Troitsky, Alexander Tulichev, Yuri Udalov, Anna Varizhuk, Alexander Vasiliev, Vladimir Veselovsky, Rinat Vereshchagin, Alexey Volnukhin, Gaukhar Yusubalieva, Vadim Govorun
Publikováno v:
Data in Brief, Vol 40, Iss , Pp 107770- (2022)
The SARS-CoV-2 pandemic is a big challenge for humanity. The COVID-19 severity differs significantly from patient to patient, and it is important to study the factors protecting from severe forms of the disease. Respiratory microbiota may influence t
Externí odkaz:
https://doaj.org/article/06bdecddeb46401b82bef5f9bbb85aa4
Autor:
Daria Matyushkina, Varvara Shokina, Polina Tikhonova, Valentin Manuvera, Dmitry Shirokov, Daria Kharlampieva, Vasily Lazarev, Anna Varizhuk, Tatiana Vedekhina, Alexander Pavlenko, Leonid Penkin, Georgij Arapidi, Konstantin Pavlov, Dmitry Pushkar, Konstantin Kolontarev, Alexander Rumyantsev, Sergey Rumyantsev, Lyubov Rychkova, Vadim Govorun
Publikováno v:
Viruses, Vol 14, Iss 6, p 1141 (2022)
COVID-19 caused by SARS-CoV-2 is continuing to spread around the world and drastically affect our daily life. New strains appear, and the severity of the course of the disease itself seems to be decreasing, but even people who have been ill on an out
Externí odkaz:
https://doaj.org/article/0d507c2beb2d44429929e9a4d61371d6
Publikováno v:
Data in Brief, Vol 11, Iss C, Pp 258-265 (2017)
The data provided in this article are related to the research article "The expanding repertoire of G4 DNA structures" [1]. Secondary structures of G-rich oligonucleotides (ONs) that represent “imperfect” G-quadruplex (G4) motifs, i.e., contain tr
Externí odkaz:
https://doaj.org/article/8b263c4b53b74c9f9be5db601ee5f1cd
Autor:
Julia Bespyatykh, Dmitry Bespiatykh, Maja Malakhova, Ksenia Klimina, Andrey Bespyatykh, Anna Varizhuk, Anna Tevyashova, Tatiana Nikolenko, Galina Pozmogova, Elena Ilina, Egor Shitikov
Publikováno v:
Antibiotics, Vol 9, Iss 10, p 715 (2020)
Mycobacterium tuberculosis is one of the most dangerous pathogens. Bacterial resistance to antituberculosis drugs grows each year, but searching for new drugs is a long process. Testing for available drugs to find active against mycobacteria may be a
Externí odkaz:
https://doaj.org/article/bcbac0f8dad14f068a5853452365adff
Autor:
Yuliya Kirillova, Nataliya Boyarskaya, Andrey Dezhenkov, Mariya Tankevich, Ivan Prokhorov, Anna Varizhuk, Sergei Eremin, Dmitry Esipov, Igor Smirnov, Galina Pozmogova
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140468 (2015)
New polyanionic modifications of polyamide nucleic acid mimics were obtained. Thymine decamers were synthesized from respective chiral α- and γ-monomers, and their enantiomeric purity was assessed. Here, we present the decamer synthesis, purificati
Externí odkaz:
https://doaj.org/article/7f9c49b15ce64b0092e65c403ba1ba4e
Autor:
Olga Tatarinova, Vladimir Tsvetkov, Dmitry Basmanov, Nikolay Barinov, Igor Smirnov, Edward Timofeev, Dmitry Kaluzhny, Andrey Chuvilin, Dmitry Klinov, Anna Varizhuk, Galina Pozmogova
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89383 (2014)
Noncanonically structured DNA aptamers to thrombin were examined. Two different approaches were used to improve stability, binding affinity and biological activity of a known thrombin-binding aptamer. These approaches are chemical modification and th
Externí odkaz:
https://doaj.org/article/e2c11f32d6ed49ca8970cc49dc90411c