Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Anna Vainshtein"'
Autor:
Kae-Jiun Chang, Ira Agrawal, Anna Vainshtein, Wan Yun Ho, Wendy Xin, Greg Tucker-Kellogg, Keiichiro Susuki, Elior Peles, Shuo-Chien Ling, Jonah R Chan
Publikováno v:
eLife, Vol 10 (2021)
TDP-43 is extensively studied in neurons in physiological and pathological contexts. However, emerging evidence indicates that glial cells are also reliant on TDP-43 function. We demonstrate that deletion of TDP-43 in Schwann cells results in a drama
Externí odkaz:
https://doaj.org/article/806e78a46128409587bd9290f6d060f7
Autor:
Myriam Mirza, Anna Vainshtein, Alberto DiRonza, Uma Chandrachud, Luke J. Haslett, Michela Palmieri, Stephan Storch, Janos Groh, Niv Dobzinski, Gennaro Napolitano, Carolin Schmidtke, Danielle M. Kerkovich
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 12, Pp n/a-n/a (2019)
Abstract Background One of the most important steps taken by Beyond Batten Disease Foundation in our quest to cure juvenile Batten (CLN3) disease is to understand the State of the Science. We believe that a strong understanding of where we are in our
Externí odkaz:
https://doaj.org/article/ff6be28e0b18473a86341a67a5838308
Autor:
Nunzia Pastore, Anna Vainshtein, Tiemo J Klisch, Andrea Armani, Tuong Huynh, Niculin J Herz, Elena V Polishchuk, Marco Sandri, Andrea Ballabio
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 5, Pp 605-621 (2017)
Abstract TFE3 and TFEB are members of the MiT family of HLH–leucine zipper transcription factors. Recent studies demonstrated that they bind overlapping sets of promoters and are post‐transcriptionally regulated through a similar mechanism. Howev
Externí odkaz:
https://doaj.org/article/3577a82b5d6945a083275779521971e1
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The molecular mechanism controlling oligodendrocyte differentiation is not fully understood. Here the authors show that G protein coupled receptor 37 acts as a negative regulator of CNS myelination, and this effect is mediated by suppression of ERK s
Externí odkaz:
https://doaj.org/article/db5fa7523f93429b9dcb729dec275fe0
Autor:
Anna Vainshtein, Paolo Grumati
Publikováno v:
Cells, Vol 9, Iss 11, p 2349 (2020)
Autophagy, a bulk degradation process within eukaryotic cells, is responsible for cellular turnover and nutrient liberation during starvation. Increasing evidence indicate that this process can be extremely discerning. Selective autophagy segregates
Externí odkaz:
https://doaj.org/article/9cfe4034908c4bc19a33efc903fccb1c
Autor:
Anna Vainshtein, Marco Sandri
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4759 (2020)
The loss of skeletal muscle mass under a wide range of acute and chronic maladies is associated with poor prognosis, reduced quality of life, and increased mortality. Decades of research indicate the importance of skeletal muscle for whole body metab
Externí odkaz:
https://doaj.org/article/73a244c7a4bc466cbf0bfe263ba6dbe5
Publikováno v:
eLife, Vol 6 (2017)
Treatment for medulloblastoma, the most common malignant brain tumor in children, remains limited to surgical resection, radiation, and traditional chemotherapy; with long-term survival as low as 50–60% for Sonic Hedgehog (Shh)-type medulloblastoma
Externí odkaz:
https://doaj.org/article/fd0a1dca13fe469f801db1478840a3ea
Publikováno v:
Integrative Medicine Research, Vol 3, Iss 4, Pp 161-171 (2014)
Chronic muscle disuse, such as that resulting from immobilization, denervation, or prolonged physical inactivity, produces atrophy and a loss of mitochondria, yet the molecular relationship between these events is not fully understood. In this review
Externí odkaz:
https://doaj.org/article/96d7b7724937460baaa1a6b330feb712
Autor:
Veronique Amor, Chuansheng Zhang, Anna Vainshtein, Ao Zhang, Daniel R Zollinger, Yael Eshed-Eisenbach, Peter J Brophy, Matthew N Rasband, Elior Peles
Publikováno v:
eLife, Vol 6 (2017)
A high density of Na+ channels at nodes of Ranvier is necessary for rapid and efficient action potential propagation in myelinated axons. Na+ channel clustering is thought to depend on two axonal cell adhesion molecules that mediate interactions betw
Externí odkaz:
https://doaj.org/article/d413c2b8c31449edb49d2a41b7f1a9d2
Autor:
Anna Vainshtein, Mikhaela B. Slavin, Arthur J. Cheng, Jonathan M. Memme, Ashley N. Oliveira, Christopher G. R. Perry, Ali A. Abdul-Sater, Angelo N. Belcastro, Michael C. Riddell, Matthew Triolo, Tara L. Haas, Emilie Roudier, David A. Hood
Publikováno v:
Journal of Applied Physiology. 133:1381-1393
Exercise is one of the only non-pharmacologic remedies known to counteract genetic and chronic diseases by enhancing health and improving life span. Although the many benefits of regular physical activity have been recognized for some time, the intri