Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anna V. Kotrys"'
Publikováno v:
Nature Biotechnology. 40:1378-1387
The all-protein cytosine base editor DdCBE uses TALE proteins and a double-stranded DNA-specific cytidine deaminase (DddA) to mediate targeted C•G-to-T•A editing. To improve editing efficiency and overcome the strict TC sequence-context constrain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d408779dbce201fe37bf5e963c45ca
https://doi.org/10.1038/s41587-022-01256-8
https://doi.org/10.1038/s41587-022-01256-8
Autor:
Roman J Szczesny, Katarzyna Kowalska, Kamila Klosowska-Kosicka, Aleksander Chlebowski, Ewelina P Owczarek, Zbigniew Warkocki, Tomasz M Kulinski, Dorota Adamska, Kamila Affek, Agata Jedroszkowiak, Anna V Kotrys, Rafal Tomecki, Pawel S Krawczyk, Lukasz S Borowski, Andrzej Dziembowski
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194887 (2018)
Deciphering a function of a given protein requires investigating various biological aspects. Usually, the protein of interest is expressed with a fusion tag that aids or allows subsequent analyses. Additionally, downregulation or inactivation of the
Externí odkaz:
https://doaj.org/article/5a180779111c48eab736888d65918961
Autor:
Tslil Ast, Shayan Sadre, Pallavi R. Joshi, Owen S. Skinner, Anna V. Kotrys, Melissa A. Walker, Tsz-Leung To, Zenon Grabarek, Hong Wang, Maria Miranda, Wendy H. W. Hung, Joshua D. Meisel, Mary E. Haas, Alexis A. Jourdain, Sneha Rath, Connie Chan, Sharon H. Kim, Chen-Ching Yuan, Hardik Shah, Patrick S. Ward, Timothy J. Durham, Robert S. Rogers, Anupam Patgiri, Rohit Sharma, Russell P. Goodman, Stephanie S Lam, Rahul Gupta, Jason G. McCoy, Sarah E. Calvo, Apekshya Panda, Vamsi K. Mootha, Jordan Wengrod
Publikováno v:
Nucleic Acids Research, vol. 49, no. D1, pp. D1541-D1547
Nucleic Acids Research
Nucleic Acids Research
The mammalian mitochondrial proteome is under dual genomic control, with 99% of proteins encoded by the nuclear genome and 13 originating from the mitochondrial DNA (mtDNA). We previously developed MitoCarta, a catalogue of over 1000 genes encoding t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63c9eff157958e650b999555c9273cf
https://doi.org/10.1093/nar/gkaa1011
https://doi.org/10.1093/nar/gkaa1011
Autor:
Beverly Y, Mok, Anna V, Kotrys, Aditya, Raguram, Tony P, Huang, Vamsi K, Mootha, David R, Liu
Publikováno v:
Nature biotechnology. 40(9)
The all-protein cytosine base editor DdCBE uses TALE proteins and a double-stranded DNA-specific cytidine deaminase (DddA) to mediate targeted C•G-to-T•A editing. To improve editing efficiency and overcome the strict TC sequence-context constrain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a33137aca8ffe34eb2b912834c26c56
https://pubmed.ncbi.nlm.nih.gov/35379961
https://pubmed.ncbi.nlm.nih.gov/35379961
Autor:
Sylwia D. Czarnomska, Lukasz S. Borowski, Andrzej Dziembowski, Dominik Cysewski, Anna V. Kotrys, Roman J. Szczesny, Zbigniew Pietras
Publikováno v:
Nucleic Acids Research
Maintenance of mitochondrial gene expression is crucial for cellular homeostasis. Stress conditions may lead to a temporary reduction of mitochondrial genome copy number, raising the risk of insufficient expression of mitochondrial encoded genes. Lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ace476abebe12858946df0a70c9df6
https://doi.org/10.1093/nar/gkz542
https://doi.org/10.1093/nar/gkz542
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2192
RNA turnover is an essential part of the gene expression pathway, and there are several experimental approaches for its determination. High-throughput measurement of global RNA turnover rates can provide valuable information about conditions or prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84a986de2faa42ea2c7dcd85f51a7215
https://pubmed.ncbi.nlm.nih.gov/33230771
https://pubmed.ncbi.nlm.nih.gov/33230771
Publikováno v:
Methods in Molecular Biology ISBN: 9781071608333
RNA turnover is an essential part of the gene expression pathway, and there are several experimental approaches for its determination. High-throughput measurement of global RNA turnover rates can provide valuable information about conditions or prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a26a335c0d4b5bde5e73411b0b2256fe
https://doi.org/10.1007/978-1-0716-0834-0_11
https://doi.org/10.1007/978-1-0716-0834-0_11
Autor:
Anna V. Kotrys, Sylwia D. Czarnomska, Deepshikha Malik, Roman J. Szczesny, Marcin Nowotny, Maciej Szewczyk, Kamila Klosowska-Kosicka, Lukasz S. Borowski
Publikováno v:
Nucleic acids research 48(10), 5572-5590 (2020). doi:10.1093/nar/gkaa302
Nucleic Acids Research
Nucleic Acids Research
Nucleic acids research / Special publication 48(10), 5572 - 5590 (2020). doi:10.1093/nar/gkaa302
RNA decay is a key element of mitochondrial RNA metabolism. To date, the only well-documented machinery that plays a role in mtRNA decay in humans i
RNA decay is a key element of mitochondrial RNA metabolism. To date, the only well-documented machinery that plays a role in mtRNA decay in humans i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fff9843dd92ea2c33044313c3429e86
https://bib-pubdb1.desy.de/record/442751
https://bib-pubdb1.desy.de/record/442751
Autor:
Roman J. Szczesny, Anna V. Kotrys
Publikováno v:
Cells
Mitochondria are peculiar organelles whose proper function depends on the crosstalk between two genomes, mitochondrial and nuclear. The human mitochondrial genome (mtDNA) encodes only 13 proteins; nevertheless, its proper expression is essential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12037ee31612c98b3fda7686469ce5e0
http://europepmc.org/articles/PMC7017415
http://europepmc.org/articles/PMC7017415
Autor:
Mohammed Imran Khan, Anna V. Kotrys, Paweł Krasowski, Anna Kornakiewicz, Cezary Szczylik, Anna M. Czarnecka
Publikováno v:
Stem cell reviews and reports. 14(3)
The aim of this study was to compare effect of everolimus on growth of different renal cell carcinoma (RCC) populations and develop experimental design to measure the early response of everolimus in clear cell RCC (ccRCC) cell lines including renal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2992d309cbdb20ae33d078b777e4f4
https://pubmed.ncbi.nlm.nih.gov/29508215
https://pubmed.ncbi.nlm.nih.gov/29508215