Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anna V. Epanchintseva"'
Autor:
Anna V. Epanchintseva, Julia E. Poletaeva, Irina A. Bakhno, Vladimir V. Belov, Alina E. Grigor’eva, Svetlana V. Baranova, Elena I. Ryabchikova, Ilya S. Dovydenko
Publikováno v:
Nanomaterials, Vol 13, Iss 24, p 3094 (2023)
Spontaneous sorption of proteins on the nanoparticles’ surface leads to the fact that nanoparticles in biological media are always enveloped by a layer of proteins—the protein corona. Corona proteins affect the properties of nanoparticles and the
Externí odkaz:
https://doaj.org/article/df5888643f5f4238a5d216d9496b728e
Publikováno v:
Applied Sciences, Vol 13, Iss 12, p 7324 (2023)
Understanding the patterns of noncovalent adsorption of double-stranded nucleic acids (dsDNA) on gold nanoparticles (GNPs) was the aim of this study. It was found that the high-affinity motifs in DNA can and do act as an “anchor” for the fixation
Externí odkaz:
https://doaj.org/article/660ee7b1d3094f2bac7a2fdc59f5bbd9
Autor:
Anna V. Epanchintseva, Julia E. Poletaeva, Dmitrii V. Pyshnyi, Elena I. Ryabchikova, Inna A. Pyshnaya
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 2568-2578 (2019)
Gold nanoparticles (AuNPs) are a platform for the creation of nanoconstructions that can have a variety of functions, including the delivery of therapeutic nucleic acids. We previously designed a AuNP/small interfering RNA (siRNA) nanoconstruction co
Externí odkaz:
https://doaj.org/article/1890ed82c488452480fa6a658598a978
Autor:
Anna V. Epanchintseva, Julia E. Poletaeva, Anton S. Dome, Ilya S. Dovydenko, Inna A. Pyshnaya, Elena I. Ryabchikova
Publikováno v:
Nanomaterials, Vol 12, Iss 24, p 4450 (2022)
Small interfering RNAs (siRNAs) are a powerful tool for specific suppression of protein synthesis in the cell, and this determines the attractiveness of siRNAs as a drug. Low resistance of siRNA to nucleases and inability to enter into target cells a
Externí odkaz:
https://doaj.org/article/1806a074a2184afbb569906a88d07243
Autor:
Anna V. Epanchintseva, Julia E. Poletaeva, Ilya S. Dovydenko, Boris P. Chelobanov, Dmitrii V. Pyshnyi, Elena I. Ryabchikova, Inna A. Pyshnaya
Publikováno v:
Nanomaterials, Vol 11, Iss 11, p 2775 (2021)
There is an urgent need to develop systems for nucleic acid delivery, especially for the creation of effective therapeutics against various diseases. We have previously shown the feasibility of efficient delivery of small interfering RNA by means of
Externí odkaz:
https://doaj.org/article/f0e5ea8054c849ac95ad2f10fdc5d8b2
Autor:
Anna V. Epanchintseva, Ekaterina A. Gorbunova, Elena I. Ryabchikova, Inna A. Pyshnaya, Dmitrii V. Pyshnyi
Publikováno v:
Nanomaterials, Vol 11, Iss 5, p 1178 (2021)
Fluorophore (FD) labeling is widely used for detection and quantification of various compounds bound to nanocarriers. The systems, composed of gold nanoparticles (GNPs) and oligonucleotides (ONs) labeled with FDs, have wide applications. Our work was
Externí odkaz:
https://doaj.org/article/3ae559a9d1544f018ede0dac51ada5ff
Publikováno v:
Applied Sciences; Volume 13; Issue 12; Pages: 7324
Understanding the patterns of noncovalent adsorption of double-stranded nucleic acids (dsDNA) on gold nanoparticles (GNPs) was the aim of this study. It was found that the high-affinity motifs in DNA can and do act as an “anchor” for the fixation
Autor:
Dmitrii V. Pyshnyi, Inna A. Pyshnaya, Boris P. Chelobanov, Julia Poletaeva, Anna V. Epanchintseva, Elena I. Ryabchikova, Ilya S. Dovydenko
Publikováno v:
Nanomaterials, Vol 11, Iss 2775, p 2775 (2021)
Nanomaterials
Volume 11
Issue 11
Nanomaterials
Volume 11
Issue 11
There is an urgent need to develop systems for nucleic acid delivery, especially for the creation of effective therapeutics against various diseases. We have previously shown the feasibility of efficient delivery of small interfering RNA by means of
Autor:
Dmitrii V. Pyshnyi, P. E. Vorobjev, V. V. Shashkova, Kristina V. Razum, Anna V. Epanchintseva, Elena I. Ryabchikova, Inna A. Pyshnaya
Publikováno v:
Russian Journal of Bioorganic Chemistry. 43:64-70
The development of nanodevices for the efficient transport of therapeutic molecules is one of the most urgent problems of modern molecular medicine. Noncovalent agents for the delivery of nucleic acids (NA) including those based on gold nanoparticles
Autor:
Anna V. Epanchintseva, Marsel R. Kabilov, P. E. Vorobjev, Inna A. Pyshnaya, Aleksey E. Tupikin, Dmitrii V. Pyshnyi, Alexander A. Lomzov
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 35(24)
Native DNA strongly adsorbs to citrate-coated gold nanoparticles (AuNPs). The resulting composites (DNA/AuNPs) are valuable materials in many fields, especially in biomedicine. For this reason, the process of adsorption is a focus for intensive resea