Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Anna V Yudkina"'
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198480 (2018)
DNA-protein cross-links (DPCs) are important DNA lesions induced by endogenous crosslinking agents such as formaldehyde or acetaldehyde, as well as ionizing radiation, cancer chemotherapeutic drugs, and abortive action of some enzymes. Due to their v
Externí odkaz:
https://doaj.org/article/46ee9d7b8eb94a3da0403d9222c0e73a
Autor:
Anton V. Endutkin, Anna V. Yudkina, Timofey D. Zharkov, Alexander E. Barmatov, Daria V. Petrova, Daria V. Kim, Dmitry O. Zharkov
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 681 (2024)
Clickable nucleosides, most often 5-ethynyl-2′-deoxyuridine (EtU), are widely used in studies of DNA replication in living cells and in DNA functionalization for bionanotechology applications. Although clickable dNTPs are easily incorporated by DNA
Externí odkaz:
https://doaj.org/article/ced9c58d729146a7ba9d26c0baf44698
Autor:
Elizaveta O. Boldinova, Anna V. Yudkina, Evgeniy S. Shilkin, Diana I. Gagarinskaya, Andrey G. Baranovskiy, Tahir H. Tahirov, Dmitry O. Zharkov, Alena V. Makarova
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Human PrimPol belongs to the archaeo-eukaryotic primase superfamily of primases and is involved in de novo DNA synthesis downstream of blocking DNA lesions and non-B DNA structures. PrimPol possesses both DNA/RNA primase and DNA polymerase a
Externí odkaz:
https://doaj.org/article/4385708681084e81aa35235773846c76
Autor:
Inga R. Grin, Grigory V. Mechetin, Rustem D. Kasymov, Evgeniia A. Diatlova, Anna V. Yudkina, Sergei N. Shchelkunov, Irina P. Gileva, Alexandra A. Denisova, Grigoriy A. Stepanov, Ghermes G. Chilov, Dmitry O. Zharkov
Publikováno v:
Molecules, Vol 26, Iss 21, p 6668 (2021)
Uracil–DNA glycosylases are enzymes that excise uracil bases appearing in DNA as a result of cytosine deamination or accidental dUMP incorporation from the dUTP pool. The activity of Family 1 uracil–DNA glycosylase (UNG) activity limits the effic
Externí odkaz:
https://doaj.org/article/4eccb9b2add64a62a6373d3ddfe88e90
Autor:
Zharkov, Anna V. Yudkina, Alexander E. Barmatov, Nikita A. Bulgakov, Elizaveta O. Boldinova, Evgeniy S. Shilkin, Alena V. Makarova, Dmitry O.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10877
DNA–protein cross-links remain the least-studied type of DNA damage. Recently, their repair was shown to involve proteolysis; however, the fate of the peptide remnant attached to DNA is unclear. Particularly, peptide cross-links could interfere wit
Autor:
Anna V Yudkina, Nikita A Bulgakov, Daria V Kim, Svetlana V Baranova, Alexander A Ishchenko, Murat K Saparbaev, Vladimir V Koval, Dmitry O Zharkov
Publikováno v:
Nucleic Acids Research.
Apurinic/apyrimidinic (AP) sites are abundant DNA lesions arising from spontaneous hydrolysis of the N-glycosidic bond and as base excision repair (BER) intermediates. AP sites and their derivatives readily trap DNA-bound proteins, resulting in DNA
Publikováno v:
Crystals, Vol 9, Iss 5, p 269 (2019)
7,8-Dihydro-8-oxoguanine (oxoG) is the most abundant oxidative DNA lesion with dual coding properties. It forms both Watson−Crick (anti)oxoG:(anti)C and Hoogsteen (syn)oxoG:(anti)A base pairs without a significant distortion of a B-DNA helix. DNA p
Externí odkaz:
https://doaj.org/article/9356438cb2e4463185ac4611b6251330
Autor:
Evgeniia A. Diatlova, Grigory V. Mechetin, Anna V. Yudkina, Vasily D. Zharkov, Natalia A. Torgasheva, Anton V. Endutkin, Olga V. Shulenina, Andrey L. Konevega, Irina P. Gileva, Sergei N. Shchelkunov, Dmitry O. Zharkov
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9113
The protein encoded by the vaccinia virus D4R gene has base excision repair uracil–DNA N-glycosylase (vvUNG) activity and also acts as a processivity factor in the viral replication complex. The use of a protein unlike PolN/PCNA sliding clamps is a
Autor:
M. A. Dymova, Dmitry O. Zharkov, E. A. Khrapov, V V Polunovsky, G V Mechetin, N A Torgasheva, A. I. Zakabunin, A V Endutkin, Maksim L. Filipenko, Anna V. Yudkina
Publikováno v:
Молекулярная биология. 55:258-268
Mycobacterium tuberculosis cells contain two apurinic/apyrimidinic (AP) endonucleases, endonuclease IV (MtbEnd) and exonuclease III (MtbXthA), the former playing a dominant role in protecting mycobacterial DNA from oxidative stress. Mycobacterial end
Autor:
Natalia A. Torgasheva, Evgeniia A. Diatlova, Inga R. Grin, Anton V. Endutkin, Grigory V. Mechetin, Ivan P. Vokhtantsev, Anna V. Yudkina, Dmitry O. Zharkov
Publikováno v:
International journal of molecular sciences. 23(13)
Many proteins consist of two or more structural domains: separate parts that have a defined structure and function. For example, in enzymes, the catalytic activity is often localized in a core fragment, while other domains or disordered parts of the