Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anna V Roschke"'
Autor:
Ester Rozenblum, Jose R Sotelo-Silveira, Gina Y Kim, Jack Y Zhu, Christopher C Lau, Nicole McNeil, Susana Korolevich, Hongling Liao, James M Cherry, David J Munroe, Thomas Ried, Paul S Meltzer, Walter M Kuehl, Anna V Roschke
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182610 (2017)
A new ovarian near-diploid cell line, OVDM1, was derived from a highly aneuploid serous ovarian metastatic adenocarcinoma. A metastatic tumor was obtained from a 47-year-old Ashkenazi Jewish patient three years after the first surgery removed the pri
Externí odkaz:
https://doaj.org/article/dba79d739dea4b88b3e99d1b86610c4c
Autor:
Anna V Roschke, Ester eRozenblum
Publikováno v:
Frontiers in Oncology, Vol 3 (2013)
Whole chromosomal instability (W-CIN) – unequal chromosome distribution during cell division - is a characteristic feature of a majority of cancer cells distinguishing them from their normal counterparts. The precise molecular mechanisms that may c
Externí odkaz:
https://doaj.org/article/ad09543593a146a4b80a835d1c869e27
Autor:
Ilan R. Kirsch, Kristen S. Gelhaus, Anna V. Roschke, David G. Covell, Ruili Huang, Anders Wallqvist
The karyotypic features of cancer cells have not been a particular focus of anticancer drug targeting either as guidance for treatment or as specific drug targets themselves. Cancer cell lines typically have considerable, characteristic, and variable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c08ce440fdf11ae49179cab924c170d
https://doi.org/10.1158/1535-7163.c.6531978.v1
https://doi.org/10.1158/1535-7163.c.6531978.v1
Autor:
Ilan R. Kirsch, Kristen S. Gelhaus, Anna V. Roschke, David G. Covell, Ruili Huang, Anders Wallqvist
Supplementary Tables A-M from Drugs aimed at targeting characteristic karyotypic phenotypes of cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cd08cdd5b45d8c2895569500fe4538
https://doi.org/10.1158/1535-7163.22485531
https://doi.org/10.1158/1535-7163.22485531
Autor:
Anna V. Roschke, Oleg K. Glebov, Samir Lababidi, Kristen S. Gehlhaus, John N. Weinstein, Ilan R. Kirsch
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 11, Pp 1222-1230 (2008)
Chromosomal instability—a hallmark of epithelial cancers—is an ongoing process that results in aneuploidy and karyotypic heterogeneity of a cancer cell population. Previously, we stratified cancer cell lines in the NCI-60 drug discovery panel bas
Externí odkaz:
https://doaj.org/article/704a83da020d4d53be9d5910974efe7c
Autor:
W. M. Kuehl, Yan W. Asmann, Anna V. Roschke, Peter Leif Bergsagel, Yulia N. Demchenko, Wei Dong Chen
Publikováno v:
Nucleic Acids Research
Using a combination of array comparative genomic hybridization, mate pair and cloned sequences, and FISH analyses, we have identified in multiple myeloma cell lines and tumors a novel and recurrent type of genomic rearrangement, i.e. interchromosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf1aac0577069393536bbb5f7a2a3bf
https://doi.org/10.1093/nar/gkw527
https://doi.org/10.1093/nar/gkw527
Publikováno v:
Scientific Reports
Gross chromosomal rearrangements (GCRs), including translocations, inversions amplifications, and deletions, can be causal events leading to malignant transformation. GCRs are thought to be triggered by DNA double strand breaks (DSBs), which in turn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c17291fa1072b2a428c01a2cfc0ccd
Autor:
Ana Gabrea, Gina Y. Kim, W. Michael Kuehl, Yulia N. Demchenko, Leif Bergsagel, Anna V. Roschke
Publikováno v:
Genes, Chromosomes and Cancer. 53:467-474
Primary IGH translocations involving seven recurrent partner loci and oncogenes are present in about 40% of multiple myeloma tumors. Secondary IGH rearrangements, which occur in a smaller fraction of tumors, usually are complex structures, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55101af67b4ff1a625e9937ca9ccab68
https://doi.org/10.1002/gcc.22158
https://doi.org/10.1002/gcc.22158
Autor:
Paul S. Meltzer, Anna V. Roschke, Ilan R. Kirsch, Robert L. Walker, Yoonsoo Park, Ester Rozenblum, Geula Klorin, Frederic J. Kaye, Oleg K. Glebov
Publikováno v:
Cancer Genetics. 206:191-205
High-resolution oligonucleotide array comparative genomic hybridization (aCGH) and spectral karyotyping (SKY) were applied to a panel of malignant mesothelioma (MMt) cell lines. SKY has not been applied to MMt before, and complete karyotypes are repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e85a51cc6c8726496a2adbe4634089
https://doi.org/10.1016/j.cancergen.2013.04.006
https://doi.org/10.1016/j.cancergen.2013.04.006
Autor:
Samir Lababidi, John N. Weinstein, Kristen Gehlhaus, Oleg K. Glebov, Anna V. Roschke, Ilan R. Kirsch
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 11, Pp 1222-1230 (2008)
Chromosomal instability—a hallmark of epithelial cancers—is an ongoing process that results in aneuploidy and karyotypic heterogeneity of a cancer cell population. Previously, we stratified cancer cell lines in the NCI-60 drug discovery panel bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2571e283323bac4b1af710c5aff642b
http://www.sciencedirect.com/science/article/pii/S147655860880019X
http://www.sciencedirect.com/science/article/pii/S147655860880019X