Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anna Umano"'
Autor:
Ran Ming, Jamie B. Scaglione, Adam J. Kanack, Erik Soderblom, Anna Umano, Kanesha L. Travis, Yumei Wu, Oliver J. Newsom, Matthew G. Thompson, K. Matthew Scaglione
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaf3c4e9c3d47705843131dc20775474
https://doi.org/10.2139/ssrn.4254227
https://doi.org/10.2139/ssrn.4254227
Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation
Autor:
Dan Li, Sagar Lonial, Lina Song, Sumin Kang, Kelly R. Magliocca, Anna Umano, Zhuo Georgia Chen, Dong M. Shin, Jaemoo Chun, Austin C. Boese, Jie Li, Nabil F. Saba, JiHoon Kang, Taofeek K. Owonikoko, Chaoyun Pan, Lingtao Jin, Yunhan Jiang
Publikováno v:
Journal of Clinical Investigation. 129:4110-4123
Microtubule-associated serine/threonine kinase 1 (MAST1) is a central driver of cisplatin resistance in human cancers. However, the molecular mechanism regulating MAST1 levels in cisplatin-resistant tumors is unknown. Through a proteomics screen, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8121302ec1fbe0d148347555a76a2171
https://doi.org/10.1172/jci125963
https://doi.org/10.1172/jci125963
Autor:
Chaoyun Pan, JiHoon Kang, Yu Zhang, Anna Umano, Wenqing Yang, Sumin Kang, Lingtao Jin, Kelly R. Magliocca, Austin C. Boese, Sagar Lonial, Jie Li
Publikováno v:
Clin Cancer Res
Purpose: Although platinum compounds are the first-line treatment for ovarian cancer, the majority of patients relapse and develop resistance to treatment. However, the mechanism underlying resistance is unclear. The goal of our study is to decipher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3703855e64145398e035f5c3c6e3dcbf
https://pubmed.ncbi.nlm.nih.gov/32341033
https://pubmed.ncbi.nlm.nih.gov/32341033
Publikováno v:
Cancer Research. 80:4084-4084
Although platinum compounds are the first-line treatment for ovarian cancer, the majority of patients relapse and develop resistance to treatment. However, the mechanism underlying resistance is unclear. Here, we report a unique platinum resistance m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce36de73c4720c33566aae37eb64ec2d
https://doi.org/10.1158/1538-7445.am2020-4084
https://doi.org/10.1158/1538-7445.am2020-4084