Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anna Tramarin"'
Autor:
Annachiara Gandini, Ana Elisa Gonçalves, Silvia Strocchi, Claudia Albertini, Jana Janočková, Anna Tramarin, Daniela Grifoni, Eleonora Poeta, Ondrej Soukup, Diego Muñoz-Torrero, Barbara Monti, Raimon Sabaté, Manuela Bartolini, Giuseppe Legname, Maria Laura Bolognesi
Publikováno v:
ACS Chemical Neuroscience. 13:3314-3329
Alzheimer's disease (AD), the most common type of dementia, currently represents an extremely challenging and unmet medical need worldwide. Amyloid-β (Aβ) and Tau proteins are prototypical AD hallmarks, as well as validated drug targets. Accumulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120f6def0a91bcbe6be2b2a3c0aece78
https://doi.org/10.1021/acschemneuro.2c00357
https://doi.org/10.1021/acschemneuro.2c00357
Autor:
Annachiara, Gandini, Ana Elisa, Gonçalves, Silvia, Strocchi, Claudia, Albertini, Jana, Janočková, Anna, Tramarin, Daniela, Grifoni, Eleonora, Poeta, Ondrej, Soukup, Diego, Muñoz-Torrero, Barbara, Monti, Raimon, Sabaté, Manuela, Bartolini, Giuseppe, Legname, Maria Laura, Bolognesi
Publikováno v:
ACS chemical neuroscience. 13(23)
Alzheimer's disease (AD), the most common type of dementia, currently represents an extremely challenging and unmet medical need worldwide. Amyloid-β (Aβ) and Tau proteins are prototypical AD hallmarks, as well as validated drug targets. Accumulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17b5e484608a73b334805b090666dc05
https://pubmed.ncbi.nlm.nih.gov/36445009
https://pubmed.ncbi.nlm.nih.gov/36445009
Autor:
Elisa Uliassi, Flaminia Di Pietri, Ondrej Soukup, Manuela Bartolini, Claudia Albertini, Anna Tramarin, Lenka Pulkrabkova, Maria Laura Bolognesi, Sabrina Petralla, Rosaria Carmela Perone, Nicola Rizzardi, Romana Fato, Pedro de Sena Murteira Pinheiro
Publikováno v:
ChemMedChem. 16:187-198
Thanks to the widespread use and safety profile of donepezil (1) in the treatment of Alzheimer's disease (AD), one of the most widely adopted multi-target-directed ligand (MTDL) design strategies is to modify its molecular structure by linking a seco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1485fc5d25dca0b7c46d0c7398c7b08
https://doi.org/10.1002/cmdc.202000484
https://doi.org/10.1002/cmdc.202000484
Autor:
Giulio Vistoli, Marina Naldi, Loredana Lupu, Genny Degani, Anna Tramarin, Angelica Mazzolari, Michael Przybylski, Pascal Wiegand, Giancarlo Aldini, Alessandra Altomare, Manuela Bartolini, Laura Popolo
Publikováno v:
Analytical and Bioanalytical Chemistry. 412:4245-4259
Serum levels of early-glycated albumin are significantly increased in patients with diabetes mellitus and may play a role in worsening inflammatory status and sustaining diabetes-related complications. To investigate possible pathological recognition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b5107f2417e7fc4686e19a6cc245ee
https://doi.org/10.1007/s00216-020-02674-w
https://doi.org/10.1007/s00216-020-02674-w
Autor:
Marina Naldi, Daniele Tedesco, Maurizio Baldassarre, Manuela Bartolini, Anna Tramarin, Carlo Bertucci
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 162:171-178
The ADMET profile of drugs is strongly affected by human serum albumin (HSA), due to its leading role as carrier of poorly soluble compounds in plasma; a critical assessment of the binding capacity of HSA and the evaluation of binding competition bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9704308fa05013a0d6785aa8684095
https://doi.org/10.1016/j.jpba.2018.09.022
https://doi.org/10.1016/j.jpba.2018.09.022
Autor:
Anna Tramarin, Marina Naldi, Loredana Lupu, Pascal Wiegand, Edoardo Fabini, Genny Degani, Laura Popolo, Giancarlo Aldini, Michael Przybylski, Manuela Bartolini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::f253409ed0deb9fdc5c17538beb23071
http://hdl.handle.net/11585/664882
http://hdl.handle.net/11585/664882
Autor:
Salwa Elkazaz, Ehab D. AlFadly, Ignacio Moraleda, Manuela Bartolini, Marwa M. Abu-Serie, Hossam A. Shaltout, Ahmed S.F. Belal, Firas Kobeissy, Manal N. S. Saudi, Nour-Mounira Z. Bakkar, Anna Tramarin, Perihan A. Elzahhar, Ondrej Soukup, Isabel Iriepa, Jana Janockova, Rim W. Rafeh, Doaa A. Ghareeb, Ahmed F. El-Yazbi
Neuroinflammation and cholinergic deficit are key detrimental processes involved in Alzheimer's disease. Hence, in the search for novel and effective treatment strategies, the multi-target-directed ligand paradigm was applied to the rational design o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031881920a4c00a64ef8ef14bb5dee2e
http://hdl.handle.net/11585/726234
http://hdl.handle.net/11585/726234