Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anna Tikka"'
Autor:
Ilenia Minicocci, Anna Tikka, Eleonora Poggiogalle, Jari Metso, Anna Montali, Fabrizio Ceci, Giancarlo Labbadia, Mario Fontana, Alessia Di Costanzo, Marianna Maranghi, Aldo Rosano, Christian Ehnholm, Lorenzo Maria Donini, Matti Jauhiainen, Marcello Arca
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 6, Pp 1097-1107 (2016)
The consequences of angiopoietin-like protein 3 (ANGPTL3) deficiency on postprandial lipid and lipoprotein metabolism has not been investigated in humans. We studied 7 homozygous (undetectable circulating ANGPTL3 levels) and 31 heterozygous (50% of c
Externí odkaz:
https://doaj.org/article/e3b959eb3eb143e98fb585b680745bdf
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 77:601-609
Genetic variants of angiopoietin-like protein 3 (ANGPTL3) are associated with serum triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) concentration in GWASs. ANGPTL3 deficiency causes declined TG, total cholesterol (TC), LDL-C, high-d
Autor:
Anna Tikka, Alessia Di Costanzo, Fabrizio Ceci, Aldo Rosano, Lorenzo M. Donini, Eleonora Poggiogalle, Jari Metso, Giancarlo Labbadia, Christian Ehnholm, Anna Montali, Mario Fontana, Marianna Maranghi, Matti Jauhiainen, Marcello Arca, Ilenia Minicocci
Publikováno v:
Journal of Lipid Research. 57:1097-1107
The consequences of angiopoietin-like protein 3 (ANGPTL3) deficiency on postprandial lipid and lipoprotein metabolism has not been investigated in humans. We studied 7 homozygous (undetectable circulating ANGPTL3 levels) and 31 heterozygous (50% of c
Autor:
Usama Abo Ramadan, Tuula Manninen, Esa Hohtola, Johannes Kettunen, Emmi Tikkanen, Reija Silvennoinen, Claudia P. Coomans, Leena Peltonen, Sander Kooijman, Anne M. Mäkelä, Anne Roivainen, Sjoerd A.A. van den Berg, Markus Perola, Maija Ruuth, Matti Jauhiainen, Marja-Riitta Taskinen, Antti Jula, Ilkka Seppälä, Pekka J. Karhunen, Patrick C.N. Rensen, Anu Jalanko, Miriam Lee-Rueckert, Mariëtte R. Boon, Miranda Van Eck, Christian Ehnholm, Anna Tikka, Jarkko Soronen, Krista Merikanto, Vesa M. Olkkonen, Anita M. Tuomainen, Anu Autio, Essi Kaiharju, Terho Lehtimäki, Saara Forsström, Anu Suomalainen, Ayaka Isomi, Eero Mervaala, Antti-Pekka Sarin, Ida Surakka, Veikko Salomaa, Samuli Ripatti, Jari Metso, Julia Perttilä, Aki S. Havulinna, Petri T. Kovanen, Pirkka-Pekka Laurila, Johan G. Eriksson
Publikováno v:
Science Translational Medicine, 8(323)
USF1 (upstream stimulatory factor 1) is a transcription factor associated with familial combined hyperlipidemia and coronary artery disease in humans. However, whether USF1 is beneficial or detrimental to cardiometabolic health has not been addressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8825a94114d2774164bcd385b116a19
https://doi.org/10.1126/scitranslmed.aad0015
https://doi.org/10.1126/scitranslmed.aad0015
Autor:
Jarkko Soronen, Anna Tikka, Matti Jauhiainen, Pirkka-Pekka Laurila, Jari Metso, Christian Ehnholm
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 34, Iss 6, p e00160 (2014)
Bioscience Reports, Vol 34, Iss 6, p e00160 (2014)
Homozygosity of loss-of-function mutations in ANGPTL3 (angiopoietin-like protein 3)-gene results in FHBL2 (familial combined hypolipidaemia, OMIM #605019) characterized by the reduction of all major plasma lipoprotein classes, which includes VLDL (ve
Autor:
Anna Tikka, Matti Jauhiainen
Publikováno v:
Atherosclerosis. 263:e205
Autor:
Christian Ehnholm, Anna Tikka, Jarkko Soronen, Pirkka-Pekka Laurila, Matti Jauhiainen, Jari Metso
Publikováno v:
Circulation. 130
AIMS: Homozygosity of loss-of-function mutations in ANGPTL3 -gene results in familial combined hypolipidemia (FHBL2,OMIM #605019) characterized by reduction of all major plasma lipoprotein classes VLDL, LDL, HDL and low circulating free fatty acids,
Publikováno v:
Atherosclerosis. 252:e99
Autor:
Matti Jauhiainen, Anna Tikka
Publikováno v:
Endocrine
Angiopoietin-like protein 3 (ANGPTL3) is a secretory protein regulating plasma lipid levels via affecting lipoprotein lipase- and endothelial lipase-mediated hydrolysis of triglycerides and phospholipids. ANGPTL3-deficiency due to loss-of-function mu