Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anna Thrun"'
Autor:
Anna Thrun, Annarita Patrizi, Charles S. Umbaugh, Teresa Dallinger, Sylvia Kreger, Pratik R. Patil, Claudio A. P. Joazeiro, Jia Liu, Gregory A. Cox, Yu Kigoshi-Tansho, Aitor Garzia, Thomas Tuschl
Publikováno v:
Mol Cell
Summary Incompletely synthesized nascent chains obstructing large ribosomal subunits are targeted for degradation by ribosome-associated quality control (RQC). In bacterial RQC, RqcH marks the nascent chains with C-terminal alanine (Ala) tails that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330660dd63104b424af951ecf288b3f3
https://doi.org/10.1016/j.molcel.2021.03.004
https://doi.org/10.1016/j.molcel.2021.03.004
Autor:
Anna Thrun, Claudio A. P. Joazeiro, Annika Balke, Helge Paternoga, George Tsaprailis, Christina H. Chiang, Christian M. T. Spahn, Ilka B. Bischofs, Katja Nagler, Simon Anders, Iryna Lytvynenko, Tina Müller, Julie A. Maupin-Furlow
Publikováno v:
Cell
Summary In ribosome-associated quality control (RQC), Rqc2/NEMF closely supports the E3 ligase Ltn1/listerin in promoting ubiquitylation and degradation of aberrant nascent-chains obstructing large (60S) ribosomal subunits—products of ribosome stal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55da4e94d97efe9636bb9184dbc43527
https://pubmed.ncbi.nlm.nih.gov/31155236
https://pubmed.ncbi.nlm.nih.gov/31155236
Autor:
Rosalie E. Lawrence, Roberto Zoncu, Do Jin Kim, Marie Tofaute, Ofer Moldavski, Ronja Rappold, Anna Thrun, James H. Hurley, Kelvin F. Cho
Publikováno v:
Nature cell biology
Nature cell biology, vol 20, iss 9
Nature cell biology, vol 20, iss 9
A key step in nutrient sensing is the activation of the master growth regulator, mTORC1 kinase, on the surface of lysosomes. Nutrients enable mTORC1 scaffolding by a complex composed of the Rag GTPases (Rags) and Ragulator, but the underlying mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c73a2e85c8eb4467858583c0410129
https://pubmed.ncbi.nlm.nih.gov/30061680
https://pubmed.ncbi.nlm.nih.gov/30061680