Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anna Tempczyk-Russell"'
Autor:
Hamid Razzaghi, Anna Tempczyk-Russell, Kurt Haubold, Stephanie A Santorico, Touraj Shokati, Uwe Christians, Mair E A Churchill
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e55716 (2013)
Endothelial lipase (EL) plays a pivotal role in HDL metabolism. We sought to characterize EL and its interaction with HDL as well as its natural variants genetically, functionally and structurally. We screened our biethnic population sample (n = 802)
Externí odkaz:
https://doaj.org/article/a0af3caf76124e458fa8f0afc14c1a44
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9268 (2010)
BACKGROUND: Influenza A viral surface protein, hemagglutinin, is the major target of neutralizing antibody response and hence a main constituent of all vaccine formulations. But due to its marked evolutionary variability, vaccines have to be reformul
Externí odkaz:
https://doaj.org/article/f4580092bd7a42ceb1ba61baeacb49bb
Autor:
Bradley Dean Tait, H. William Tedford, Chad A. Finkenbinder, Gary L. Benzon, Bruce A. Steinbaugh, Whitney Smith, Anna Tempczyk-Russell, Lin Bao, Robert M. Kennedy
Publikováno v:
Pesticide Biochemistry and Physiology. 106:124-140
Previously, scanning mutagenesis studies of the insecticidal peptide omega-hexatoxin-Hv1a identified a set of structural features used by the omega-hexatoxin-1 family to modulate insect calcium channels. These structural features were re-purposed as
Autor:
Yali Deng, Patrick M O'Connor, Chen-Chen Kan, Pamela Myers, James Register, Luo Chun, Stephen Margosiak, Binh Nguyen, Kevin Ryan, Ping Chen, Karen Lundgren, Anna Tempczyk-Russell
Publikováno v:
Cell. 100(6):681-692
The checkpoint kinase Chk1 is an important mediator of cell cycle arrest following DNA damage. The 1.7 Å resolution crystal structures of the human Chk1 kinase domain and its binary complex with an ATP analog has revealed an identical open kinase co
Autor:
Michele Ann Mctigue, Michael R Gehring, Chris Pinko, J. Ernest Villafranca, Chen-Chen Kan, Camran V Parast, Krzysztof Appelt, Richard E. Showalter, Barbara Mroczkowski, John A Wickersham, Anna Tempczyk-Russell
Publikováno v:
Structure. 7:319-330
Background: Angiogenesis is involved in tumor growth, macular degeneration, retinopathy and other diseases. Vascular endothelial growth factor (VEGF) stimulates angiogenesis by binding to specific receptors (VEGFRs) on the surface of vascular endothe
Autor:
James Arthur Thomson, Richard E. Showalter, J. Ernest Villafranca, Anna Tempczyk-Russell, Melwyn A. Abreo, Laura A. Pelletier, Charles R. Kissinger, Bin Li, Jerry J. Meng, Stephen Margosiak, Charles S. Agree, Robert M. Aust, Darin Vanderpool, Paul A. Rejto
Publikováno v:
Journal of molecular biology. 342(3)
The enzyme 17beta-hydroxysteroid dehydrogenase type 10 (HSD10), also known as amyloid beta-peptide-binding alcohol dehydrogenase (ABAD), has been implicated in the development of Alzheimer's disease. This protein, a member of the short-chain dehydrog
Autor:
Touraj Shokati, Anna Tempczyk-Russell, Mair E. A. Churchill, Stephanie A. Santorico, Uwe Christians, Hamid Razzaghi, Kurt W. Haubold
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e55716 (2013)
PLoS ONE, Vol 8, Iss 3, p e55716 (2013)
Endothelial lipase (EL) plays a pivotal role in HDL metabolism. We sought to characterize EL and its interaction with HDL as well as its natural variants genetically, functionally and structurally. We screened our biethnic population sample (n = 802)
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9268 (2010)
PLoS ONE
PLoS ONE
Background Influenza A viral surface protein, hemagglutinin, is the major target of neutralizing antibody response and hence a main constituent of all vaccine formulations. But due to its marked evolutionary variability, vaccines have to be reformula