Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anna Tanka-Salamon"'
Autor:
Miklós Lovas, Anna Tanka-Salamon, László Beinrohr, István Voszka, László Szabó, Kinga Molnár, Krasimir Kolev
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Introduction Beyond the three-dimensional fibrin network, the mechanical and lytic stability of thrombi is supported by the matrix of neutrophil extracellular traps (NETs) composed of polyanionic DNA meshwork with attached proteins including polycati
Externí odkaz:
https://doaj.org/article/2a70778159594591b67a818d02ee6040
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167806 (2016)
Upon platelet activation, free fatty acids are released at the stage of thrombus formation, but their effects on fibrin formation are largely unexplored. Our objective was to characterize the kinetic effects of fatty acids on thrombin activity, as we
Externí odkaz:
https://doaj.org/article/ef450e55706e428bbf9b3e4a5e1af14a
Autor:
László Szabó, Anna Tanka-Salamon, Attila Bóta, Nóra Balázs, Zoltán Varga, Colin Longstaff, Erzsébet Komorowicz, Krasimir Kolev
Publikováno v:
Journal of Thrombosis and Haemostasis. 19:1307-1318
Background Neutrophil extracellular traps (NETs) containing DNA and histones are expelled from neutrophils in infection and thrombosis. Heparins, anticoagulant polyanions, can neutralize histones with a potential therapeutic advantage in sepsis. Poly
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2017 (2017)
BioMed Research International, Vol 2017 (2017)
Protease encapsulation and its targeted release in thrombi may contribute to the reduction of haemorrhagic complications of thrombolysis. We aimed to prepare sterically stabilized trypsin-loaded liposomes (SSLT) and characterize their structure and f
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167806 (2016)
PLoS ONE
PLoS ONE
Upon platelet activation, free fatty acids are released at the stage of thrombus formation, but their effects on fibrin formation are largely unexplored. Our objective was to characterize the kinetic effects of fatty acids on thrombin activity, as we
Publikováno v:
Thrombosis and Haemostasis. 103:291-298
SummaryThe formation of platelet-rich thrombi under high shear rates requires both fibrinogen and von Willebrand factor (VWF) as molecular adhesives between platelets. We attempted to describe the role of VWF as a potential substrate and modulator of
Autor:
Krasimir Kolev, Raymund Machovich, Veronika Judit Varga-Szabó, Á. Farkas, Imre Varjú, Colin Longstaff, László Szabó, Anna Tanka-Salamon
Publikováno v:
Thrombosis and haemostasis. 113(6)
SummaryIn response to various inflammatory stimuli, neutrophils secrete neutrophil extracellular traps (NETs), web-like meshworks of DNA, histones and granular components forming supplementary scaffolds in venous and arterial thrombi. Isolated DNA an
Publikováno v:
The Febs Journal
Thrombi, which are dissolved primarily by plasmin (EC 3.4.21.7.), contain up to millimolar concentrations of fatty acids and these are known to affect the action of the protease. In the present study the modulation of plasmin activity was characteriz
Autor:
Krasimir Kolev, Judit Gombás, Anna Tanka-Salamon, Zoltán Zsolt Nagy, Judit Skopál, Raymund Machovich
Publikováno v:
ResearcherID
Because both immunoglobulin G (IgG) and phospholipids interfere with fibrinolysis, their combined modulating effects were investigated in experimental models of three consecutive steps of the fibrinolytic process [diffusion of tissue-type plasminogen