Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anna Sofie Holm Jonassen"'
Autor:
Monika Mortensen, Inger Ødum Nielsen, Kenji Maeda, Anna Sofie Holm Jonassen, Mesut Bilgin, Marja Jäättelä, Line Groth-Pedersen, Kjeld Schmiegelow, Jano Dicroce-Giacobini
Publikováno v:
Metabolomics. 16
Repurposing of cationic amphiphilic drugs (CADs) emerges as an attractive therapeutic solution against various cancers, including leukemia. CADs target lysosomal lipid metabolism and preferentially kill cancer cells via induction of lysosomal membran
Autor:
Saara Hämälistö, Jennifer Kricker, Søren Høgh, Siri Amanda Tvingsholm, Sonja Aits, Anne-Marie Ellegaard, Bin Liu, Monika Mortensen, Anna Sofie Holm Jonassen, Irina Gromova, Marja Jäättelä, Thomas Farkas, Elisabeth Corcelle-Termeau
Publikováno v:
Autophagy. 11(8)
Lysosomal membrane permeabilization (LMP) contributes to tissue involution, degenerative diseases, and cancer therapy. Its investigation has, however, been hindered by the lack of sensitive methods. Here, we characterize and validate the detection of