Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anna Sinistro"'
Autor:
Giovanni Di Zenzo, Michael Hertl, Giulia Di Lullo, Bungo Ohyama, Giovanna Zambruno, Jerry Sloostra, Valentina Calabresi, Biagio Didona, Anna Sinistro, Giuseppe Cianchini, Antonio Lanzavecchia, Masayuki Amagai, Davide Corti, Rüdiger Eming, Federica Sallusto, Fabrizia Vanzetta, Takashi Hashimoto
Publikováno v:
Journal of Clinical Investigation; Vol 122
Pemphigus vulgaris (PV) is an autoimmune blistering disease of skin and mucous membranes caused by autoantibodies to the desmoglein (DSG) family proteins DSG3 and DSG1, leading to loss of keratinocyte cell adhesion. To learn more about pathogenic PV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ab1ff753fa72696eecb7aa467d29a6
http://doc.rero.ch/record/326692/files/DiZenzo_JCI_2012.pdf
http://doc.rero.ch/record/326692/files/DiZenzo_JCI_2012.pdf
Autor:
Laura Giurato, Erika Vainieri, Francesca Spasaro, Luigi Uccioli, Cristiana Almerighi, Alberto Bergamini, Anna Sinistro, Antonella Cavazza, G. Rocchi, Chiara Ciaprini, Valeria Ruotolo
Publikováno v:
Diabetes Care
OBJECTIVEDespite increased information on the importance of an inappropriate inflammatory response in the acute Charcot process, there has been no previous attempt to define the specific pathways that mediate its pathogenesis. Here, the role played b
Autor:
Liliana Guerra, Biagio Didona, Daniele Castiglia, Anna Sinistro, Vittoria Proto, Giovanna Zambruno, Paola Fortugno
Publikováno v:
The Journal of dermatology. 42(8)
Netherton syndrome (NS) is a rare genetic disease presenting with ichthyosiform erythroderma, hair alterations and atopy. NS is due to SPINK5 gene mutations, which cause absent or decreased expression of the encoded protein lymphoepithelial Kazal-typ
Autor:
F. Lolicato, Giovanna Zambruno, C. Cerasaro, Emanuele Cozzani, Anna Sinistro, Andrea Parodi, G. Di Zenzo, Biagio Didona, M. Muscianese, Valentina Calabresi
Background Epidermolysis bullosa acquisita (EBA) is an autoimmune blistering disease characterized by tissue-bound and circulating autoantibodies to the dermal-epidermal junction. The autoantibody target is type VII collagen (Col VII) which is involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c43f07f0743d820170d8f8d79a8055
http://hdl.handle.net/11567/773434
http://hdl.handle.net/11567/773434
Autor:
Cristiana Almerighi, Francesca Leonardis, Eleonora Baffari, Diego Fiume, Francesca Calò-Carducci, Giordana Caiazzo, Anna Sinistro, Alberto Bergamini, Silvia Natoli
Sepsis-induced immune dysfunction is a complex phenomenon that involves both innate and adaptive responses. Upregulation of the inhibitor receptor named immunoglobulin like transcript 4 (ILT4) is crucial to the tolerogenic function of monocytes. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5fdca4ab1c240edf8b3cb6f295e51a
http://hdl.handle.net/2108/106140
http://hdl.handle.net/2108/106140
Autor:
Mario Angelico, Raffaella Lionetti, Alberto Bergamini, Anna Sinistro, Cristiana Almerighi, Giuseppe Tisone, Ilaria Lenci, Laura Tariciotti
Background Aim of the present study was to investigate whether 1,25(OH)(2)D(3) (Vitamin D3) modulates T lymphocyte functions in patients transplanted for hepatitis C virus-related cirrhosis. Methods Sixteen patients and ten healthy subjects were inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a0f7dbf64f6b3dd8c39fd6559daf67
http://hdl.handle.net/2108/77107
http://hdl.handle.net/2108/77107
Autor:
F Leonardis, Cristiana Almerighi, V Tsekeuli, GC Caiazza, F Calo'-Carducci, DF Fiume, E Baffari, AB Bergamini, S Natoli, Anna Sinistro
Publikováno v:
Critical Care
Introduction Despite intense efforts, sepsis remains a serious clinical problem,accounting for thousands of deaths every year. Many findings have shown that immune dysfunction in septic patients plays a very important role. Thus, a better understandi
Autor:
Francesca Calò-Carducci, Alberto Bergamini, Sara Di Fino, Silvia Natoli, Anna Sinistro, Cristiana Almerighi, Chiara Ciaprini, G. Rocchi, Emanuele Sussarello
It has been suggested that a defective adaptive immune response contributes to septic immunosuppression. Here, the response of monocytes to CD40 ligand (CD40L) for patients with sepsis due to infection with gram-negative organisms has been analyzed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6f70594e31687a7ac39409af1b6b2b
http://hdl.handle.net/2108/48124
http://hdl.handle.net/2108/48124
Autor:
Giuseppe La Regina, Alberto Bergamini, Samantha Zanoli, Giovanni Maga, Antonella Cavazza, Ettore Novellino, Romano Silvestri, F. Piscitelli, Antonio Coluccia, Marino Artico, Alberta Samuele, Anna Sinistro
Publikováno v:
Journal of medicinal chemistry. 50(20)
Indolyl aryl sulfones bearing the 4,5-difluoro (10) or 5-chloro-4-fluoro (16) substitution pattern at the indole ring were potent inhibitors of HIV-1 WT and the NNRTI-resistant strains Y181C and K103N−Y181C. These compounds were highly effective ag
Autor:
G. Rocchi, Alberto Bergamini, Silvia Natoli, Emanuele Sussarello, Anna Sinistro, M. Capozzi, Francesca Bolacchi, Chiara Ciaprini, Francesca Ippolita Calò Carducci, Cristiana Almerighi
Publikováno v:
Immunology. 122(3)
Polymicrobial sepsis induces the suppression of macrophage function as determined by a reduction of pro-inflammatory cytokine production upon re-exposure to lipopolysaccharide (LPS) in vitro. Here, we examined whether macrophages were refractory to o