Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Anna Sherwood"'
Autor:
Travers Ching, Megan E. Duncan, Tera Newman-Eerkes, Mollie M. E. McWhorter, Jeffrey M. Tracy, Michelle S. Steen, Ryan P. Brown, Srivatsa Venkatasubbarao, Nicholas K. Akers, Marissa Vignali, Martin E. Moorhead, Drew Watson, Ryan O. Emerson, Tobias P. Mann, B. Melina Cimler, Pamela L. Swatkowski, Ilan R. Kirsch, Charles Sang, Harlan S. Robins, Bryan Howie, Anna Sherwood
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background The clonoSEQ® Assay (Adaptive Biotechnologies Corporation, Seattle, USA) identifies and tracks unique disease-associated immunoglobulin (Ig) sequences by next-generation sequencing of IgH, IgK, and IgL rearrangements and IgH-BCL1
Externí odkaz:
https://doaj.org/article/f4765b6429fd4f42acca9201ac81c886
Autor:
Harlan Robins, Brent L. Wood, David Williamson, Christopher Carlson, Ilan Kirsch, Mark Rieder, Jennifer Vogt, Bryan Howie, Anne Angiolillo, Mignon L. Loh, Anna Sherwood, Ryan O. Emerson, David Wu
Purpose: High-throughput sequencing (HTS) of immunoglobulin heavy-chain genes (IGH) in unselected clinical samples for minimal residual disease (MRD) in B lymphoblastic leukemia (B-ALL) has not been tested. As current MRD-detecting methods such as fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b66a20171130a818004d03c57667ff3
https://doi.org/10.1158/1078-0432.c.6522876.v1
https://doi.org/10.1158/1078-0432.c.6522876.v1
Autor:
Harlan Robins, Brent L. Wood, David Williamson, Christopher Carlson, Ilan Kirsch, Mark Rieder, Jennifer Vogt, Bryan Howie, Anne Angiolillo, Mignon L. Loh, Anna Sherwood, Ryan O. Emerson, David Wu
Supplementary Figure 6. Pre-treatment flow cytometry with post-treatment MRD by HTS identified in a triple flow cytometry-sorted fraction of mature B cells. To determine if mpFC was missing MRD as compared to HTS, we evaluated 10 additional samples b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fd63075bde2a4252c7e1a272e6cf91
https://doi.org/10.1158/1078-0432.22454928
https://doi.org/10.1158/1078-0432.22454928
Autor:
Cheryl L. Day, Willie J. Swanson, Chetan Seshadri, Ryan O. Emerson, Harlan Robins, Philip Bradley, Anna Sherwood, William S DeWitt, Damien B. Wilburn, Thomas J. Scriba, Krystle K. Q. Yu, Marissa Vignali
Publikováno v:
The Journal of Immunology. 201:888-896
Human T cells that recognize lipid Ags presented by highly conserved CD1 proteins often express semi-invariant TCRs, but the true diversity of lipid Ag–specific TCRs remains unknown. We use CD1b tetramers and high-throughput immunosequencing to ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a57f961e8b68dc89b6d8d240b407e616
https://doi.org/10.4049/jimmunol.1800186
https://doi.org/10.4049/jimmunol.1800186
Autor:
Harlan Robins, Nathaniel D. Chu, Anna Sherwood, Michael E. Birnbaum, Eric J. Alm, Ryan O. Emerson, Haixin Sarah Bi
Publikováno v:
BMC Immunology, Vol 20, Iss 1, Pp 1-12 (2019)
BMC Immunology
BMC Immunology
Background The adaptive immune system maintains a diversity of T cells capable of recognizing a broad array of antigens. Each T cell’s specificity for antigens is determined by its T cell receptors (TCRs), which together across all T cells form a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baaafe19426d4cd36f4c5f91e96ab1d
https://doi.org/10.1186/s12865-019-0300-5
https://doi.org/10.1186/s12865-019-0300-5
Autor:
Harlan Robins, Eric J. Alm, Ryan O. Emerson, Michael E. Birnbaum, Anna Sherwood, Nathaniel D. Chu, Haixin Sarah Bi
BackgroundThe adaptive immune system maintains a diversity of T cells capable of recognizing a broad array of antigens. Each T cell’s specificity and affinity for antigens is determined by its T cell receptors (TCRs), which together across all T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61338e70dd30023cce8de60d28583df
https://doi.org/10.1101/262667
https://doi.org/10.1101/262667
Publikováno v:
Inflammatory Bowel Diseases. 21:19-30
FOXP3 regulatory T cell prevent inflammation but are paradoxically increased in ulcerative colitis (UC). Local T-cell activation has been hypothesized to account for increased FOXP3 expression in colon lamina propria (LP) T cells.To see if human FOXP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfe49d999201efca0c86441a2620e31
https://doi.org/10.1097/mib.0000000000000242
https://doi.org/10.1097/mib.0000000000000242
Autor:
Harlan Robins, Stephen C. DeRosa, Chetan Seshadri, Cheryl L. Day, Damien B. Wilburn, Marissa Vignali, Krystle K. Quan, Thomas J. Scriba, Willie J. Swanson, Ryan O. Emerson, William S DeWitt, Anna Sherwood
Peptide-specific T cells that are restricted by highly polymorphic major histocompatibility complex (MHC) proteins express diverse T-cell receptors (TCRs) that are rarely shared among unrelated individuals. T-cells can also recognize bacterial lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113554cf6bbfaf8ce7cbe249d45408e4
https://doi.org/10.1101/123174
https://doi.org/10.1101/123174
Autor:
Ilan R. Kirsch, Christopher S. Carlson, Mark J. Rieder, Bryan Howie, Harlan Robins, Anne L. Angiolillo, Anna Sherwood, Jennifer Vogt, Brent L. Wood, David Williamson, David Wu, Ryan O. Emerson, Mignon L. Loh
Publikováno v:
Clinical Cancer Research. 20:4540-4548
Purpose: High-throughput sequencing (HTS) of immunoglobulin heavy-chain genes (IGH) in unselected clinical samples for minimal residual disease (MRD) in B lymphoblastic leukemia (B-ALL) has not been tested. As current MRD-detecting methods such as fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1373458028a5ab189d722cbb25374e3
https://doi.org/10.1158/1078-0432.ccr-13-3231
https://doi.org/10.1158/1078-0432.ccr-13-3231
Autor:
Jason H. Bielas, Christopher S. Carlson, Muneesh Tewari, David Williamson, Anna Sherwood, Harlan Robins, Charles W. Drescher, Jamie Guenthoer, Ryan O. Emerson, Mark J. Rieder
Publikováno v:
The Journal of Pathology. 231:433-440
The cellular adaptive immune system mounts a response to many solid tumours mediated by tumour-infiltrating T lymphocytes (TILs). Basic measurements of these TILs, including total count, show promise as prognostic markers for a variety of cancers, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79080de89c6dfca5c5a3e84464ada9c
https://doi.org/10.1002/path.4260
https://doi.org/10.1002/path.4260