Induced pluripotent stem cell-derived lung alveolar epithelial type II cells reduce damage in bleomycin-induced lung fibrosis

Autor: Belén Alvarez-Palomo, Luis Ignacio Sanchez-Lopez, Yuben Moodley, Michael J. Edel, Anna Serrano-Mollar

Publikováno v: Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)

Abstract Background Idiopathic pulmonary fibrosis is a chronic, progressive, and severe disease with a limited response to currently available therapies. Epithelial cell injury and failure of appropriate healing or regeneration are central to the pat

Externí odkaz: https://doaj.org/article/93295ee3147b4f0594cabc1e59a4d8e1

Differences and Similarities between the Lung Transcriptomic Profiles of COVID-19, COPD, and IPF Patients: A Meta-Analysis Study of Pathophysiological Signaling Pathways

Autor: Daniel Aguilar, Adelaida Bosacoma, Isabel Blanco, Olga Tura-Ceide, Anna Serrano-Mollar, Joan Albert Barberà, Victor Ivo Peinado

Publikováno v: Life, Vol 12, Iss 6, p 887 (2022)

Coronavirus disease 2019 (COVID-19) is a pandemic respiratory disease associated with high morbidity and mortality. Although many patients recover, long-term sequelae after infection have become increasingly recognized and concerning. Among other seq

Externí odkaz: https://doaj.org/article/1b6a03a8fdf84b1e8e7bcfa8dde1c19e

PlyKp104, a Novel Phage Lysin for the Treatment of Klebsiella pneumoniae, Pseudomonas aeruginosa, and Other Gram-Negative ESKAPE Pathogens

Autor: Chad W. Euler, Assaf Raz, Anaise Hernandez, Anna Serrano, Siyue Xu, Martin Andersson, Geng Zou, Yue Zhang, Vincent A. Fischetti, Jinquan Li

Publikováno v: Antimicrobial Agents and Chemotherapy. 67

Klebsiella pneumoniae and Pseudomonas aeruginosa are two leading causes of burn and wound infections, pneumonia, urinary tract infections, and more severe invasive diseases, which are often multidrug resistant (MDR) or extensively drug resistant. Due

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74e06c96ed86f583fcd3c12e7e37c7ab
https://doi.org/10.1128/aac.01519-22

Alveolar Type II Cells or Mesenchymal Stem Cells: Comparison of Two Different Cell Therapies for the Treatment of Acute Lung Injury in Rats

Autor: Raquel Guillamat-Prats, Marta Camprubí-Rimblas, Ferranda Puig, Raquel Herrero, Neus Tantinyà, Anna Serrano-Mollar, Antonio Artigas

Publikováno v: Cells, Vol 9, Iss 8, p 1816 (2020)

The use of cell therapies has recently increased for the treatment of pulmonary diseases. Mesenchymal stem/stromal cells (MSCs) and alveolar type II cells (ATII) are the main cell-based therapies used for the treatment of acute respiratory distress s

Externí odkaz: https://doaj.org/article/b14a0f2580e14bdb8c01c119ea39ccde

Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue cells

Autor: Vicenç Falcó, Núria Massana, Anna Serrano-Mollar, David Perea, Benjamin Trinité, José Alcamí, María José Soler, Javier García-Pérez, Maria J. Buzon, Marina Suppi, Julià Blanco, Meritxell Genescà, Ander Vergara, Judith Grau-Expósito, Joel Rosado

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS Pathogens, Vol 18, Iss 1, p e1010171 (2022)
PLoS Pathogens
Repisalud
Instituto de Salud Carlos III (ISCIII)

The development of physiological models that reproduce SARS-CoV-2 infection in primary human cells will be instrumental to identify host-pathogen interactions and potential therapeutics. Here, using cell suspensions directly from primary human lung t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2534a4ca5c5b61b4ab8b09c1474fc5d1
http://hdl.handle.net/10261/268646