Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Anna Sebestyen"'
Autor:
Borbála Péterffy, Tamás J. Nádasi, Szilvia Krizsán, Anna Horváth, Ágnes Márk, Gábor Barna, Botond Timár, Laura Almási, Judit Müller, Krisztina Csanádi, Anna Rakonczai, Zsolt Nagy, Krisztián Kállay, Gabriella Kertész, Gergely Kriván, Monika Csóka, Anna Sebestyén, Ágnes F. Semsei, Gábor T. Kovács, Dániel J. Erdélyi, Csaba Bödör, Bálint Egyed, Donát Alpár
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Despite remarkable improvements in the survival of pediatric acute lymphoblastic leukemia (ALL), sensitive detection and clinical management of central nervous system leukemia (CNSL) are still immensely challenging. Blast cells residing in t
Externí odkaz:
https://doaj.org/article/e80a4879cb004880933bc93142da0376
Autor:
Dániel Sztankovics, Fatime Szalai, Dorottya Moldvai, Titanilla Dankó, Noémi Nagy, Judit Pápay, András Khoór, Ildikó Krencz, Anna Sebestyén
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 4, Pp 151468- (2024)
Small cell lung carcinoma (SCLC) is a highly malignant cancer with early metastatic dissemination and poor clinical outcomes. Mutations in the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway, i
Externí odkaz:
https://doaj.org/article/330b1db415774fd19967c36c4c2a7cae
Publikováno v:
Cancer and Metastasis Reviews. 40:1141-1157
Small cell lung carcinoma (SCLC) is characterized by high metastatic rate and poor prognosis. The platinum-based chemotherapy still represents the backbone of the therapy; however, acquired resistance develops almost in all patients. Although SCLC ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdec464d65d10cd3e956749157dd6f17
https://doi.org/10.1007/s10555-021-10012-4
https://doi.org/10.1007/s10555-021-10012-4
Autor:
Ildikó Krencz, Dániel Sztankovics, Anna Sebestyén, Judit Pápay, Titanilla Dankó, Dorottya Moldvai, Elmar Lutz, Andras Khoor
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
RICTOR gene, which encodes the scaffold protein of mTORC2, can be amplified in various tumor types, including squamous cell carcinoma (SCC) of the lung. RICTOR amplification can lead to hyperactivation of mTORC2 and may serve as a targetable genetic
Externí odkaz:
https://doaj.org/article/fc3d684fdaff4c96b26aca54c6f8cf21
Autor:
Dániel Sztankovics, Ildikó Krencz, Dorottya Moldvai, Titanilla Dankó, Ákos Nagy, Noémi Nagy, Gábor Bedics, András Rókusz, Gergő Papp, Anna-Mária Tőkés, Judit Pápay, Zoltán Sápi, Katalin Dezső, Csaba Bödör, Anna Sebestyén
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Alterations in mTOR signalling molecules, including RICTOR amplification, have been previously described in many cancers, particularly associated with poor prognosis. In this study, RICTOR copy number variation (CNV) results of diagnostic ne
Externí odkaz:
https://doaj.org/article/d916b489a8c1402d8ae70fac8a29c2d2
Autor:
Anna Sebestyen, Attila Patocs, Gergely Sváb, István Likó, Barbara Mátyási, Anil Mehta, Laszlo Tretter, Attila L. Kovács, Krisztina Takács-Vellai, Eva Saskoi, Gabor Nyiro, Balázs Sarkadi, Katalin Mészáros, László Patthy, Zoltán Hujber
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cfcf2cbf629eaa894891a40b2beb116
https://doi.org/10.1530/endoabs.63.p444
https://doi.org/10.1530/endoabs.63.p444
Autor:
Peter Igaz, Ildikó Krencz, Attila Patocs, Christos Chinopoulos, Katalin Borka, Anna Sebestyen, Balázs Sarkadi, Sara Zakarias, Zoltán Hujber, Judit Pápay, Gabor Barja, Katalin Mészáros, Miklos Toth, Kinga Németh
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c70881f751901ec9e0f03e2c4693a9f4
https://doi.org/10.1530/endoabs.63.gp6
https://doi.org/10.1530/endoabs.63.gp6
Autor:
Dániel Sztankovics, Dorottya Moldvai, Gábor Petővári, Titanilla Dankó, Fatime Szalai, Risa Miyaura, Viktória Varga, Noémi Nagy, Gergő Papp, Judit Pápay, Ildikó Krencz, Anna Sebestyén
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
The increasing knowledge of molecular alterations in malignancies, including mutations and regulatory failures in the mTOR (mechanistic target of rapamycin) signaling pathway, highlights the importance of mTOR hyperactivity as a validated target in c
Externí odkaz:
https://doaj.org/article/50d1c7653f534df2bad19730c717af5b
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Externí odkaz:
https://doaj.org/article/fdf98016123f484ebafd36094ae94e73
Autor:
Viktória Zsiros, Nikolett Dóczi, Gábor Petővári, Alexandra Pop, Zsófia Erdei, Anna Sebestyén, Anna L. Kiss
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Previously, we showed that after Freund’s adjuvant-induced peritonitis, rat mesothelial cells regain their epithelial phenotype through mesenchymal-epithelial transition (MET) accompanied by autophagy. Since bone morphogenetic proteins (BM
Externí odkaz:
https://doaj.org/article/f29579322946424fb3b8d3485f892a0e