Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Anna Santamaria"'
Autor:
Melissa Bradbury, Eva Borràs, Marta Vilar, Josep Castellví, José Luis Sánchez-Iglesias, Assumpció Pérez-Benavente, Antonio Gil-Moreno, Anna Santamaria, Eduard Sabidó
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background High-grade serous carcinoma (HGSC) is the most common and deadly subtype of ovarian cancer. Although most patients will initially respond to first-line treatment with a combination of surgery and platinum-based chemotherapy, up to
Externí odkaz:
https://doaj.org/article/6a64418d00f5404f8d89c550c4e06857
Autor:
Juan Morote, Miriam Campistol, Marina Triquell, Anna Celma, Lucas Regis, Inés de Torres, Maria E. Semidey, Richard Mast, Anna Santamaria, Jacques Planas, Enrique Trilla
Publikováno v:
European Urology Open Science, Vol 37, Iss , Pp 38-44 (2022)
Background: Prostate Imaging-Reporting and Data System (PI-RADS) category 3 is a challenging scenario for detection of clinically significant prostate cancer (csPCa) and some tools can improve the selection of appropriate candidates for prostate biop
Externí odkaz:
https://doaj.org/article/cd89f67328fe45c8ab108a9618157aaf
Autor:
Melissa Bradbury, Eva Borràs, Josep Castellví, Olga Méndez, José Luis Sánchez-Iglesias, Assumpció Pérez-Benavente, Antonio Gil-Moreno, Eduard Sabidó, Anna Santamaria
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Despite recent advances in the management of BRCA1 mutated high-grade serous ovarian cancer (HGSC), the physiology of these tumors remains poorly understood. Here we provide a comprehensive molecular understanding of the signaling processes
Externí odkaz:
https://doaj.org/article/2bd7a5804664497697fd7a4a543dafff
Autor:
Marc Masanas, Nuria Masiá, Leticia Suárez‐Cabrera, Mireia Olivan, Aroa Soriano, Blanca Majem, Laura Devis‐Jauregui, Rebeca Burgos‐Panadero, Carlos Jiménez, Pau Rodriguez‐Sodupe, Ariadna Boloix, Ignasi Toledano, Gabriela Guillén, Alexandra Navarro, David Llobet‐Navas, Alberto Villanueva, Josep Sánchez de Toledo, Josep Roma, Rosa Noguera, Lucas Moreno, Rolf Krauss, Soledad Gallego, Anna Santamaria, Miguel F. Segura
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 10, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/0f523fbf09f54b039035764c35d19a62
Autor:
Cinthia Aguilera, Stefan Hümmer, Marc Masanas, Elisabeth Gabau, Miriam Guitart, A. Arockia Jeyaprakash, Miguel F. Segura, Anna Santamaria, Anna Ruiz
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
KIF1A is a microtubule-dependent motor protein responsible for fast anterograde transport of synaptic vesicle precursors in neurons. Pathogenic variants in KIF1A have been associated with a wide spectrum of neurological disorders. Here, we report a p
Externí odkaz:
https://doaj.org/article/a076fd12eddd46a3a646d90898b8af95
Autor:
Yann Thomas, Luca Cirillo, Costanza Panbianco, Lisa Martino, Nicolas Tavernier, Françoise Schwager, Lucie Van Hove, Nicolas Joly, Anna Santamaria, Lionel Pintard, Monica Gotta
Publikováno v:
Cell Reports, Vol 15, Iss 3, Pp 510-518 (2016)
The conserved Bora protein is a Plk1 activator, essential for checkpoint recovery after DNA damage in human cells. Here, we show that Bora interacts with Cyclin B and is phosphorylated by Cyclin B/Cdk1 at several sites. The first 225 amino acids of B
Externí odkaz:
https://doaj.org/article/924201aa600c4cd9aa9a611934c30191
Autor:
Manuel Bauer, Erik Ahrné, Anna P. Baron, Timo Glatter, Luca L. Fava, Anna Santamaria, Erich A. Nigg, Alexander Schmidt
Publikováno v:
Data in Brief, Vol 5, Iss C, Pp 297-304 (2015)
The data described here provide a systematic performance evaluation of popular data-dependent (DDA) and independent (DIA) mass spectrometric (MS) workflows currently used in quantitative proteomics. We assessed the limits of identification, quantific
Externí odkaz:
https://doaj.org/article/0d55c91f6eba43eabb7c82c9c938c165
Autor:
Marina Rosso, Blanca Majem, Laura Devis, Lara Lapyckyj, María José Besso, Marta Llauradó, María Florencia Abascal, María Laura Matos, Lucia Lanau, Josep Castellví, José Luis Sánchez, Asunción Pérez Benavente, Antonio Gil-Moreno, Jaume Reventós, Anna Santamaria Margalef, Marina Rigau, Mónica Hebe Vazquez-Levin
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184439 (2017)
Ovarian cancer (OC) is the fifth cancer death cause in women worldwide. The malignant nature of this disease stems from its unique dissemination pattern. Epithelial-to-mesenchymal transition (EMT) has been reported in OC and downregulation of Epithel
Externí odkaz:
https://doaj.org/article/cb3338c313da4628b5b3f0128c769cfa
Autor:
Ana M Rojas, Anna Santamaria, Rainer Malik, Thomas Skøt Jensen, Roman Körner, Ian Morilla, David de Juan, Martin Krallinger, Daniel Aaen Hansen, Robert Hoffmann, Jonathan Lees, Adam Reid, Corin Yeats, Anja Wehner, Sabine Elowe, Andrew B Clegg, Søren Brunak, Erich A Nigg, Christine Orengo, Alfonso Valencia, Juan A G Ranea
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31813 (2012)
The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments. However, because of its dynami
Externí odkaz:
https://doaj.org/article/70153f80d41f49f28dad5fc2de9963d1
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18793 (2011)
BACKGROUND: Members of the Mps1 kinase family play an essential and evolutionarily conserved role in the spindle assembly checkpoint (SAC), a surveillance mechanism that ensures accurate chromosome segregation during mitosis. Human Mps1 (hMps1) is hi
Externí odkaz:
https://doaj.org/article/0e362e332b5e4d3bb45fcdb19fe47f9b