Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anna Sande"'
Autor:
Edith Van Esch, Ziena Abdulrahman, Natasja Hendriks, Arnold Jan Kruse, Antonios Somarakis, Anna Sande, Heleen Van Beekhuizen, Jurgen Piek, Noel De Miranda, Loes Kooreman, Brigitte Slangen, Sjoerd Van Der Burg, Peggy De Vos Van Steenwijk
Publikováno v:
E-Posters.
Publikováno v:
Frontiers in Climate, Vol 5 (2024)
Climate change adaptation is a maturing field of research imbued with many complexities and tensions. In this article, we outline five tensions that we observe in our own adaptation research. These are between: adaptation as a research topic and prac
Externí odkaz:
https://doaj.org/article/fdd4f1d18aae4ad69d753bb50aec183d
Autor:
Alessandro Mega, Aman Mebrahtu, Gustav Aniander, Eva Ryer, Annette Sköld, Anna Sandegren, Eva Backström Rydin, Johan Rockberg, Arne Östman, Fredrik Y. Frejd
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTCD40 agonism by systemic administration of CD40 monoclonal antibodies has been explored in clinical trials for immunotherapy of cancer, uncovering enormous potential, but also dosing challenges in terms of systemic toxicity. CD40-dependent ac
Externí odkaz:
https://doaj.org/article/5fcf495d262941deb28a289c2152f86b
Autor:
Veronica Gast, Anna Sandegren, Finn Dunås, Siri Ekblad, Rezan Güler, Staffan Thorén, Marta Tous Mohedano, Mikael Molin, Martin K. M. Engqvist, Verena Siewers
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Background Affibody molecules are synthetic peptides with a variety of therapeutic and diagnostic applications. To date, Affibody molecules have mainly been produced by the bacterial production host Escherichia coli. There is an interest in
Externí odkaz:
https://doaj.org/article/97741660c2d64e549d4f8423f1d14931
Autor:
Julen Goikolea, Gorka Gerenu, Makrina Daniilidou, Francesca Mangialasche, Patrizia Mecocci, Tiia Ngandu, Juha Rinne, Alina Solomon, Miia Kivipelto, Angel Cedazo-Minguez, Anna Sandebring-Matton, Silvia Maioli
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background Thioredoxin-80 (Trx80) is a cleavage product from the redox-active protein Thioredoxin-1 and has been previously described as a pro-inflammatory cytokine secreted by immune cells. Previous studies in our group reported that Trx80
Externí odkaz:
https://doaj.org/article/79f285263a064cd2a9cf39e3ec800881
Autor:
Anna Sandebring-Matton, Julen Goikolea, Ingemar Björkhem, Laura Paternain, Nina Kemppainen, Tiina Laatikainen, Tiia Ngandu, Juha Rinne, Hilkka Soininen, Angel Cedazo-Minguez, Alina Solomon, Miia Kivipelto
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2021)
Abstract Background 27-Hydroxycholesterol (27-OH), the main circulating oxysterol in humans and the potential missing link between peripheral hypercholesterolemia and Alzheimer’s disease (AD), has not been investigated previously in relation to cog
Externí odkaz:
https://doaj.org/article/331e6ffc2e9744dcabc5a657dfe423ad
Autor:
Jolanta L. Lundgren, Lina Vandermeulen, Anna Sandebring-Matton, Saheeb Ahmed, Bengt Winblad, Monica Di Luca, Lars O. Tjernberg, Elena Marcello, Susanne Frykman
Publikováno v:
BMC Neuroscience, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Synaptic degeneration and accumulation of amyloid β-peptides (Aβ) are hallmarks of the Alzheimer diseased brain. Aβ is synaptotoxic and produced by sequential cleavage of the amyloid precursor protein (APP) by the β-secretase
Externí odkaz:
https://doaj.org/article/015fd95e45944b449a0bb53f742f6273
Autor:
Anna Sandebring-Matton, Michael Axenhus, Nenad Bogdanovic, Bengt Winblad, Sophia Schedin-Weiss, Per Nilsson, Lars O. Tjernberg
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Novel insights on proteins involved in Alzheimer’s disease (AD) are needed. Since multiple cell types and matrix components are altered in AD, bulk analysis of brain tissue maybe difficult to interpret. In the current study, we isolated pyramidal c
Externí odkaz:
https://doaj.org/article/b8e169d732ac4e29afd84eac3f2589c9
Autor:
Jakob Norgren, Makrina Daniilidou, Ingemar Kåreholt, Shireen Sindi, Ulrika Akenine, Karin Nordin, Staffan Rosenborg, Tiia Ngandu, Miia Kivipelto, Anna Sandebring-Matton
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background: β-hydroxybutyrate (BHB) can upregulate brain-derived neurotrophic factor (BDNF) in mice, but little is known about the associations between BHB and BDNF in humans. The primary aim here was to investigate whether ketosis (i.e., raised BHB
Externí odkaz:
https://doaj.org/article/03760df5966c4c26a29808cdfd8abc34
Autor:
Natalie M. Hendrikse, Anna Sandegren, Tommy Andersson, Jenny Blomqvist, Åsa Makower, Dominik Possner, Chao Su, Niklas Thalén, Agneta Tjernberg, Ulrica Westermark, Johan Rockberg, Stefan Svensson Gelius, Per-Olof Syrén, Erik Nordling
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102154- (2021)
Summary: We show the successful application of ancestral sequence reconstruction to enhance the activity of iduronate-2-sulfatase (IDS), thereby increasing its therapeutic potential for the treatment of Hunter syndrome—a lysosomal storage disease c
Externí odkaz:
https://doaj.org/article/d39df5cce7224dbcaf4d0e1329c50468