Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anna Sancho Balsells"'
Autor:
Laura López-Molina, Anna Sancho-Balsells, Omar Al-Massadi, Enrica Montalban, Jordi Alberch, Belén Arranz, Jean-Antoine Girault, Albert Giralt
Publikováno v:
Neurobiology of Disease, Vol 194, Iss , Pp 106487- (2024)
Pyk2 has been shown previously to be involved in several psychological and cognitive alterations related to stress, Huntington's disease, and Alzheimer's disease. All these disorders are accompanied by different types of impairments in sociability, w
Externí odkaz:
https://doaj.org/article/247d3641159b40289b2f850753945ccc
RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer’s disease
Autor:
Leticia Pérez-Sisqués, Anna Sancho-Balsells, Júlia Solana-Balaguer, Genís Campoy-Campos, Marcel Vives-Isern, Ferran Soler-Palazón, Marta Anglada-Huguet, Miguel-Ángel López-Toledano, Eva-Maria Mandelkow, Jordi Alberch, Albert Giralt, Cristina Malagelada
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Abstract RTP801/REDD1 is a stress-regulated protein whose upregulation is necessary and sufficient to trigger neuronal death. Its downregulation in Parkinson’s and Huntington’s disease models ameliorates the pathological phenotypes. In the contex
Externí odkaz:
https://doaj.org/article/dd2fb29473404df5adcecc84c09efbe1
Autor:
Ened Rodríguez-Urgellés, Anna Sancho-Balsells, Wanqi Chen, Laura López-Molina, Ivan Ballasch, Ignacio del Castillo, Conxita Avila, Jordi Alberch, Albert Giralt
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Glycogen synthase kinase 3β (GSK3β) is a core protein, with a relevant role in many neurodegenerative disorders including Alzheimer’s disease. The enzyme has been largely studied as a potential therapeutic target for several neurological diseases
Externí odkaz:
https://doaj.org/article/d60990af8ded45d1b95ff150c2ee6b91
Autor:
Anna Sancho-Balsells, Esther García-García, Francesca Flotta, Wanqi Chen, Jordi Alberch, Manuel J. Rodríguez, Conxita Avila, Albert Giralt
Publikováno v:
Marine Drugs, Vol 20, Iss 10, p 648 (2022)
Major depression disorder (MDD) is a severe mental alteration with a multifactorial origin, and chronic stress is one of the most relevant environmental risk factors associated with MDD. Although there exist some therapeutical options, 30% of patient
Externí odkaz:
https://doaj.org/article/ce9bf713c5f24197a5b73dc435de4295
Autor:
Iván Ballasch, Esther García-García, Cristina Vila, Anna Pérez-González, Anna Sancho-Balsells, Jéssica Fernández, David Soto, Mar Puigdellívol, Xavier Gasull, Jordi Alberch, Manuel J. Rodríguez, Josep M. Canals, Albert Giralt
Publikováno v:
Brain, Behavior, and Immunity. 109:144-161
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b1b051410a930033c766c81bf1dc39a
https://doi.org/10.1016/j.bbi.2023.01.016
https://doi.org/10.1016/j.bbi.2023.01.016
Autor:
Anna Sancho-Balsells, Veronica Brito, Belissa Fernández, Mónica Pardo, Marco Straccia, Silvia Ginés, Jordi Alberch, Isabel Hernández, Belén Arranz, Josep M. Canals, Albert Giralt
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
The role of the WDFY1 protein has been studied as a TLR3/4 scaffold/recruiting protein in the immune system and in different oncogenic conditions. However, its function in brain remains poorly understood. We have found that in mice devoid of Helios (
Externí odkaz:
https://doaj.org/article/3e39a3e6560c4051a6efe7a72021df6c
Autor:
Leticia Pérez-Sisqués, Júlia Solana-Balaguer, Genís Campoy-Campos, Núria Martín-Flores, Anna Sancho-Balsells, Marcel Vives-Isern, Ferran Soler-Palazón, Marta Garcia-Forn, Mercè Masana, Jordi Alberch, Esther Pérez-Navarro, Albert Giralt, Cristina Malagelada
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 34 (2021)
RTP801/REDD1 is a stress-regulated protein whose levels are increased in several neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and Huntington’s diseases (HD). RTP801 downregulation ameliorates behavioral abnormalities in several
Externí odkaz:
https://doaj.org/article/f8ca9f36a15e407595f7559831020d37
Autor:
Verónica Brito, Enrica Montalban, Anna Sancho-Balsells, Anika Pupak, Francesca Flotta, Mercè Masana, Silvia Ginés, Jordi Alberch, Claire Martin, Jean-Antoine Girault, Albert Giralt
Publikováno v:
J Neurosci
Motor skills learning is classically associated with brain regions including cerebral and cerebellar cortices and basal ganglia nuclei. Less is known about the role of the hippocampus in the acquisition and storage of motor skills. Here, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc09926798fd960ebed98f97e37798fe
https://doi.org/10.1523/jneurosci.2258-21.2022
https://doi.org/10.1523/jneurosci.2258-21.2022
Autor:
Anika Pupak, Ankita Singh, Anna Sancho-Balsells, Rafael Alcalá-Vida, Marc Espina, Albert Giralt, Eulàlia Martí, Ulf Andersson Vang Ørom, Silvia Ginés, Verónica Brito
Publikováno v:
Pupak, A, Singh, A, Sancho-Balsells, A, Alcalá-Vida, R, Espina, M, Giralt, A, Martí, E, Ørom, U A V, Ginés, S & Brito, V 2022, ' Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington’s disease mice ', Cellular and Molecular Life Sciences, vol. 79, no. 8, 416 . https://doi.org/10.1007/s00018-022-04444-6
N6-methyladenosine (m6A) regulates many aspects of RNA metabolism and is involved in learning and memory processes. Yet, the impact of a dysregulation of post-transcriptional m6A editing on synaptic impairments in neurodegenerative disorders remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487f7e90ea2c9b3a88ce0ade9ba0ae94
https://doi.org/10.1007/s00018-022-04444-6
https://doi.org/10.1007/s00018-022-04444-6
Autor:
Yuriy Pomeshchik, Oxana Klementieva, Jeovanis Gil, Isak Martinsson, Marita Grønning Hansen, Tessa de Vries, Anna Sancho-Balsells, Kaspar Russ, Ekaterina Savchenko, Anna Collin, Ana Rita Vaz, Silvia Bagnoli, Benedetta Nacmias, Claire Rampon, Sandro Sorbi, Dora Brites, György Marko-Varga, Zaal Kokaia, Melinda Rezeli, Gunnar K. Gouras, Laurent Roybon
Publikováno v:
Stem Cell Reports
Stem Cell Reports, 2020, 15, pp.256-273. ⟨10.1016/j.stemcr.2020.06.001⟩
Stem Cell Reports, Elsevier, 2020, 15, pp.256-273. ⟨10.1016/j.stemcr.2020.06.001⟩
Stem Cell Reports, 2020, 15, pp.256-273. ⟨10.1016/j.stemcr.2020.06.001⟩
Stem Cell Reports, Elsevier, 2020, 15, pp.256-273. ⟨10.1016/j.stemcr.2020.06.001⟩
Summary The hippocampus is important for memory formation and is severely affected in the brain with Alzheimer disease (AD). Our understanding of early pathogenic processes occurring in hippocampi in AD is limited due to tissue unavailability. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae501c26d2639ec638a34e56e99e00a
http://europepmc.org/articles/PMC7363942
http://europepmc.org/articles/PMC7363942