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of 5
pro vyhledávání: '"Anna Sanchez Avila"'
Autor:
Wan-Ping Huang, Brittany C.S. Ellis, Rachel E. Hodgson, Anna Sanchez Avila, Vedanth Kumar, Jessica Rayment, Tobias Moll, Tatyana A. Shelkovnikova
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114421- (2024)
Summary: TDP-43 protein is dysregulated in several neurodegenerative diseases, which often have a multifactorial nature and may have extrinsic stressors as a “second hit.” TDP-43 undergoes reversible nuclear condensation in stressed cells includi
Externí odkaz:
https://doaj.org/article/04538c47df7d47c29b8b037208cea959
Autor:
Zsofia I. Laszlo, Nicole Hindley, Anna Sanchez Avila, Rachel A. Kline, Samantha L. Eaton, Douglas J. Lamont, Colin Smith, Tara L. Spires-Jones, Thomas M. Wishart, Christopher M. Henstridge
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Increasing evidence suggests synaptic dysfunction is a central and possibly triggering factor in Amyotrophic Lateral Sclerosis (ALS). Despite this, we still know very little about the molecular profile of an ALS synapse. To address this gap,
Externí odkaz:
https://doaj.org/article/a5dc3dda62ae45789b1d7df6f27a7cc3
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 15 (2023)
Synapses are integral for healthy brain function and are becoming increasingly recognized as key structures in the early stages of brain disease. Understanding the pathological processes driving synaptic dysfunction will unlock new therapeutic opport
Externí odkaz:
https://doaj.org/article/68bd33e6a499482eaced33db38d227e5
Autor:
Kokaia, Apostolos Mikroulis, Eliška Waloschková, Johan Bengzon, David Woldbye, Lars H. Pinborg, Bo Jespersen, Anna Sanchez Avila, Zsofia I. Laszlo, Christopher Henstridge, Marco Ledri, Merab
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13190
Glial cell line-derived neurotrophic factor (GDNF) has been shown to counteract seizures when overexpressed or delivered into the brain in various animal models of epileptogenesis or chronic epilepsy. The mechanisms underlying this effect have not be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::ac7c348d0ddb37196c9de1dfe72a2c8d
Publikováno v:
Neuronal Signaling. 6
Synapses are minuscule, intricate structures crucial for the correct communication between neurons. In the 125 years since the term synapse was first coined, we have advanced a long way when it comes to our understanding of how they work and what the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a2ebe492f42ededfe272e6767d64e1
https://doi.org/10.1042/ns20220013
https://doi.org/10.1042/ns20220013