The Evaluation of L-Tryptophan Derivatives as Inhibitors of the LType Amino Acid Transporter LAT1 (SLC7A5)

Autor: Julien Graff, Jennifer Müller, Anna Sadurní, Matthias Rubin, Inês André Canivete Cuissa, Claudia Keller, Marco Hartmann, Simon Singer, Jürg Gertsch, Karl‐Heinz Altmann

Publikováno v: ChemMedChem, 17 (17)

A series of derivatives of the substrate amino acid l-tryptophan have been investigated for inhibition of the L-type amino acid transporter LAT1 (SLC7A5), which is an emerging target in anticancer drug discovery. Of the four isomeric 4-, 5-, 6-, or 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f2e82096bf6b25c1435d8d9e9e6dc0

Designed asymmetric coordination helicates with bis-beta-diketonate ligands

Autor: David Aguilà, Rosa Diego, Leoní A. Barrios, Paul Lloyd-Williams, Olivier Roubeau, Mohanad Darawsheh, Simon J. Teat, Anna Sadurní, Guillem Aromí, Jordi Garcia

Publikováno v: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Digital.CSIC. Repositorio Institucional del CSIC
Dalton transactions (Cambridge, England : 2003), vol 48, iss 45
Dipòsit Digital de la UB
Universidad de Barcelona
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza

A new bis-(β-diketone) ligand featuring built-up structural asymmetry yields non-symmetric Fe(III) and Ga(III) dinuclear, triple-stranded helicates by design. Their structural properties have been studied, both in solid state and in solution, and co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410836e6a7fa9e2f2e3f230b81872725
http://zaguan.unizar.es/record/95905

Molecules Designed to Contain Two Weakly Coupled Spins with a Photo-switchable Spacer

Autor: Olivier Roubeau, Marta Estrader, Jorge Salinas Uber, Joris van Slageren, Nicholas F. Chilton, Simon J. Teat, Jordi Garcia, Jordi Ribas-Arino, Guillem Aromí, Anna Sadurní, Dominik Dengler, Paul Lloyd-Williams

Publikováno v: Aromi, G, Salinas Uber, J, Estrader, M, Garcia, J, Lloyd-Williams, P, Sadurní, A, Dengler, D, van Slageren, J, Chilton, N, Roubeau, O, Teat, S J & Ribas-Ariño, J 2017, ' Molecules Designed to Contain Two Weakly Coupled Spins with a Photo-switchable Spacer ', Chemistry: A European Journal . https://doi.org/10.1002/chem.201702171
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Digital.CSIC. Repositorio Institucional del CSIC

Controlling the charges and spins of molecules lies at the heart of spintronics. A photoswitchable molecule consisting of two independent spins separated by a photoswitchable moiety was designed in the form of new ligand H4L, which features a dithien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45743dabb681a615c9d665cd8e79e5fe
https://doi.org/10.1002/chem.201702171

Cover Feature: Fluorine-Directed Glycosylation Enables the Stereocontrolled Synthesis of Selective SGLT2 Inhibitors for Type II Diabetes (Chem. Eur. J. 12/2018)

Autor: Gerald Kehr, Marie Ahlqvist, Helena Peilot Sjögren, Anna Sadurní, Johan Wernevik, Ryan Gilmour, Laurent Knerr, Cecilia Kankkonen

Publikováno v: Chemistry - A European Journal. 24:2791-2791

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f82456e163d28b5c9d690b284e840fa3
https://doi.org/10.1002/chem.201800108

Nucleic acid i-motif structures in analytical chemistry

Autor: Joan Josep Alba, Anna Sadurní, Raimundo Gargallo

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Under the appropriate experimental conditions of pH and temperature, cytosine-rich segments in DNA or RNA sequences may produce a characteristic folded structure known as an i-motif. Besides its potential role in vivo, which is still under investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939fef05fdef0599045e582d56b244db
http://hdl.handle.net/2445/127829