Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Anna Sadakierska- Chudy"'
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Akademický článek
MicroRNAs: Diverse Mechanisms of Action and Their Potential Applications as Cancer Epi-Therapeutics
Autor: Anna Sadakierska-Chudy
Publikováno v: Biomolecules, Vol 10, Iss 9, p 1285 (2020)
Usually, miRNAs function post-transcriptionally, by base-pairing with the 3′UTR of target mRNAs, repressing protein synthesis in the cytoplasm. Furthermore, other regions including gene promoters, as well as coding and 5′UTR regions of mRNAs are
Externí odkaz: https://doaj.org/article/25fc86eb47b44cb686eb5173a8df9e1a
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Antipsychotic drug-aripiprazole against schizophrenia, its therapeutic and metabolic effects associated with gene polymorphisms
Autor: Adriana Stelmach, Katarzyna Guzek, Alicja Rożnowska, Irena Najbar, Anna Sadakierska-Chudy
Publikováno v: Pharmacological reports : PR.
Second-generation antipsychotics are widely used for the treatment of schizophrenia. Aripiprazole (ARI) is classified as a third-generation antipsychotic drug with a high affinity for dopamine and serotonin receptors. It is considered a dopamine-syst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c95560d64991f4ca71a00724047a51
https://pubmed.ncbi.nlm.nih.gov/36526889
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4
Assessment of metabolic and hormonal profiles and striatal dopamine D2 receptor expression following continuous or scheduled high-fat or high-sucrose diet in rats
Autor: Beata Bystrowska, Bartłomiej Rospond, Anna Sadakierska-Chudy, Grzegorz Kazek, Mirosław Krośniak, Małgorzata Filip
Publikováno v: Pharmacological Reports. 71:1-12
Background Obesity has reached global epidemic proportions and is associated with serious medical comorbidities and economic consequences. In this preclinical study, we characterized how the palatable diet changed food intake pattern, caloric intake,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89cacef3ca4f2def1e295223486fef69
https://doi.org/10.1016/j.pharep.2018.09.005
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7
Disruption of Glutamate Homeostasis in the Brain of Rat Offspring Induced by Prenatal and Early Postnatal Exposure to Maternal High-Sugar Diet
Autor: Jozef Mizera, Bartosz Pomierny, Anna Sadakierska-Chudy, Beata Bystrowska, Lucyna Pomierny-Chamiolo
Publikováno v: Nutrients; Volume 14; Issue 11; Pages: 2184
A high-calorie diet has contributed greatly to the prevalence of overweight and obesity worldwide for decades. These conditions also affect pregnant women and have a negative impact on the health of both the woman and the fetus. Numerous studies indi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd15de9159a297745480780fe6f2733
https://doi.org/10.3390/nu14112184
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Downregulation of gene expression and the outcome of ICSI in severe oligozoospermic patients: A preliminary study
Autor: J Patrylak, Anna Sadakierska-Chudy, J Chudy, J Janeczko
Publikováno v: Molecular reproduction and developmentREFERENCES. 87(12)
Preimplantation embryo development might be influenced by a specific set of transcripts that are delivered to the oocyte by the sperm. The aim of the study was to determine the relationship between the level of selected transcripts in spermatozoa and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f48578eda1810366d0b1038be5ac3c
https://pubmed.ncbi.nlm.nih.gov/33241638
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Extinction Training after Cocaine Self-Administration Influences the Epigenetic and Genetic Machinery Responsible for Glutamatergic Transporter Gene Expression in Male Rat Brain
Autor: Agata Suder, Irena Smaga, Anna Sadakierska-Chudy, Marcin Piechota, Kinga Gawlińska, Małgorzata Frankowska, Małgorzata Filip, Karolina Wydra
Publikováno v: Neuroscience. 451
Glutamate is a key excitatory neurotransmitter in the central nervous system. The balance of glutamatergic transporter proteins allows long-term maintenance of glutamate homeostasis in the brain, which is impaired during cocaine use disorder. The aim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981018e3b5e1801d0560852d3f2dd21a
https://pubmed.ncbi.nlm.nih.gov/33065231
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Identification and In Silico Characterization of a Novel COLGALT2 Gene Variant in a Child with Mucosal Rectal Prolapse
Autor: Anna Sadakierska-Chudy, Paweł Szymanowski, Arleta Lebioda, Rafał Płoski
Publikováno v: International Journal of Molecular Sciences. 23:3670
Rectal prolapse is influenced by many factors including connective tissue dysfunction. Currently, there is no data about genetic contribution in the etiology of this disorder. In this study, we performed trio whole-exome sequencing in an 11-year-old
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e03d373cffd7974cddea09207c170cd0
https://doi.org/10.3390/ijms23073670
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