Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anna S Gardberg"'
Autor:
Loren Baugh, Larry A Gallagher, Rapatbhorn Patrapuvich, Matthew C Clifton, Anna S Gardberg, Thomas E Edwards, Brianna Armour, Darren W Begley, Shellie H Dieterich, David M Dranow, Jan Abendroth, James W Fairman, David Fox, Bart L Staker, Isabelle Phan, Angela Gillespie, Ryan Choi, Steve Nakazawa-Hewitt, Mary Trang Nguyen, Alberto Napuli, Lynn Barrett, Garry W Buchko, Robin Stacy, Peter J Myler, Lance J Stewart, Colin Manoil, Wesley C Van Voorhis
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53851 (2013)
BACKGROUND:The genus Burkholderia includes pathogenic gram-negative bacteria that cause melioidosis, glanders, and pulmonary infections of patients with cancer and cystic fibrosis. Drug resistance has made development of new antimicrobials critical.
Externí odkaz:
https://doaj.org/article/318d4103a02443b8b18e41dab9bdf5d6
Autor:
Anna S. Gardberg, Francois Brucelle, Robert J. Sims, Nico Cantone, Richard T. Cummings, Florence Poy, Archana Bommi-Reddy, Julian Levell, Jonathan E. Wilson, Chirag Patel, Annissa J. Huhn, Gaurav Patel
Publikováno v:
ACS Med Chem Lett
[Image: see text] The histone acetyltransferases, CREB binding protein (CBP) and EP300, are master transcriptional co-regulators that have been implicated in numerous diseases, such as cancer, inflammatory disorders, and neurodegeneration. A novel, h
Autor:
Valerie Vivat, Florence Poy, Annissa J. Huhn, Jeremy W. Setser, Jonathan E. Wilson, Francois Brucelle, Richard D. Cummings, Anna S. Gardberg, Archana Bommi-Reddy
Publikováno v:
Structural Dynamics, Vol 6, Iss 5, Pp 054702-054702-5 (2019)
Structural Dynamics
Structural Dynamics
Histone acetyltransferases (HATs) and histone deacetylases (HDACs) catalyze the dynamic and reversible acetylation of proteins, an epigenetic regulatory mechanism associated with multiple cancers. Indeed, HDAC inhibitors are already approved in the c
Autor:
Lezlee T. Dice, Ronald Wetzel, Anna S. Gardberg, Kathleen Pridgen, Susan Ou, Paul H. Patterson, Jan Ko, Chris Dealwis
Publikováno v:
Biochemistry. 48:5210-5217
Passive immunotherapy (PI) is being explored as a potential therapeutic against Alzheimer's disease. The most promising antibodies (Abs) used in PI target the EFRH motif of the Abeta N-terminus. The monoclonal anti-Abeta Ab PFA1 recognizes the EFRH e
Publikováno v:
Inorganic Chemistry. 41:1778-1781
The first integrally oxidized metal-free phthalocyanine compounds have been synthesized by chemical oxidation. Phthalocyanine (H2(pc), pc = phthalocyaninato) was oxidized with IBr to afford the compounds [H2(pc)][IBr2] (1) and [H2(pc)]2[IBr2]BrAC10H7
Publikováno v:
Inorganic Chemistry. 35:6358-6361
Vibrant blue crystals of Na(4)Mn(0.5)P(0.5)O(5) were synthesized via a sodium hydroxide flux. The X-ray structural analysis showed that this sodium manganese(VII) phosphorous oxide crystallizes in an orthorhombic lattice with a = 8.967(3) Å, b = 7.2
Publikováno v:
Angewandte Chemie International Edition. 40:244-246
Publikováno v:
ChemInform. 28
Vibrant blue crystals of Na4Mn0.5P0.5O5 were synthesized via a sodium hydroxide flux. The X-ray structural analysis showed that this sodium manganese(VII) phosphorous oxide crystallizes in an orthorhombic lattice with a = 8.967(3) A, b = 7.291(3) A,
Publikováno v:
ChemInform. 33
The first cubane-like polysulfidomolybdate, Cs6[Mo4S23.6], has been synthesized by the reaction of Mo6Br12 with Cs2S3 in water. The structure comprises a [Mo4S4]6+ tetrahedral core with a combinati...
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. (Pt 7)
The hydrogen/deuterium-exchange (HDX) method, coupled with neutron diffraction, is a powerful probe for investigating molecular dynamics. In the present report, general determinants of HDX are proposed based on 12 deposited neutron protein structures