Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anna S, Pavlova"'
Autor:
Anna S. Pavlova, Daniil A. Buslaev, Nataliya E. Borisova, Victor V. Temnov, Alexey A. Nazarov, Tatyana A. Podrugina
Publikováno v:
Molbank, Vol 2023, Iss 1, p M1564 (2023)
A huge variety of types of cancer makes it necessary to search for new effective drugs with a defined molecular target. Modification of substituents in ligands based on 3-hydroxy-1,1-cyclobutanedicarboxylic acid are one of the effective directions to
Externí odkaz:
https://doaj.org/article/346b1b4154bf480887bab1f4dd36c676
Autor:
Maria B. Sokol, Margarita V. Chirkina, Nikita G. Yabbarov, Mariia R. Mollaeva, Tatyana A. Podrugina, Anna S. Pavlova, Viktor V. Temnov, Rania M. Hathout, Abdelkader A. Metwally, Elena D. Nikolskaya
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2333 (2022)
Currently, molecular dynamics simulation is being widely applied to predict drug–polymer interaction, and to optimize drug delivery systems. Our study describes a combination of in silico and in vitro approaches aimed at improvement in polymer-base
Externí odkaz:
https://doaj.org/article/bf9a0587d234408699b4ff6024953dd5
Autor:
Anna S. Pavlova, Ilya S. Dovydenko, Maxim S. Kupryushkin, Alina E. Grigor’eva, Inna A. Pyshnaya, Dmitrii V. Pyshnyi
Publikováno v:
Nanomaterials, Vol 10, Iss 10, p 1948 (2020)
The conjugation of lipophilic groups to oligonucleotides is a promising approach for improving nucleic acid-based therapeutics’ intracellular delivery. Lipid oligonucleotide conjugates can self-aggregate in aqueous solution, which gains much attent
Externí odkaz:
https://doaj.org/article/4f7b094ad24a479ab6c55f383830384d
Problems of the Synthesis of Oligonucleotide Derivatives in the Realization of the Anchimeric Effect
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:505-513
It has been found that the presence of a free OH group at the 3'-terminal residue of the substituted ethylene glycol fragment in a phosphoryl guanidine oligodeoxyribonucleotide derivative is a factor that determines the instability of the structure o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95a097fa71f2cfae2c120fcfc7777f57
https://doi.org/10.1134/s1068162021020096
https://doi.org/10.1134/s1068162021020096
Autor:
Elena I. Ryabchikova, Anna S. Pavlova, Kristina I. Yakovleva, Inna A. Pyshnaya, Anna V. Epanchitseva, Dmitrii V. Pyshnyi, Ilya S. Dovydenko, Maxim S. Kupryushkin
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9784, p 9784 (2021)
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9784, p 9784 (2021)
Volume 22
Issue 18
Small interfering RNA (siRNA) is the most important tool for the manipulation of mRNA expression and needs protection from intracellular nucleases when delivered into the cell. In this work, we examined the effects of siRNA modification with the phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d2b88992daccaa9a5bf68879a442d3
http://europepmc.org/articles/PMC8467447
http://europepmc.org/articles/PMC8467447
Autor:
L. S. Koroleva, Anna S. Pavlova, D. V. Pyshnyi, Vladimir N. Silnikov, Inna Yu. Serpokrylova, Alexander A. Lomzov, P. A. Ogurtsova, Inna A. Pyshnaya
Publikováno v:
Russian Journal of Bioorganic Chemistry. 45:813-824
Novel bisimidazole-containing peptidomimetic molecules, which can efficiently cleave RNA in the absence of divalent metal ions have been synthesized. The thymidine 5'-monophosphate derivatives modified with these peptidomimetics have been obtained on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d84f00a1b511d3b9d5cdd28d9f5bb65a
https://doi.org/10.1134/s1068162019060311
https://doi.org/10.1134/s1068162019060311
Autor:
M. G. Zadneprianetc, Tatiana S. Hramco, E. A. Kulikova, E. V. Smirnova, Anna S. Pavlova, Anfisa S. Filatova, Daria D. Shamina, Marina E. Krupnova, Alla Boreyko
Publikováno v:
PROCEEDINGS OF THE 24TH INTERNATIONAL SCIENTIFIC CONFERENCE OF YOUNG SCIENTISTS AND SPECIALISTS (AYSS-2020).
High-order clustered DNA lesions are the hallmark of the action of dense-ionizing radiation. It is defined as a combination of two or more individual lesions (single-strand breaks (SSB) and double-strand breaks (DSB), base damage, etc.) located withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efa9f82b9a5a1caa11d4ca7a66cfa67d
https://doi.org/10.1063/5.0063357
https://doi.org/10.1063/5.0063357
Autor:
Georgii D Ozhegov, Airat R. Kayumov, D. Zhuravleva, Elena Shagimardanova, D. R. Yarullina, Maria I. Markelova, Anna S Pavlova, Natalia E. Gogoleva
Publikováno v:
Data in Brief, Vol 32, Iss, Pp 106105-(2020)
Here we report the whole genome sequence of Lactobacillus fermentum HFD1 strain, the producer of antibacterial peptides. The genome consists of one circular chromosome with 2101878 bp in length and GC-content of 51.8%, and includes linear DNA with 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf78c3ee607e63ec663de300c8d1d5f1
http://www.sciencedirect.com/science/article/pii/S2352340920309999
http://www.sciencedirect.com/science/article/pii/S2352340920309999
Autor:
Anna S. Pavlova, Zinfer R. Ismagilov, Asya S. Levina, Valentina F. Zarytova, N. A. Mazurkova, Nadezhda V. Shikina, Maxim S. Kupryushkin, Marina Repkova, Dmitrii V. Pyshnyi
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 162
This study describes the effective attack of oligonucleotides on the viral genome of highly pathogenic H5N1 influenza A virus (IAV) in vivo using for the first time the new delivery system consisting of biocompatible low-toxic titanium dioxide nanopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c6d75a6de7f8e1723be86b113d2ea5
https://pubmed.ncbi.nlm.nih.gov/33753212
https://pubmed.ncbi.nlm.nih.gov/33753212
Autor:
Georgii D Ozhegov, Nikolai A Alemasov, Vadim M. Govorun, E. S. Fomin, Airat R. Kayumov, Vadim T. Ivanov, Anna S Pavlova, Ivan Butenko, Dmitry A. Afonnikov, D. R. Yarullina, Georgij Arapidi
Publikováno v:
The protein journal. 39(1)
Antimicrobial peptides (AMPs) are natural antagonistic tools of many bacteria and are considered as attractive antimicrobial agents for the treatment of bacteria with multidrug resistance. Lactic acid bacteria from the gastrointestinal tract of anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5ac792ab2b8d58984cfc9f5fbf374a
https://pubmed.ncbi.nlm.nih.gov/31933011
https://pubmed.ncbi.nlm.nih.gov/31933011