Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anna Ruckdeschel"'
Autor:
Cornelia Schuster, Badr Kiaf, Teri Hatzihristidis, Anna Ruckdeschel, Janice Nieves-Bonilla, Yuki Ishikawa, Bin Zhao, Peilin Zheng, Paul E. Love, Stephan Kissler
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
CD5 is constitutively expressed on all T cells and is a negative regulator of lymphocyte function. However, the full extent of CD5 function in immunity remains unclear. CD5 deficiency impacts thymic selection and extra-thymic regulatory T cell genera
Externí odkaz:
https://doaj.org/article/a8a4974b10fa4294a86c90e79d3bac37
Autor:
Alexander M. Leipold, Rudolf A. Werner, Johannes Düll, Pius Jung, Mara John, Emilia Stanojkovska, Xiang Zhou, Hannah Hornburger, Anna Ruckdeschel, Oliver Dietrich, Fabian Imdahl, Tobias Krammer, Stefan Knop, Andreas Rosenwald, Andreas Buck, Leif Erik Sander, Hermann Einsele, K. Martin Kortüm, Antoine-Emmanuel Saliba, Leo Rasche
Publikováno v:
Leukemia. 37:650-658
Pseudo-progression and flare-up phenomena constitute a novel diagnostic challenge in the follow-up of patients treated with immune-oncology drugs. We present a case study on pulmonary flare-up after Idecabtagen Vicleucel (Ide-cel), a BCMA targeting C
Autor:
Thorsten Stühmer, Cornelia Vogt, Manik Chatterjee, Rafael Alonso Fernández, José I. Martín-Subero, K. Martin Kortüm, Peter Raab, Seungbin Han, Larissa Haertle, Yanira Ruiz-Heredia, Umair Munawar, Jan Krönke, Miriam Kull, Leo Rasche, Xiang Zhou, Hermann Einsele, Xabier Agirre, Niccolo Bolli, Anna Ruckdeschel, Josip Zovko, Joaquin Martinez-Lopez, Andoni Garitano-Trojaola, Matteo Claudio Da Via, Max Bittrich, Thomas Haaf, Santiago Barrio
Publikováno v:
Blood
Cereblon is the direct binding target of the immunomodulatory drugs (IMiDs) that are commonly used to treat multiple myeloma (MM), the second most frequent hematologic malignancy. Patients respond well to initial treatment with IMiDs, but virtually a
Autor:
Larissa Haertle, Wencke Walter, Matteo Claudio Da Via, Angela Riedel, Mara John, K. Martin Kortüm, Xiang Zhou, Andreas Rosenwald, Sebastian Hüper, Niels Weinhold, Manja Meggendorfer, Anna Ruckdeschel, Max S. Topp, Johannes Duell, Jessica Peter, Niccolo Bolli, Claudia Haferlach, Hermann Einsele, Larissa Heimeshoff, Marietta Truger, Leo Rasche
Publikováno v:
Blood Adv
T cell–engaging immunotherapies exert unprecedented single-agent activity in multiple myeloma (MM), thereby putting a yet unexplored selective pressure on the clonal architecture. In this study, we report on homozygous BCMA (TNFRSF17) gene deletion
Autor:
Alexander Leipold, Rudolf Werner, Johannes Duell, Pius Jung, Mara John, Emilia Stanojkovska, Xiang Zhou, Anna Ruckdeschel, Oliver Dietrich, Fabian Imdahl, Tobias Krammer, Andreas Buck, Julia Mersi, Hermann Einsele, K. Martin Kortuem, Antoine-Emmanuel Saliba, Leo Rasche
Publikováno v:
Blood. 140:10020-10021
Autor:
Hannah Hornburger, Maximilian Johannes Steinhardt, Jessica Peter, Leo Rasche, S. Danhof, Xiang Zhou, Larissa Heimeshoff, Klaus Martin Kortüm, Anna Ruckdeschel, Hermann Einsele, David Böckle
Publikováno v:
Hematological oncologyREFERENCES. 40(2)
The multi-agent therapy “VDT-PACE” represents an established regimen in relapsed/refractory multiple myeloma (RRMM). Here, we report on our experience with a “modified VDT-PACE” incorporating new generation anti-MM agents daratumumab and carf
Autor:
Thorsten Stühmer, Martina Rudelius, Vanessa Desantis, Angelo Vacca, Zeinab Mokhtari, Anna Ruckdeschel, Paolo Trerotoli, Max Bittrich, Miriam Ritz, Andreas Rosenwald, Franz Jakob, H. Einsele, Regina Ebert, Antonio Giovanni Solimando, Julia Dotterweich, Andreas Beilhack, Carolin Graf, Andreas Brandl, Katharina Mattenheimer, Ma Frassanito
Publikováno v:
Leukemia
Cell adhesion in the multiple myeloma (MM) microenvironment has been recognized as a major mechanism of MM cell survival and the development of drug resistance. Here we addressed the hypothesis that the protein junctional adhesion molecule-A (JAM-A)
Autor:
Cornelia Schuster, Mi-Jeong Kim, Kay D. Gerold, Lilli Probst, Anna Ruckdeschel, Thomas Serwold, Stephan Kissler, Kevin Boerner, Kilian Schober
Publikováno v:
Immunity. 42(5):942-952
SummaryCLEC16A variation has been associated with multiple immune-mediated diseases, including type 1 diabetes, multiple sclerosis, systemic lupus erythematosus, celiac disease, Crohn’s disease, Addison’s disease, primary biliary cirrhosis, rheum
Autor:
Antonio Giovanni Solimando, Rodolfo Sbrojavacca, Hermann Einsele, Anna Ruckdeschel, Georg Fritz, Angelo Vacca, Maxbittrich, Antonella Argentiero, Andreas Schneider
Publikováno v:
International Journal of Critical Care and Emergency Medicine. 3
Autor:
Claudia Covelli, Peter Kraus, Angelo Vacca, Hermann Einsele, Anna Ruckdeschel, Antonella Argentiero, Antonio Giovanni Solimando
Publikováno v:
Journal of Cell Science & Therapy.
Mucormycosis are an emerging group of life-threatening fungal infections caused by filamentous fungi of the Mucorales family. Mucormycosis are most common in stem-cell transplant recipients and patients with underlying hematologic malignancies, poorl