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pro vyhledávání: '"Anna Roshani Dashtmian"'
Autor:
Greta Bernardo, Miguel A. Prado, Anna Roshani Dashtmian, Mariavittoria Favaro, Sofia Mauri, Alice Borsetto, Elena Marchesan, Joao A. Paulo, Steve P. Gygi, Daniel J. Finley, Elena Ziviani
Publikováno v:
Pharmacological Research, Vol 210, Iss , Pp 107484- (2024)
Loss of proteostasis is well documented during physiological aging and depends on the progressive decline in the activity of two major degradative mechanisms: the ubiquitin-proteasome system (UPS) and the autophagy-lysosomal pathway. This decline in
Externí odkaz:
https://doaj.org/article/0e236267259b4ce9b24ea8286377cdf1
Publikováno v:
Cells, Vol 13, Iss 11, p 928 (2024)
Amyotrophic Lateral Sclerosis (ALS) is a group of sporadic and genetic neurodegenerative disorders that result in losses of upper and lower motor neurons. Treatment of ALS is limited, and survival is 2–5 years after disease onset. While ALS can occ
Externí odkaz:
https://doaj.org/article/12230e6c1c5745988266cb3c0720dc6b