Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Anna Ritz"'
Autor:
Andy Zhao, Sophia Varady, Madelyn O’Kelley-Bangsberg, Vicki Deng, Amy Platenkamp, Petra Wijngaard, Miriam Bern, Wyatt Gormley, Elaine Kushkowski, Kat Thompson, Logan Tibbetts, A. Tamar Conner, David Noeckel, Aidan Teran, Anna Ritz, Derek A. Applewhite
Publikováno v:
BMC Molecular and Cell Biology, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract The morphogenetic process of apical constriction, which relies on non-muscle myosin II (NMII) generated constriction of apical domains of epithelial cells, is key to the development of complex cellular patterns. Apical constriction occurs in
Externí odkaz:
https://doaj.org/article/884755eac3374ae78e65eac78dc3146a
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S16, Pp 1-15 (2019)
Abstract Background Understanding cellular responses via signal transduction is a core focus in systems biology. Tools to automatically reconstruct signaling pathways from protein-protein interactions (PPIs) can help biologists generate testable hypo
Externí odkaz:
https://doaj.org/article/36c66fcf4e6945abb6666f3e7e85b2e0
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1009133 (2021)
Externí odkaz:
https://doaj.org/article/fcc477b4c8a54928a845b308325d70b0
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S12, Pp 1-13 (2019)
Abstract Background Schizophrenia and autism are examples of polygenic diseases caused by a multitude of genetic variants, many of which are still poorly understood. Recently, both diseases have been associated with disrupted neuron motility and migr
Externí odkaz:
https://doaj.org/article/96741b6a7b144d0ea10bfca65ce4a131
Autor:
Hui-wen Lue, Daniel S. Derrick, Soumya Rao, Ahna Van Gaest, Larry Cheng, Jennifer Podolak, Samantha Lawson, Changhui Xue, Devin Garg, Ralph White, III, Christopher W. Ryan, Justin M. Drake, Anna Ritz, Laura M. Heiser, George V. Thomas
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100267- (2021)
Summary: The lack of effective treatment options for advanced non-clear cell renal cell carcinoma (NCCRCC) is a critical unmet clinical need. Applying a high-throughput drug screen to multiple human kidney cancer cells, we identify the combination of
Externí odkaz:
https://doaj.org/article/81d895defe654fc78a2802b6f737cb09
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 10, p e1007384 (2019)
Characterizing cellular responses to different extrinsic signals is an active area of research, and curated pathway databases describe these complex signaling reactions. Here, we revisit a fundamental question in signaling pathway analysis: are two m
Externí odkaz:
https://doaj.org/article/27f8ef39ed154391a5349dd00b36a7a4
Autor:
Lulu Cao, Yiyuan Ding, Norris Hung, Kebing Yu, Anna Ritz, Benjamin J Raphael, Arthur R Salomon
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46725 (2012)
The SH2-domain-containing leukocyte protein of 76 kDa (SLP-76) plays a critical scaffolding role in T cell receptor (TCR) signaling. As an adaptor protein that contains multiple protein-binding domains, SLP-76 interacts with many signaling molecules
Externí odkaz:
https://doaj.org/article/819cafe9b36541a29c5e3274c42fb840
Autor:
Hannah S. Meier, Isaac J. Schuman, Tamara J. Layden, Anna Ritz, Colin T. Kremer, Samuel B. Fey
Publikováno v:
Functional Ecology. 36:2969-2982
Publikováno v:
Journal of Computational Biology.
MotivationHigher-order interaction patterns among proteins have the potential to reveal mechanisms behind molecular processes and diseases. While clustering methods are used to identify functional groups within molecular interaction networks, these m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4d67eb22f2591f361343af430c19caf
https://doi.org/10.1101/2022.12.24.521876
https://doi.org/10.1101/2022.12.24.521876