Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Anna Rita Renzetti"'
Autor:
Sandro Giuliani, Marco Criscuoli, Enzo Perrotta, Carlo Alberto Maggi, Rossano Nannicini, Anna-Rita Renzetti, Nicholas J. S. Harmat, Riccardo Patacchini, Maria Altamura, Danilo Giannotti
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:693-696
A series of cyclic pseudopeptides were synthesized containing the sequence -Trp-Phe-( d )-PheΨCH 2 NH-, the terminal ends of which were bound to 2-carboxy succinate or enantiomerically enriched tricarballylic acid to give the final cyclic structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b9dfa9964747884d155ec03692e459
https://doi.org/10.1016/s0960-894x(01)00841-1
https://doi.org/10.1016/s0960-894x(01)00841-1
Autor:
Luigi Rotondaro, Paola Cucchi, Sabrina Zappitelli, Carlo Alberto Maggi, Anna Rita Renzetti, Alessandro Giolitti
Publikováno v:
Neuropharmacology. 39:1422-1429
A series of 14 mutants on nine selected residues of the human tachykinin NK 2 receptor was produced and stably transfected into CHO cells to investigate the binding of the peptide MEN 11420 and the nonpeptide SR 48968 antagonists. The main interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbaea60c42dc9866ca4d019bf679ed7
https://doi.org/10.1016/s0028-3908(00)00008-3
https://doi.org/10.1016/s0028-3908(00)00008-3
Autor:
Anna Rita Renzetti, Silvia Valenza, Franca M. Cordero, Alessandro Giolitti, Maria Altamura, Alberto Brandi, Francesca Giuntini, Antonio Guidi, Franco Pasqui, Carlo Alberto Maggi
Publikováno v:
The Journal of Organic Chemistry. 65:4003-4008
The regioselectivity and the stereoselectivity induced by relatively small peptidomimetic maleic diamide 1 in cycloaddition reactions with cyclic nitrones 2-5 was studied. The high regio- and stereoselectivity observed, sensibly increased by nonpolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6dac772fc88971b29f5a1b5dbe5261f
https://doi.org/10.1021/jo0000022
https://doi.org/10.1021/jo0000022
Autor:
Raffaello Giorgi, Stefania Santeusanio, Orazio A. Attanasi, Francesca R. Perrulli, Ada Perrone, Susanna Monti, Anna Rita Renzetti, Lucia De Crescentini, Spartaco Mauro Colombani
Publikováno v:
Il Farmaco. 54:64-76
Based on preliminary molecular modelling study, the synthesis of two different classes of biphenylyltetrazole derivatives of 1-aminopyrroles, as potentially active non-peptide angiotensin II (AII) antagonists, is reported. Some NH -Boc protected 1-am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90e91f1b4ed531ce03fb4a6fbc1104d
https://doi.org/10.1016/s0014-827x(98)00100-1
https://doi.org/10.1016/s0014-827x(98)00100-1
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 358:395-403
The human tachykinin NK2 receptor stably expressed in Chinese hamster ovary cells (CHO-hNK2R cells) was characterized by studying the effect of neurokinin A (NKA), the preferred natural ligand, and that of other agonists and antagonists in both bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd833b29f95fd9dcf7a4a2e5232defe1
https://doi.org/10.1007/pl00005270
https://doi.org/10.1007/pl00005270
Autor:
Anna-Rita Renzetti, A. Lippi, Marco Guelfi, Paola Cucchi, Marco Criscuoli, Carlo Alberto Maggi, R.-M. Catalioto, Laura Quartara
Publikováno v:
Biochemical and Biophysical Research Communications. 248:78-82
[ 3 H]MEN 11420, a radiolabeled glycosylated peptide antagonist of the tachykinin NK 2 receptor, has been investigated in ligand-receptor binding assays using membranes of CHO cells transfected with the human tachykinin NK 2 receptor. [ 3 H]MEN 11420
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ffa1e70f2ee17b6fa4b9f67e72c7d2
https://doi.org/10.1006/bbrc.1998.8883
https://doi.org/10.1006/bbrc.1998.8883
Autor:
A. Lippi, Marco Criscuoli, Paola Cucchi, Alessandro Lecci, Laura Quartara, C.A. Maggi, Antonio Giachetti, Federico Arcamone, Manuela Tramontana, R.-M. Catalioto, Sandro Giuliani, Riccardo Patacchini, Anna Rita Renzetti, D. Giannotti
Publikováno v:
British Journal of Pharmacology. 123:81-91
1. The pharmacological profile was studied of MEN 11420, or cyclo[[Asn(beta-D-GlcNAc)-Asp-Trp-Phe-Dap-Leu]cyclo(2beta-5beta )], a glycosylated derivative of the potent, selective, conformationally-constrained tachykinin NK2 receptor antagonist MEN 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ae5ffc76f183511156e051e56572e58
https://doi.org/10.1038/sj.bjp.0701587
https://doi.org/10.1038/sj.bjp.0701587
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 356:139-144
The tachykinin NK2 receptors present in membranes of rat small intestine were characterized by means of tachykinin receptor agonists and antagonists, by using the natural agonist, NKA, or the nonpeptide antagonist SR 48968, as radioligands. The affin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be30a072f609adb972de642882725826
https://doi.org/10.1007/pl00005021
https://doi.org/10.1007/pl00005021
Autor:
Anna Rita Renzetti, Fabrizio Bonaccorsi, Spartaco Mauro Colombani, C. Ghio, R. Giorgi, Nicholas J. S. Harmat, G. Alagona, Rocco Cirillo, Guido Cerbai, Alessandro Subissi
Publikováno v:
Journal of Medicinal Chemistry. 38:2925-2937
A series of N-[biphenylyl(tetrazolyl)methyl]-2-butylimidazoles containing variously substituted diazine or pyridine moieties either as their free bases or N-oxide derivatives attached to the 4-position of the imidazole ring was synthesized and tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bef8ecdcce3f7d82cbfbe10ab43eeec
https://doi.org/10.1021/jm00015a015
https://doi.org/10.1021/jm00015a015
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 290:151-156
This report describes the molecular pharmacological properties of LR-B/081 (methyl 2-[[4-butyl-2-methyl-6-oxo-5-[ [2′-(1H-tetrazol-5-yl) [1,1′-biphenyl]-4-yl]methyl]-1 (6H)-pyrimidinyl]methyl]-3-thiophenecarboxilate), a novel non-peptide angioten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a376b3422dabacdb3c0ebf7f5f9a4f0c
https://doi.org/10.1016/0922-4106(95)90028-4
https://doi.org/10.1016/0922-4106(95)90028-4